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A NEW APPROACH OF GLUTEN DERIVATIVES FOR ACTIVITY AS THEORETICAL

Yıl 2017, Cilt: 35 Sayı: 4, 757 - 760, 01.12.2017

Öz

Gluten is the mainly rubbery mass that remains after wheat dough is being washed to remove starch granules and water-soluble constituents. Gluten is known as proteins and it plays an important role in indicating the unique baking quality of wheat. Their derivatives can be divided into two main fractions;: one of them is the soluble gliadins and the other is insoluble glutenins. After intaken gluten and monosodyum glutamate, the salt form of glutamate, the quantity of glutamate and glutamic acid in blood increases. In our study; we investigate the chemical properties of gluten ,glutamic acid and monosodyum glutamate as theoretical by using RHF/STO-3G method for quantum chemical calculations and geometry optimization methot to give direction the experimental studies as saving up time and money.

Kaynakça

  • [1] Wrigley, C.W., Bietz, J.A., Proteins and amino acids. In: Pomeranz,Y. (Ed.), Wheat—Chemistry and Technology, American Association of Cereal Chemistry, (1988); 1, 159–275.
  • [2] Wieser,H., Chemistry of gluten proteins, Food Microbiology, (2007); 24, 115–119.
  • [3] Shan, L.Molberg, Ø.Parrot, I.Hausch, F. Filiz, F. Gray, G.M. Sollid, L. M.Khosla, C. Structural Basis for Gluten Intolerance inCeliac Sprue. Science, (2002); 297, 2275−2279.
  • [4] Leung AY, Foster S. Monosodium glutamate. Encyclopedia of Common Natural Ingredients: Used in Food, Drugs, and Cosmetics (2nd Ed.). New York: Wiley, (2003);373-375.
  • [5] Onaolapo,A.Y., Onaolapo,O.J., Mosaku,T.J., Akanji,O.O., Abiodun,O., A Histological Study of the Hepatic and Renal Effects of Subchronic Low Dose Oral Monosodium Glutamate in Swiss Albino Mice, British Journal of Medicine & Medical Research,( 2013); 3(2): 294-306.
  • [6] John W.Olney,M.D.,Larance G.,SharpePh.D.,Ralph D.,Feigin,M.D., Glutamate-InducedBrain Damagein Infant Primates,Journal of Neuropathology&Experimental Neurology, (1972);31-3;464-488.
  • [7] Mehta, A.,Prabhakar,M., Kumar ,P., Deshmukh, r.,Sharma,P.L., Excitotoxicity: Bridge to Various Triggers in Neurodegenerative Disorders, Eur. J. Pharmacol., (2012); 698 (1-3), 6-18.
  • [8] Gökalp,F., A study on the chemical properties of eugenol and eugenol acetate, clove essential oils, Sigma J Eng & Nat Sci,(2016); 34 (3), 407-414.
  • [9] Gökalp,F., The Investıgatıon Thermodynamıcal Propertıes Of Carnosıc Acıd And Carnasol In Rosemary (Rosmarınusoffıcınalıs) By Usıng Hf (Hartre-Fock) As Theoretıcal, Sigma J Eng & Nat Sci, (2015); 33 (3), 417- 419.
  • [10] Yao,J., Luo,H., Wang,X., Understanding the Catalytic Mechanism and the Substrate Specificity of an Engineered Gluten Hydrolase by QM/MM Molecular Dynamics and Free Energy Simulations, J. Chem. Inf. Model,( 2017); 57, 1179−1186.
  • [11] Floris, F.M.,Filippi,C., Amovilli, C., A density functional and quantum Monte Carlo study of glutamic acid in vacuo and in a dielectric continuum medium, The Journal of Chemical Physics, (2012); 137-7, 075102.
  • [12] Nilesh, U. Jadhao, Anil B. Naik, Effect of electronegativity on structural, spectrophotometric and thermo-chemical properties of fluorine and chlorine substituted isoxazoles by DFT method, Cogent Chemistry ,(2017); 3: 1296342.
  • [13] Hansen,A.M., Rachel, R., Caspi, Glutamate joins the ranks of immunomodulators, Nat., Med., (2010);16(8): 856–858.
  • [14] Riedel, G., Platt, B., Micheau, J., Glutamate receptor function in learning and memory, Behav Brain Res.,(2003); 18;140(1-2):1-47.
  • [15] William, J., McEntee,Thomas, H., Crook, Glutamate: its role in learning, memory, and the aging brain, Psychopharmacology, (1993); 111-4, 391–401.
  • [16] Zhao, J., Verwer, R.W., van Wamelen, DJ., Q,i XR., Gao, S.F., Lucassen, P.J., Swaab, D.F.., Prefrontal changes in the glutamate-glutamine cycle and neuronal/glial glutamate transporters in depression with and without suicide, J Psychiatr Res.,(2016); 82:8-15.
  • [17] Li, C., Chai, S., Ju, Y., Hou, L., Zhao, H., Ma, W., Li, T., Sheng, J.5, Shi, W.., Pu-erh Tea Protects the Nervous System by Inhibiting the Expression of Metabotropic Glutamate Receptor 5, Mol. Neurobiol., (2017); 54(7):5286-5299.
Yıl 2017, Cilt: 35 Sayı: 4, 757 - 760, 01.12.2017

Öz

Kaynakça

  • [1] Wrigley, C.W., Bietz, J.A., Proteins and amino acids. In: Pomeranz,Y. (Ed.), Wheat—Chemistry and Technology, American Association of Cereal Chemistry, (1988); 1, 159–275.
  • [2] Wieser,H., Chemistry of gluten proteins, Food Microbiology, (2007); 24, 115–119.
  • [3] Shan, L.Molberg, Ø.Parrot, I.Hausch, F. Filiz, F. Gray, G.M. Sollid, L. M.Khosla, C. Structural Basis for Gluten Intolerance inCeliac Sprue. Science, (2002); 297, 2275−2279.
  • [4] Leung AY, Foster S. Monosodium glutamate. Encyclopedia of Common Natural Ingredients: Used in Food, Drugs, and Cosmetics (2nd Ed.). New York: Wiley, (2003);373-375.
  • [5] Onaolapo,A.Y., Onaolapo,O.J., Mosaku,T.J., Akanji,O.O., Abiodun,O., A Histological Study of the Hepatic and Renal Effects of Subchronic Low Dose Oral Monosodium Glutamate in Swiss Albino Mice, British Journal of Medicine & Medical Research,( 2013); 3(2): 294-306.
  • [6] John W.Olney,M.D.,Larance G.,SharpePh.D.,Ralph D.,Feigin,M.D., Glutamate-InducedBrain Damagein Infant Primates,Journal of Neuropathology&Experimental Neurology, (1972);31-3;464-488.
  • [7] Mehta, A.,Prabhakar,M., Kumar ,P., Deshmukh, r.,Sharma,P.L., Excitotoxicity: Bridge to Various Triggers in Neurodegenerative Disorders, Eur. J. Pharmacol., (2012); 698 (1-3), 6-18.
  • [8] Gökalp,F., A study on the chemical properties of eugenol and eugenol acetate, clove essential oils, Sigma J Eng & Nat Sci,(2016); 34 (3), 407-414.
  • [9] Gökalp,F., The Investıgatıon Thermodynamıcal Propertıes Of Carnosıc Acıd And Carnasol In Rosemary (Rosmarınusoffıcınalıs) By Usıng Hf (Hartre-Fock) As Theoretıcal, Sigma J Eng & Nat Sci, (2015); 33 (3), 417- 419.
  • [10] Yao,J., Luo,H., Wang,X., Understanding the Catalytic Mechanism and the Substrate Specificity of an Engineered Gluten Hydrolase by QM/MM Molecular Dynamics and Free Energy Simulations, J. Chem. Inf. Model,( 2017); 57, 1179−1186.
  • [11] Floris, F.M.,Filippi,C., Amovilli, C., A density functional and quantum Monte Carlo study of glutamic acid in vacuo and in a dielectric continuum medium, The Journal of Chemical Physics, (2012); 137-7, 075102.
  • [12] Nilesh, U. Jadhao, Anil B. Naik, Effect of electronegativity on structural, spectrophotometric and thermo-chemical properties of fluorine and chlorine substituted isoxazoles by DFT method, Cogent Chemistry ,(2017); 3: 1296342.
  • [13] Hansen,A.M., Rachel, R., Caspi, Glutamate joins the ranks of immunomodulators, Nat., Med., (2010);16(8): 856–858.
  • [14] Riedel, G., Platt, B., Micheau, J., Glutamate receptor function in learning and memory, Behav Brain Res.,(2003); 18;140(1-2):1-47.
  • [15] William, J., McEntee,Thomas, H., Crook, Glutamate: its role in learning, memory, and the aging brain, Psychopharmacology, (1993); 111-4, 391–401.
  • [16] Zhao, J., Verwer, R.W., van Wamelen, DJ., Q,i XR., Gao, S.F., Lucassen, P.J., Swaab, D.F.., Prefrontal changes in the glutamate-glutamine cycle and neuronal/glial glutamate transporters in depression with and without suicide, J Psychiatr Res.,(2016); 82:8-15.
  • [17] Li, C., Chai, S., Ju, Y., Hou, L., Zhao, H., Ma, W., Li, T., Sheng, J.5, Shi, W.., Pu-erh Tea Protects the Nervous System by Inhibiting the Expression of Metabotropic Glutamate Receptor 5, Mol. Neurobiol., (2017); 54(7):5286-5299.
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Mühendislik
Bölüm Research Articles
Yazarlar

Faik Gökalp Bu kişi benim 0000-0003-4363-3839

Yayımlanma Tarihi 1 Aralık 2017
Gönderilme Tarihi 21 Ağustos 2017
Yayımlandığı Sayı Yıl 2017 Cilt: 35 Sayı: 4

Kaynak Göster

Vancouver Gökalp F. A NEW APPROACH OF GLUTEN DERIVATIVES FOR ACTIVITY AS THEORETICAL. SIGMA. 2017;35(4):757-60.

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