Araştırma Makalesi

COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN

Cilt: 7 Sayı: 1 30 Nisan 2025
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COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN

Öz

This study aimed to examine the levels of 25 hydroxy vitamin D (25-OH D) in preeclampsia and normotensive pregnant groups. A total of 70 pregnant women who came to the Health Sciences University, Istanbul Gaziosmanpasa Training and Research Hospital for delivery at 35-40 weeks of gestation were included in the study. The study group consisted of 35 preeclamptic (n=35) and 35 normotensive (n=35) pregnant women. Demographic, obstetric, and laboratory results of the two groups were compared in terms of 25-OH D levels. There was no statistically significant difference with the control group in terms of maternal age, gestational age at birth, gravidity, parity, number of abortions and living children, and BMI (p>0.05). When the mean diastolic blood pressure and systolic blood pressure of the groups were compared, the mean blood pressure of the individuals in the preeclamptic group was found to be statistically and significantly higher than the mean systolic and diastolic blood pressure of the individuals in the control group (p<0.05). When the groups were compared in terms of LFT (ALT, AST), proteinuria in urine, and platelet levels in blood, no statistically significant difference was found between the groups. Vitamin D levels were found to be statistically significantly lower in preeclamptic pregnancies compared to normotensive pregnancies. Low maternal vitamin D levels may play a role in the etiology of essential hypertension and preeclampsia, and more comprehensive research is needed on the potential positive effects of additional vitamin D supplementation.

Anahtar Kelimeler

Kaynakça

  1. Andersen, L. B., Przybyl, L., Haase, N., von Versen‐Höynck, F., Qadri, F., Jørgensen, J. S., Sorensen, G. L., Fruekilde, P., Poglitsch, M., ve Szijarto, I. (2015). Vitamin D depletion aggravates hypertension and target‐organ damage. Journal of the American heart association, 4(2), e001417.
  2. Aslan, D. D., Ohanoğlu, K., Ceylan, M. K., ve Verit, F. F. (2022). Does Vitamin D Status Alter the Severity af Preeclampsia? A Single-Center Case-Control Study. Medical Records, 4(3), 328-332.
  3. Bakacak, M., Serin, S., Ercan, O., Köstü, B., Avci, F., Kılınç, M., Kıran, H., ve Kiran, G. (2015). Comparison of Vitamin D levels in cases with preeclampsia, eclampsia and healthy pregnant women. International journal of clinical and experimental medicine, 8(9), 16280.
  4. Baker, A. M., Haeri, S., Camargo Jr, C. A., Espinola, J. A., ve Stuebe, A. M. (2010). A nested case-control study of midgestation vitamin D deficiency and risk of severe preeclampsia. The Journal of Clinical Endocrinology & Metabolism, 95(11), 5105-5109.
  5. Bärebring, L., Bullarbo, M., Glantz, A., Leu Agelii, M., Jagner, Å., Ellis, J., Hulthén, L., Schoenmakers, I., ve Augustin, H. (2016). Preeclampsia and blood pressure trajectory during pregnancy in relation to vitamin D status. PloS one, 11(3), e0152198.
  6. Bodnar, L. M., Catov, J. M., Simhan, H. N., Holick, M. F., Powers, R. W., ve Roberts, J. M. (2007). Maternal vitamin D deficiency increases the risk of preeclampsia. The Journal of Clinical Endocrinology & Metabolism, 92(9), 3517-3522.
  7. Gholami, H., Fayazi, S., Shirshekan, M., Motamed, N., ve Tofighi, S. (2022). Comparison of serum level of vitamin D in pregnant women with preeclampsia and a control group in Ayatollah Mousavi hospital in Zanjan. Journal of Obstetrics, Gynecology and Cancer Research, 7(4), 335-340.
  8. Haugen, M., Brantsæter, A. L., Trogstad, L., Alexander, J., Roth, C., Magnus, P., ve Meltzer, H. M. (2009). Vitamin D supplementation and reduced risk of preeclampsia in nulliparous women. Epidemiology, 20(5), 720-726.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri (Diğer)

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

30 Nisan 2025

Gönderilme Tarihi

8 Kasım 2024

Kabul Tarihi

13 Mart 2025

Yayımlandığı Sayı

Yıl 2025 Cilt: 7 Sayı: 1

Kaynak Göster

APA
Demir Özkan, M., Salman, S., Balcı, M. F., Öktem, A., Şanlı, M., Alan, Y., & Alan, M. (2025). COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN. Sabuncuoglu Serefeddin Health Sciences, 7(1), 11-16. https://doi.org/10.55895/sshs.1688229
AMA
1.Demir Özkan M, Salman S, Balcı MF, vd. COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN. Sabuncuoglu Serefeddin Health Sciences. 2025;7(1):11-16. doi:10.55895/sshs.1688229
Chicago
Demir Özkan, Merve, Süleyman Salman, Mücahit Furkan Balcı, vd. 2025. “COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN”. Sabuncuoglu Serefeddin Health Sciences 7 (1): 11-16. https://doi.org/10.55895/sshs.1688229.
EndNote
Demir Özkan M, Salman S, Balcı MF, Öktem A, Şanlı M, Alan Y, Alan M (01 Nisan 2025) COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN. Sabuncuoglu Serefeddin Health Sciences 7 1 11–16.
IEEE
[1]M. Demir Özkan vd., “COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN”, Sabuncuoglu Serefeddin Health Sciences, c. 7, sy 1, ss. 11–16, Nis. 2025, doi: 10.55895/sshs.1688229.
ISNAD
Demir Özkan, Merve - Salman, Süleyman - Balcı, Mücahit Furkan - Öktem, Abdulmecit - Şanlı, Mustafa - Alan, Yasemin - Alan, Murat. “COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN”. Sabuncuoglu Serefeddin Health Sciences 7/1 (01 Nisan 2025): 11-16. https://doi.org/10.55895/sshs.1688229.
JAMA
1.Demir Özkan M, Salman S, Balcı MF, Öktem A, Şanlı M, Alan Y, Alan M. COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN. Sabuncuoglu Serefeddin Health Sciences. 2025;7:11–16.
MLA
Demir Özkan, Merve, vd. “COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN”. Sabuncuoglu Serefeddin Health Sciences, c. 7, sy 1, Nisan 2025, ss. 11-16, doi:10.55895/sshs.1688229.
Vancouver
1.Merve Demir Özkan, Süleyman Salman, Mücahit Furkan Balcı, Abdulmecit Öktem, Mustafa Şanlı, Yasemin Alan, Murat Alan. COMPARISON OF MATERNAL SERUM VITAMIN D LEVELS IN PREECLAMPTIC AND HEALTHY PREGNANT WOMEN. Sabuncuoglu Serefeddin Health Sciences. 01 Nisan 2025;7(1):11-6. doi:10.55895/sshs.1688229

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