Metimazole Bağlı Vaskülit Gelişen Hashitoksikozisli Adölesan Hasta

Yıl 2018, Cilt: 12 Sayı: 1, 0 - 0, 01.04.2018

Derya Buluş Elif Yağlı Bahar Büyükkaragöz

Öz

Birçok ülkede, çocuklarda hipertiroidizmde ilk seçenek tedavi metimazoldür. Metimazol ile tedavi sırasında bazı yan etkiler görülebilir. Sık görülen yan etkiler döküntü, kaşıntı, artralji, bulantı ve tat değişikliğidir. Diğer ciddi yan etkileri Steven Johnson Sendromu, trombositopeni, nötropeni ve vaskülittir. Burada; metimazole bağlı vaskülit gelişen16 yaşındaki kız hastayı tartışacağız. Hastamızda metimazole bağlı vaskülit tedaviden sonraki birinci ayda görülmüştür. Vaskülit semptomları tedavi kesiminden sonra hızlıca kaybolmuştur. Vaskülit metimazolün ağır bir yan etkisidir ve tedavi kesilmesini gerekmektedir.

Anahtar Kelimeler

Adölesan, Hipertiroidi, Metimazol, Vaskülit

Vasculitis Caused by Methimazole in an Adolescent Patient with Hashitoxicosis

Öz

Methimazole therapy is the first-line treatment in children with hyperthyroidism in many countries. Treatment with methimazole may be accompanied by side effects. Common side effects include rash, pruritus, arthralgia, nausea, and reduced taste. Other serious side effects include the Stevens-Johnson Syndrome, thrombocytopenia, neutropenia, and vasculitis. Here, we report a 16-year-old girl with methimazole-induced vasculitis. The onset of vasculitis in our patient was one month after the initiation of methimazole therapy. The symptoms of vasculitis disappeared rapidly following cessation of treatment. Vasculitis is a serious side effect of methimazole and is an indication for prompt cessation of treatment

Anahtar Kelimeler

Adolescent, Hyperthyroidism, Methimazole, Vasculitis

Kaynakça

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