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Drug and addictive substance poisoning with medical pharmacologist assessment

Cilt: 2 Sayı: 1 24 Şubat 2020
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Drug and addictive substance poisoning with medical pharmacologist assessment

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Purpose: Poisoning is a medical emergency that represent a major health problem all over the world. The rate of poisoning with prescription and non-prescription drugs, and addictive substances are increasing day by day. Methods: This paper summarizes drugs and addictive substances that often cause poisoning in 2017 and their pharmacological properties. Results: Among all the poisonings, drug poisonings were the first in adults and third in children age 5 years or less. Analgesics were the most common drug poisoning in both populations. Considering the etiology of drug poisoning, the ranking is as follows: sedative-hypnotics/ antipsychotics, opioids and other addictive substances, alcohols, calcium channel blockers and acetaminophen (paracetamol). Amphetamines were the most frequent poisoning substances in addictive substances. Analgesics are the cause of poisoning that results in death at age 5 or less. Major conclusions: Although paracetamol, one of the analgesics, which is sold over the counter, ranks 6th among the fatal poisonings, it is in the first place among drug poisonings in all age groups, probably because of its easy access and cheapness.

Anahtar Kelimeler

Kaynakça

  1. Referans1. Baselt RC. Disposition of Toxic Drugs and Chemicals in Man, 7th, Biomedical Publications, Fost er City 2004.
  2. Referans2. Chiang WK. Amphetamines. In: Goldfrank’s Toxicologic Emergencies, 9th, Goldfrank LR (Ed), M cGraw-Hill, New York 2011. p.1078.
  3. Referans3. Clark R, Fisher JE, Sketris IS, Johnston GM. Population prevalence of high dose paracetamol in dispensed paracetamol/opioid prescription combinations: an observational study. BMC Clin Pharmacol 2012; 12:11.
  4. Referans4. Clinical toxicology course, Clinical Toxicology Study Group of Turkish Pharmacology Society, 06-07 December 2018, Istanbul/Turkey.
  5. Referans5. Eisenberg MJ, Brox A, Bestawros AN. Calcium channel blockers: an update. Am J Med 2004; 116:35.
  6. Referans6. Forrest JA, Clements JA, Prescott LF. Clinical pharmacokinetics of paracetamol. ClinPharmacokinet 1982; 7:93.
  7. Referans7. Gummin DD, Mowry JB, Spyker DA, Brooks DE, Osterthaler KM, Banner W. 2017 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 35th Annual Report, Clin Toxicol (Phila). 2018 Dec;56(12):1213-1415. doi: 10.1080/15563650.2018.1533727.
  8. Referans8. Jaeschke H, McGill MR, Ramachandran A. Oxidant stress, mitochondria, and cell deathmechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity.Drug Metab Rev 2012; 44:88.

Ayrıntılar

Birincil Dil

İngilizce

Konular

-

Bölüm

Konferans Bildirisi

Yayımlanma Tarihi

24 Şubat 2020

Gönderilme Tarihi

20 Ekim 2019

Kabul Tarihi

8 Şubat 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 2 Sayı: 1

Kaynak Göster

APA
Jafarova Demirkapu, M. (2020). Drug and addictive substance poisoning with medical pharmacologist assessment. Sabuncuoglu Serefeddin Health Sciences, 2(1), 40-54. https://izlik.org/JA82WL74AZ
AMA
1.Jafarova Demirkapu M. Drug and addictive substance poisoning with medical pharmacologist assessment. Sabuncuoglu Serefeddin Health Sciences. 2020;2(1):40-54. https://izlik.org/JA82WL74AZ
Chicago
Jafarova Demirkapu, Mahluga. 2020. “Drug and addictive substance poisoning with medical pharmacologist assessment”. Sabuncuoglu Serefeddin Health Sciences 2 (1): 40-54. https://izlik.org/JA82WL74AZ.
EndNote
Jafarova Demirkapu M (01 Şubat 2020) Drug and addictive substance poisoning with medical pharmacologist assessment. Sabuncuoglu Serefeddin Health Sciences 2 1 40–54.
IEEE
[1]M. Jafarova Demirkapu, “Drug and addictive substance poisoning with medical pharmacologist assessment”, Sabuncuoglu Serefeddin Health Sciences, c. 2, sy 1, ss. 40–54, Şub. 2020, [çevrimiçi]. Erişim adresi: https://izlik.org/JA82WL74AZ
ISNAD
Jafarova Demirkapu, Mahluga. “Drug and addictive substance poisoning with medical pharmacologist assessment”. Sabuncuoglu Serefeddin Health Sciences 2/1 (01 Şubat 2020): 40-54. https://izlik.org/JA82WL74AZ.
JAMA
1.Jafarova Demirkapu M. Drug and addictive substance poisoning with medical pharmacologist assessment. Sabuncuoglu Serefeddin Health Sciences. 2020;2:40–54.
MLA
Jafarova Demirkapu, Mahluga. “Drug and addictive substance poisoning with medical pharmacologist assessment”. Sabuncuoglu Serefeddin Health Sciences, c. 2, sy 1, Şubat 2020, ss. 40-54, https://izlik.org/JA82WL74AZ.
Vancouver
1.Mahluga Jafarova Demirkapu. Drug and addictive substance poisoning with medical pharmacologist assessment. Sabuncuoglu Serefeddin Health Sciences [Internet]. 01 Şubat 2020;2(1):40-54. Erişim adresi: https://izlik.org/JA82WL74AZ

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