Antimikrobiyal Potansiyele Sahip Kalkonların Bibliyometrik Analizi

Öz

ÖZET: Amaç: Kalkonlar, bitkilerde doğal olarak bulunan, insan ve hayvan vücudunda sentezlenemeyen sekonder metabolitlerdir. Yapısı 1,3-diaril-2-propen-1-on olup flavonoidlerin öncüsüdür. Antimikrobiyal, antidiyabetik, antiviral, antifungal, antiinflamatuar, antitüberküloz ve antitümör gibi birçok önemli aktiviteye sahiptir. Bu çalışmanın amacı, kalkonlar ve antimikrobiyal etkileri üzerine ilk kez bir bibliyometrik analiz yapmaktır. Bu çalışma, bu konudaki akademik literatürdeki eğilimleri ve temel bulguları ortaya koymayı amaçlamaktadır. Gereç ve Yöntemler: Bu makale, Bibliometrik paketinden Biblioshiny uygulamasını, R programını ve VOSviewer aracını kullanarak kalkonların antimikrobiyal aktivitesinin ayrıntılı bir bibliyometrik analizini gerçekleştirmektedir. Scopus veri tabanında 2014-2024 yılları arasında yayınlanmış 571 ilgili makale tarandı. Sonuçlar: Hindistan en önemli ülke olup, onu Brezilya ve Çin takip etmektedir. Peng ve ark. (2015) tarafından PHYTOTHER RES'te yayınlanan "A Review: The Pharmacology of Isoliquiritigenin" adlı makale, 222 atıf ile en çok katkıda bulunan çalışma olmuştur. 23 makale ile JOURNAL OF MOLECULAR STRUCTURE en önemli dergi, OSMANIA UNIVERSITY ise 77 makale ile en önemli kurumdur. Sonuç: İlgili zaman dilimi içinde kalkonlar ve antimikrobiyaller üzerine 571 İngilizce yayın tespit edildi. Sonuçlar şu şekildeydi: Makalelerin ortalama yaşı 5,18 yıldı ve belge başına ortalama 13,93 atıf vardı. 2.447 yazardan 13'ü tek yazardı. Uluslararası ortak yazarlık, tüm ortak yazarlı makalelerin %18,74'ünü oluşturuyordu. Üç alanlı grafiğe göre, en üst ülke "Brezilya", önde gelen yazar parametresi "Bandeira Pn." ve anahtar kelime "antimikrobiyal aktivite"dir

Anahtar Kelimeler

• Kalkonlar
• Antimikrobiyal
• Bibliyometrik Analiz
• Biblioshiny
• VOSviewer

A Bibliometric Analysis of Chalcones with Antimicrobial Potential

Öz

ABSTRACT: Purpose: Chalcones are secondary metabolites that occur naturally in plants and cannot be synthesized in the human and animal body. Its structure is 1,3-diaryl-2-propen-1-one and is the precursor of flavonoids. It has many important activities such as antimicrobial, antidiabetic, antiviral, antifungal, anti-inflammatory, antituberculosis and antitumor. The aim of this study was to conduct first time a bibliometric analysis on chalcones and their antimicrobial effects. It aims to reveal the trends and main findings in the academic literature on this subject. Material and Methods: This article performs a detailed bibliometric analysis of the antimicrobial activity of chalcones using the Biblioshiny application from the Bibliometric package with the R program and the VOSviewer tool. The Scopus database was searched for 571 relevant articles published between 2014 and 2024. Results: India is the most important country, followed by Brazil and then China. The article “A Review: The Pharmacology of Isoliquiritigenin” by Peng et al. (2015) published in PHYTOTHER RES was the most contributing study with 222 citations. With 23 articles, JOURNAL OF MOLECULAR STRUCTURE is the most important journal and OSMANIA UNIVERSITY is the most important institution with 77 articles. Conclusion: 571 English-language publications on chalcones and antimicrobials were identified within the relevant time frame. The results were as follows: the average age of the articles was 5.18 years, and there were an average of 13.93 citations per document. Of the 2,447 authors, 13 were sole authors. International co-authorship accounted for 18.74% of all co-authored articles. According to the three-field graph, the top country is “Brazil,” the leading author parameter is “Bandeira Pn.,” and the keyword is “antimicrobial activity.”

Anahtar Kelimeler

• Chalcones
• Antimicrobial
• Bibliometric Analysis
• Biblioshiny
• VOSviewer

Kaynakça

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