The Role of Telomeres in Aging and Cancer Relationships

Öz

Telomeres have a major role in aging and cancer relationships. In cancer treatment and diagnosis, in addition to the traditional methods, the measurement of telomerase activity would be used as specific markers. The studies conducted on telomerase enzymes showed that they would be used effectively in the treatment of cancer. The role of telomeres in aging has also been the focus of many researches. It has been confirmed that telomere shortening plays universal role in shortening of the life of the human cells. Recent applications in the usage of teleomeres as a retardant in aging and also in cancer treatment are happened to be a promising development in this area.

Anahtar Kelimeler

• Telomere, aging, cancer

TELOMERLERİN YAŞLANMA VE KANSER İLİŞKİSİNDEKİ ROLÜ

Öz

Telomerlerin yaşlanma ve kanser ilişkisindeki rolü oldukça önemlidir. Kanser tedavisinde ve teşhisinde geleneksel yöntemlerin yanı sıra telomeraz aktivitesinin ölçümü özgün bir belirteç olarak kullanılabilir. Telomeraz enzimleri ile ilgili yapılmış olan çalışmalar kanser tedavisinde etkili bir şekilde kullanılabileceklerini göstermektedir. Ayrıca telomerlerin yaşlanma üzerindeki rolleri de birçok araştırmanın odak noktası olmuştur. Telomer kısalmasının insan hücresinin ömür uzunluğunun kısalmasında evrensel bir rol oynadığı yapılan çalışmalarla doğrulanmıştır. Telomerlerin, kanser tedavisinde ve yaşlanmayı geciktirici olarak kullanıma geçmiş olması umut verici bir gelişme olmuştur.

Anahtar Kelimeler

• Telomer, yaşlanma, kanser

Kaynakça

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