A promising marker for carotid artery disease: Monocyte to high-density lipoprotein ratio (MHR)

Abstract

Objectives: The aim of our study was to evaluate the relation between monocyte/high-density lipoprotein(HDL) ratio value and carotid artery stenosis in patients who underwent carotid angiography.

Methods: To our study, 94 participants were enrolled (68 patients, 26 healthy individuals) who attended the cardiovascular surgery policlinic and had carotid angiography in between January 2017 and June 2018. Participants were divided into two groups, who have carotid artery disease and who don't. Peripheral venous blood results, taken from all patients before angiography for hematologic examination, were evaluated. Groups were compared according to their monocyte/high-density lipoprotein(HDL)  values and other hematologic results.

Results: Monocyte/high-density lipoprotein(HDL) ratio values were found to be higher in the group with a carotid artery disease compared to the group with a normal carotid angiography (72±10 ver 68±11  p=0.063). Yet again when the two groups were compared, there were differences with respect to existing hypertension, existing diabetes and gender (p=0.034, p=0.043, p=0.035 respectively).

Conclusion: In our study, it was shown that high monocyte/high-density lipoprotein(HDL) ratio value can be a predictor for the diagnosis of carotid artery disease.

Keywords

• Carotid artery disease,Atherosclerosis risk factors,Monocyte/high-density lipoprotein(HDL) ratio

Karotis Arter Hastalığı İçin Ümit Verici Bir Marker: Monositin High Density Lipoproteine Oranı (MHR)

Abstract

Giriş: Çalışmamızın amacı karotis arter angiografisi yapılan hastalarda MHR (monosit/HDL ratio) değerlerinin karotis arter stenozu ile ilişkisini retrospektif olarak araştırmaktı.

Gereç ve Yöntemler: Çalışmamıza ocak 2017 ile haziran 2018 yılları arasında kardiyoloji ve kalp ve damar cerrahisi polikliniğine başvuran karotis arter angiografisi yapılan 94 (68 hasta, 26 sağlıklı) hasta dahil edildi. Karotis arter hastalığı olanlar ve olmayanlar diye iki gruba ayrıldı. Tüm hastaların hematolojik değerlerine bakılması için angiografi öncesi alınan periferik venöz kan sonuçları tarandı. Gruplar MHR değeri ve diğer hematolojik sonuçlar açısından karşılaştırıldı.

Bulgular: MHR değeri karotis arter hastalığı olanlar grubunda karotis arter angiografisi normal çıkan gruba göre anlamlı olarak yüksek bulundu (68±11 ver 721±10, p=0.063). Yine iki grup kıyaslandığında hipertansiyon, diabetus mellitus varlığı ve cinsiyet açısından gruplar arasında farklılk vardı ( p=0,034,p=0,043,p=0,035,sırası ile).

Sonuç: Çalışmamızda yüksek MHR değerinin karotis arter hastalığı tanısında bir öngördürücü olabileceği gösterildi.

Keywords

• Karotis arter hastalığı,Monosit/HDL oranı(MHR),Aterosklerotik risk faktörleri

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