EN
INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON
Öz
Age-related macular degeneration (AMD) is a non-recyclable visual disorder among elderly people worldwide and AMD is one of the leading causes of blindness. Former studies, interleukins were found to be effective in patients with AMD. This study’s object, the relationship of serum interleukin 17 with age-related macular degeneration was evaluated.
Interleukin 17 levels were measured by ELISA method using the blood sera of 100 patients diagnosed with age-related macular degeneration and 100 healthy individuals in the control group.
Acording to the results of the study, the differences between the patient and control groups of interleukin 17 levels was found statistically significant (p:0,001; p > 0,05). It was found that gender difference in patients did not affect interleukin 17 levels (p=0,649; p > 0,05).
In the study, there was a significant relationship between age-related macular degeneration and serum interleukin 17.
Anahtar Kelimeler
Kaynakça
- Referans1 Ardeljan D, Wang Y, Park S, Shen D, Chu XK, Yu CR, et al. Interleukin-17 Retinotoxicity Is Prevented by Gene Transfer of a Soluble Interleukin-17 Receptor Acting as a Cytokine Blocker: Implications for Age-Related Macular Degeneration. Plos One. 2014;9(4), e95900.
- Referans2 Batman C, ve Çalış F. Yaş Tip (Neovasküler) Yaşa Bağlı Makula Dejenerasyonunda Cerrahi Tedavi. Guncel Retina. 2017;1(3), 229-234.
- Referans3 Bojanowski CM, Tuo J, Chew EY, Csaky KG, and Chan CC. Analysıs Of Hemıcentın-1, Hogg1, And E-Selectın Sıngle Nucleotıde Polymorphısms In Age-Related Macular Degeneratıon. Trans Am Ophthalmol Soc. 2005;103, 37-45. Referans4 Buschini E, Fea AM, Lavia CA, Nassisi M, Pignata G, Zola M, et al. Recent developments in the management of dry age-related macular degeneration. Clinical Ophthalmology. 2015; 9, 563–574.
- Referans5 Canter JA, Olson LM, Spencer K, Boutaud Schnetz N, Anderson B, Hauser MA, et al. Mitochondrial DNA Polymorphism A4917G Is Independently Associated with Age-Related Macular Degeneration. Plos One. 2008; 3(5), e2091.
- Referans6 Ferrara D, Silver RE, Louzada RN, Novais EA, Collins GK, and Seddon JM. Optical coherence tomography features preceding the onset of advanced age-related macular degeneration. Invest Ophthalmol Vis Sci. 2017;58(9), 3519-3529.
- Referans7 Hallak JA, Sisternes L, Osborne A, Yaspan B, Rubin DL, and Leng T. Imaging, Genetic, and Demographic Factors Associated With Conversion to Neovascular Age-Related Macular Degeneration: Secondary Analysis of a Randomized Clinical Trial. JAMA Ophthalmol. 2019; 137(7):738-744.
- Referans8 Komiyama Y, Nakae S, Matsuki T, Nambu A, Ishigame H, Kakuta S, et al. IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis. The Journal of Immunology. 2006;177, 566-573.
- Referans9 Liu B, Wei L, Meyerle C, Tuo J, Sen HN, Li Z, Chakrabarty S, et al. Complement component C5a Promotes Expression of IL-22 and IL-17 from Human T cells and its Implication in Age-related Macular Degeneration. Journal of Translational Medicine. 2011;9(111), 1-12.
Ayrıntılar
Birincil Dil
İngilizce
Konular
Klinik Tıp Bilimleri
Bölüm
Klinik Araştırma
Yayımlanma Tarihi
31 Ağustos 2022
Gönderilme Tarihi
20 Temmuz 2022
Kabul Tarihi
16 Ağustos 2022
Yayımlandığı Sayı
Yıl 2022 Cilt: 4 Sayı: 2
APA
Türker Aslan, H., & Ateş, Ö. (2022). INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON. Sabuncuoglu Serefeddin Health Sciences, 4(2), 9-16. https://doi.org/10.55895/sshs.1145995
AMA
1.Türker Aslan H, Ateş Ö. INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON. Sabuncuoglu Serefeddin Health Sciences. 2022;4(2):9-16. doi:10.55895/sshs.1145995
Chicago
Türker Aslan, Hatice, ve Ömer Ateş. 2022. “INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON”. Sabuncuoglu Serefeddin Health Sciences 4 (2): 9-16. https://doi.org/10.55895/sshs.1145995.
EndNote
Türker Aslan H, Ateş Ö (01 Ağustos 2022) INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON. Sabuncuoglu Serefeddin Health Sciences 4 2 9–16.
IEEE
[1]H. Türker Aslan ve Ö. Ateş, “INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON”, Sabuncuoglu Serefeddin Health Sciences, c. 4, sy 2, ss. 9–16, Ağu. 2022, doi: 10.55895/sshs.1145995.
ISNAD
Türker Aslan, Hatice - Ateş, Ömer. “INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON”. Sabuncuoglu Serefeddin Health Sciences 4/2 (01 Ağustos 2022): 9-16. https://doi.org/10.55895/sshs.1145995.
JAMA
1.Türker Aslan H, Ateş Ö. INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON. Sabuncuoglu Serefeddin Health Sciences. 2022;4:9–16.
MLA
Türker Aslan, Hatice, ve Ömer Ateş. “INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON”. Sabuncuoglu Serefeddin Health Sciences, c. 4, sy 2, Ağustos 2022, ss. 9-16, doi:10.55895/sshs.1145995.
Vancouver
1.Hatice Türker Aslan, Ömer Ateş. INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON. Sabuncuoglu Serefeddin Health Sciences. 01 Ağustos 2022;4(2):9-16. doi:10.55895/sshs.1145995