Acute effects of different exercises on hemodynamic responses and fatigue in Duchenne muscular dystrophy

Yıl 2012, Cilt: 23 Sayı: 1, 10 - 16, 01.04.2012

Öz

Anahtar Kelimeler

-

Duchenne musküler distrofide farklı egzersizlerin hemodinamik cevaplar ve yorgunluk üzerine akut etkileri

Öz

Amaç: Çalışmanın amacı, Duchenne musküler distrofi (DMD)’de farklı egzersiz tiplerinin hemodinamik yanıtlar ve yorgunluk üzerine akut etkilerinin araştırılmasıydı. Yöntem: Çalışmaya erken dönemdeki 30 DMD’li çocuk dahil edildi. Çocuklara seçilen üç farklı tipte egzersizden biri yalnızca tek bir seans uygulandı. Bunlar üç dakika merdiven çıkıp-inme, 40 dakika bisiklet sürme ve 40 dakika fizyoterapist eşliğinde üst ve alt ekstremiteler için germe-kuvvetlendirme-aerobik egzersizleri içeren bir program idi. Kalp hızı, oksijen satürasyonu, kas kuvveti ve yorgunluk değerlendirmeleri ile süreli performans testlerini içeren egzersizin akut etkilerini gösteren ölçümler egzersizlerden önce ve sonra yapıldı. Çocuklarda egzersiz sonrası oluşan yorgunluğun günlük aktivite performansına yansıması anket yardımı ile değerlendirildi. Sonuçlar: Merdiven çıkıp-inme ve fizyoterapi egzersizleri sonrasında kalp hızının arttığı bulundu (p

Anahtar Kelimeler

Duchenne musküler distrofi , Kas kuvveti , Egzersiz , Hemodinami

Kaynakça

• Biggar WD, Klamut HJ, Demacio PC, et al. Duchenne muscular dystrophy: current knowledge, treatment, and future prospects. Clin Orthop Relat Res. 2002;40:88-106.
• Dubowitz V. Muscle Disorders in Childhood. 2nd ed. Philadelphia: W. B. Saunders Company Ltd; 1995.
• Kalkman JS, Schillings ML, Zwarts MJ, et al. The development of a model of fatigue in neuromuscular disorders: a longitudinal study. J Psychosom Res. 2007;62:571-579.
• Phillips BA, Mastaglia FL. Exercise therapy in patients with myopathy. Curr Opin Neurol. 2000;13:547-552.
• Sveen ML, Jeppesen TD, Hauerslev S, et al. Endurance training improves fitness and strength in patients with Becker muscular dystrophy. Brain. 2008;131:2824-2831.
• Brooke MH, Griggs RC, Mendell JR, et al. Clinical trial in Duchenne dystrophy. 1. The design of the protocol. Muscle Nerve. 1981;4:186-197.
• Yelling M, Lamb K, Swaine I. Validity of a pictorial perceived exertion scale for effort estimation and effort production during stepping exercise in adolescent children. Eur Phys Educ Rev. 2002;8:157- 175.
• Cuthbert SC, Goodheart GJ Jr. Research supporting the reliability of the manual muscle test. Chiropr Osteopat. 2007;15:4.
• Marchesi C, Main M, Kinali M, et al. Correlation of hand-held myometry with alternative methods of assessment of muscle strength and function in DMD patients. Neuromuscul Disord. 2008;18:724-833.
• Bushby K, Muntoni F, Urtizberea A, et al. Workshop report: Report on the 124th ENMC International Workshop. Treatment of Duchenne muscular dystrophy; defining the gold standards of management in the use of corticosteroids 2–4 April 2004, Naarden, The Netherlands. Neuromuscul Disord. 2004;14:526–534.
• Merkies IS, Faber CG. Outcome measures in Duchenne muscular dystrophy: are we ready for the new therapeutic era?. Neuromuscul Disor. 2009;19:447.
• Reck MOTOmed Movement Therapy Systems. RECK-Technik GmbH & Co. KG Reckstrasse 1- 588422 Betzenweiler, Germany. Erişim: 16.12.2009, http://www.motomed.com
• Cup EH, Pieterse AJ, Knuijt S. Referral of patients with neuromuscular disease to occupational therapy, physical therapy and speech therapy: usual practice versus multidisciplinary advice. Disabil Rehabil. 2007;29:717-726.
• Green SB, Salkind NJ, Akey TM. Using SPSS for Windows: Analyzing and Understanding Data.2nd ed. New Jersey: Prentice Hall; 2000.
• Rodillo E, Fernandez-Bermejo E, Heckmatt JZ, et al. Prevention of rapidly progressive scoliosis in Duchenne muscular dystrophy by prolongation of walking with orthoses. J Child Neurol. 1988;3:269- 274.
• Newsom-Davis J. The respiratory system in muscular dystrophy. Br Med Bull. 1980;36:135-138.
• Rodillo E, Noble-Jamieson CM, Aber V, et al. Respiratory muscle training in Duchenne muscular dystrophy. Arch Dis Child. 1989;64:736-738.
• Stern LM, Martin AJ, Jones N, et al. Training inspiratory resistance in Duchenne dystrophy using adapted computer games. Dev Med Child Neurol. 1989;31:494-500.
• Inkley SR, Oldenburg FC, Vignos PJ Jr. Pulmonary function in Duchenne muscular dystrophy related to stage of disease. Am J Med. 1974;56:297-306.
• Wanke T, Toifl K, Merkle M, et al. Inspiratory muscle training in patients with Duchenne muscular dystrophy. Chest. 1994;105:475-482.
• Wade CK, Cargan AL, Diamond BE, et al. Pharmacologic interventions to mitigate dystrophin deficiencies. Ann Neurol. 1995;38:522.
• Aboussouan LS. Mechanisms of exercise limitation and pulmonary rehabilitation for patients with neuromuscular disease. Chron Respir Dis. 2009;6:231-249.
• Abresch RT, Han JJ, Carter GT. Rehabilitation management of neuromuscular disease: the role of exercise training. Neuromuscul Disease. 2009;11:7- 21.
• Allen DG. Skeletal muscle function: role of ionic changes in fatigue, damage and disease. Clin Exp Pharmacol Physiol. 2004;31:485-493.
• Lindeman E, Leffers P, Reulen J, et al. Quadriceps strength and timed motor performance in myotonic dystrophy, Charcot-Marie-Tooth disease and healthy subjects. Clin Rehabil. 1998;12:127-135.