Orbital tumors

Öz

Various developmental abnormalities, inflammatory disorders and systemic disorders also involving the ocular muscles can be encountered in the orbit as well as true neoplasms, cysts and other tumoral lesions. Orbital tumors may be primary or secondary. A different tumor spectrum is encountered in adults and children. Choristomas, tumors of various mesenchymal tissues, epithelial neoplasms of the lacrimal tissues, lymphoid neoplasms and miscellaneous tumors occur in the orbit. Additionally, the tumors of adjacent anatomical structures may involve the orbit and metastatic tumors arising from various body sites may be noted in the orbital tissues. Differences may exist between the data of orbital tumor series from various countries owing to the geographic and socio-cultural factors

Anahtar Kelimeler

• Orbit, tumor, neoplasm

Prof. Dr. Nejat Sabuncu Konferansı: Orbital tümörler

Öz

Orbital bölgede çeşitli gelişimsel anomaliler, yangısal hastalıklar ve oküler kasları da tutan sistemik hastalıklar yanı sıra; gerçek neoplazmlar, kistler ve diğer tümöral lezyonlar da izlenebilmektedir. Orbital tümörler primer ya da sekonder olabilirler. Çocuklarda ve erişkinlerde farklı bir orbital tümör spektrumu görülür. Orbitada, koristomalar, çeşitli mezenkimal doku tümörleri, lakrimal dokuların epitelial tümörleri, lenfoid neoplazmlar ve diğer çeşitli tümörlere rastlanabilir. Ek olarak, komşu anatomik yapıların tümörleri orbitayı sekonder olarak tutabilirler. Ayrıca, değişik vücut bölgelerinde gelişen tümörlerin metastazlarına da orbitada rastlanabilir. Coğrafi ve sosyo-kültürel nedenlere bağlı olarak değişik ülkelerdeki orbital lezyon serilerindeki veriler arasında farklılıklar bulunabilir

Anahtar Kelimeler

• Orbita, tümör, neoplazm

Kaynakça

1. Scroggs MW, Klinworth GK. Normal Eye and Ocular Adnexa. In: Histology for Pathologists, Sternberg SS, ed. New York: Raven Press, 1992; 903-924
2. Yanoff M, Fine BS. Ocular Pathology. 5th Ed, Thailand: Mosby, 2002; 511-575.
3. Jakobiec FA, Bilyk JR, Font RL. Orbit. In: Ophthalmic Pathology, Spencer WH Ed. Vol IV, 4th Ed, U.S.A.: W.B. Saunders, 1996; 2438-2934.
4. Canda MŞ, Özkara E, Tuna B, Gökden N. Orbital tümörlerin patolojisi (9 olgu). Türkiye Ekopatoloji Dergisi, 1997; 3 (1-2): 32-34.
5. Eagle RC. The Eye. In: Principles and Practice of Surgical Pathology and Cytopathology, Silverberg SS, DeLellis RA, Frable WJ, eds, Vol III, 3rd Ed, Singapore: Churchill Livingstone, 1997; 2857-2903.
6. Johansen S, Heegard S, Bogeskov L, Prause JU. Orbital space occupying lesions in Denmark 1974-1997. Acta Opththalmol Scand 2000; 78: 547-552.
7. Günalp I, Gündüz K. Pediatric orbital tumors in Turkey. Ophthalmol Plast Reconstr Surg 1995; 11 (3): 193-9.
8. Ni C, Ma X, Histopathologic classification of 1921 orbital tumors. Yan Ke Xue Bao. 1995; 11 (2): 101-4.

9. Demirkesen C, Kaner G. Konjenital orbital teratom: Bir vaka bildirisi. Türk Patoloji Dergisi, 1994; 10 (1): 73-74.
10. Günalp I, Duruk K, Gündüz K. Orbital rhabdomyosarcoma: a twenty-year survey in Turkey. Jpn J Ophthalmol 1993; 37 (4): 499-504.
11. Cantore WA. Neural orbital tumors. Curr Opin Ophthalmol 2000; 11: 367-371.
12. Konrad EA, Thiel HJ. Schwannoma of the orbit.
13. Opthalmologica, 1984; 188: 118-127.
14. Tsuzuki N, Katoh H, Ohnuki A, Ishihara S, Miyazawa T, Nawashiro H, Shima K. Cystic schwannoma of the orbit: Case report. Surg Neurol 2000; 54: 385-7.
15. Khwarg SI, Lucarelli MJ, Lemke BN, Smith ME, Alber DM. Ancient schwannoma of the orbit. Arch Opthalmol. 1999; 117: 262-64.
16. Günalp I, Gündüz K, Duruk K, Kanpolat Y. Neurogenic tumors of the orbit. Jpn J Ophthalmol 1994; 38 (2): 185-90.
17. Font RL, Smith SL, Bryan RG. Malignant epithelial tumors of the lacrimal gland. Arch Ophthalmol. 1998; 116: 613-616.
18. Ni C, Kuo PK, Dryja TP. Histopathological classification of 272 primary epithelial tumors of the lacrimal gland. Chin Med J 1992; 105 (6): 481-5.
19. Lauer SA. Ocular adnexal lymphoid tumors. Curr Opin Ophthalmol 2000; 11: 361-366.
20. Sharara N, Holden JT, Wojno TH, Feinberg AS,
21. Grossniklaus HE. Ocular adnexal lymphoid proliferations. Clinical, histologic, flow cytometric and molecular analysis of forty-three cases. Ophthalmology 2003; 110: 1245-54.
22. Shields JA, Shields CL. Orbital malignant melanoma: The 2002 Sean B. Murphy lecture. Opthal Plast Reconstr Surg 2003; 19 (4): 262-269.
23. Günalp I, Gündüz K. Metastatic orbital tumors. Jpn J Ophthalmol 1995; 39 (1): 65-70.