A Review on the Antidiabetic Potential of Saffron in the Treatment of Type 2 Diabetes Mellitus and Its Research Methodologies
Öz
This study is a review of the antidiabetic potential of the Saffron plant in the treatment of Type 2 Diabetes and research methodologies. The experimental design of this project study aimed to obtain crocin from the saffron plant. Crocin is considered a potential natural drug agent thanks to its high antioxidant and antidiabetic properties. However, in order to obtain the highest yield of crocin in obtaining this natural agent, it is very important to ensure optimization by selecting the right extraction techniques, phenolic content, antioxidant and antidiabetic analyses. In this project, it was aimed to apply extraction techniques under appropriate conditions to obtain crocin from the Crocus sativus plant, also known as saffron. In addition, an experimental design was created to apply HPLC to obtain high purity of crocin, TPC analysis to determine total phenolic content, ORAC and DPPH analyses to determine antioxidant capacity, and α-Amylase Inhibition Test and α-Glucosidase Inhibition Test techniques to determine antidiabetic potential. Once the desired results are achieved, experimental studies will be initiated to develop crocin into a natural market drug.
Anahtar Kelimeler
Kaynakça
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