Biyolojik Silah Olarak Toksinler

Öz

Ölümcül olan kolayca ve düşük maliyet ile büyük miktarlarda üretilebilen, aerosol formda stabil olan, kolaycageniş alanlara yayılabilen ve insandan insana bulaşan etkenler ideal biyolojik silah ajanıdırlar. Botulinum,stafilokokkal enterotoksin B, ricin ve trikotesen mikotoksin gibi biyolojik toksinler, insandan insana bulaşma özelliğidışında tüm bu özelliklere sahiptirler. Bu derlemede, biyolojik silah olarak kullanılması muhtemel toksinler biyolojiközellikleri, biyolojik silah potansiyeleri, oluşturdukları klinik belirtiler, tanı, korunma ve tedavileri açısından gözdengeçirilmiştir

Anahtar Kelimeler

• Toksin, biyolojik silah, botulinum, stafilokokkal enterotoksin B, risin, trikotesen mikotoksin (T-2), sa k s i t o k s i n

Toxins As Agents Of Biological Weapons

Abstract

Agents that are lethal, easy and inexpensive to produce in large quantities, stable in aerosol for/with the abilityto be dispersed over wide areas, communicable from person to person are the ideal biologic warfare agent. Withthe exception of communicable from human to human, the biologic toxins such as Botulinum, staphylococcalenterotoxin B, ricin, and trichothecene mycotoxins possess all the properties mentioned. In this review, severalpotential biological warfare toxins in regard to their biology, potential for weaponization, and the clinical features,diagnosis, prevention, and treatment of the diseases that they cause have been reviewed

Keywords

• Toxin, biowarfare agents, botulinum, staphylococcal enterotoxin B, ricin, trichothecene mycotoxin (T-2), sa x i t o x i n

Kaynakça

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