Vestibüler Uyarılmış Miyojenik Potansiyeller: Klinik Kullanımı

Yıl 2021, Cilt: 4 Sayı: 2, 51 - 58, 04.09.2021

Hatice Kavruk Ayşenur Aykul Burak Öztürk

Öz

Vestibüler uyarılmış miyojenik potansiyeller (VEMP), yüksek şiddette uyarana cevaben boyun (cVEMP) ya da göz kasları (oVEMP) üzerine yerleştirilen elektrotlarla kaydedilen kısa latanslı miyojenik cevaplardır. Yaygın vestibüler sistem hastalıklarının yanı sıra denge bozukluklarına yol açan çeşitli santral patolojilerde de anormal VEMP bulguları bildirilmiştir. VEMP testinin birçok vestibüler ve santral bozukluğun tanısında kullanımının faydalı olduğu düşünülmektedir. Bu derlemede ilgili literatür gözden geçirilerek çeşitli hastalıkların ayırt edici tanılamasında VEMP testinin klinik kullanımı ortaya konulmuştur.

Anahtar Kelimeler

VEMP, cVEMP, oVEMP, vestibüler sistem, santral bozukluklar

Kaynakça

• Akkuzu, G., Akkuzu, B., Ozluoglu, L. N. (2006). Vestibular evoked myogenic potentials in benign paroxysmal positional vertigo and Meniere's disease. European archives of oto-rhino-laryngology, 263(6): 510–517.   Allena, M., Magis, D., De Pasqua, V, Schoenen, J. (2007). The vestibulo- collic reflex is abnormal in migraine. Cephalalgia, 27: 1150–1155.
• Alpini, D., Pugnetti, L., Caputo, D., Cornelio, F., Capobianco, S., Cesarani, A. (2004). Vestibular evoked myogenic potentials in multiple sclerosis: clinical and imaging correlations, Mult Scler, 10(3): 316–321.
• Amali, A., Mahdi, P., Yazdi, A. K., Ashtiyani, M. T. K., Yazdani, N., Vakili, V., Pourbakht, A. (2014). Saccular function in otosclerosis patients: Bone conducted-vestibular evoked myogenic potential analysis. Acta Medica Iranica, 52(2): 111–115.
• Angeli, S. I., Goncalves, S. (2019). Cervical VEMP tuning changes by Meniere’s disease stages. Laryngoscope Investigative Otolaryngology, 4(5): 543–549.
• Angunsri N., Omi E., Itasaka Y., Ishikawa K. (2010). Vestibular evoked myogenic potential in acoustic neuroma. Otol Jpn, 20(5): 735-742.
• Baier, B., Stieber, N., Dieterich, M. (2009). Vestibular-evoked myogenic potentials in vestibular migraine. J Neurol, 256(9): 1447-14454.
• Bi, W. L., Brewster, R., Poe, D., Vernick, D., Lee, D. J., Corrales, C. E., Dunn, I. F. (2017). Superior semicircular canal dehiscence syndrome. J Neurosurg, 127(6): 1268-1276.
• Boldingh, M. I., Ljostad, U., Mygland, A., Monstad, P. (2011). Vestibular sensitivity in vestibular migraine: VEMPs and motion sickness susceptibility. Cephalalgia, 31(11): 1211-1219.
• Brantberg, K., Bergenius, J., Mendel, L., Witt, H., Tribukait, A., Ygge, J. (2001). Symptoms, findings and treatment in patients with dehiscence of the superior semicircular canal. Acta Otolaryngol, 121: 68–75.
• Brantberg, K., Bergenius, J., Tribukait, A. (1999). Vestibular-evoked myogenic potentials in patients with dehiscence of the superior semicircular canal. Acta Otolaryngol, 119: 633-640.
• Chen, L., Xu, H., Wang, W. Q., Zhang, Q. Q., Lv, Q. Y., Song, X. C. (2016). Evaluation of the otolith function using c/oVEMPs in patients with Ménière’s disease. Journal of Otolaryngology - Head and Neck Surgery, 45(1): 16–21.
• Crnošija, L., Krbot Skorić, M., Gabelić, T., Adamec, I., Habek, M. (2017). Vestibular evoked myogenic potentials and MRI in early multiple sclerosis: Validation of the VEMP score. Journal of the Neurological Sciences, 372: 28–32.
• Curthoys, I. S. (2010). A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli. Clinical Neurophysiology, 121(2): 132–144.
• Curthoys, I. S., Manzari, L., Smulders, Y. E., Burgess, A. M. (2009). A review of the scientific basis and practical application of a new test of utricular function - Ocular vestibular - Evoked myogenic potentials to bone-conducted vibration. Acta Otorhinolaryngologica Italica, 29(4): 179–186.
• Day, A. S., Wang, C. Te, Chen, C. N., Young, Y. H. (2008). Correlating the cochleovestibular deficits with tumor size of acoustic neuroma. Acta Oto-Laryngologica, 128(7): 756–760.
• de Natale, E. R., Ginatempo, F., Paulus, K. S., Manca, A., Mercante, B., Pes, G. M., Agnetti, V., Tolu, E., Deriu, F. (2015). Paired neurophysiological and clinical study of the brainstem at different stages of Parkinson’s Disease. Clinical Neurophysiology, 126(10): 1871–1878.
• Dlugaiczyk, J., Habs, M., Dieterich, M. (2020). Vestibular evoked myogenic potentials in vestibular migraine and Menière’s disease: cVEMPs make the difference. Journal of Neurology, 267(1): 169-180.
• Doaa, E., Kozou, H., Mekky, J., Ghanem, D. (2020). Assessment of cervical and ocular vestibular evoked myogenic potentials in migraine patients. The Egyptian Journal of Otolaryngology, 36(19).
• Eleftheriadou, A., Deftereos, S. N., Zarikas, V., Panagopoulos, G., Sfetsos, S., Karageorgiou, C. L., Ferekidou, E., Kandiloros, D., Korres, S. (2009). The diagnostic value of earlier and later components of Vestibular Evoked Myogenic Potentials (VEMP) in Multiple Sclerosis. Journal of Vestibular Research: Equilibrium and Orientation, 19(1–2): 59–66.
• El-Khousht, M.M., Hossni, N.A., El-abd, S.M., El-shenawy, A.M. (2010). Vestibular Evoked Myogenic Potentials (VEMP) in Conductive Hearing Loss, 78(1): 539–541.
• Eryaman, E., Oz, I. D., Ozker, B. Y., Erbek, S., Erbek, S. S. (2012). Evaluation of vestibular evoked myogenic potentials during benign paroxysmal positional vertigo attacks; neuroepithelial degeneration?. B-ENT, 8(4): 247–250. 
• Gabelić, T., Krbot Skorić, M., Adamec, I., Barun, B., Zadro, I., Habek, M. (2015). The vestibular evoked myogenic potentials (VEMP) score: A promising tool for evaluation of brainstem involvement in multiple sclerosis. European Journal of Neurology, 22(2): 261–269.
• Gabelić, T., Krbot, M., Sefer, A.B., Isgum, V., Adamec, I., Habek, M. (2013). Ocular and cervical vestibular evoked myogenic potentials in Multiple Sclerosis. Journal of Clinical Neurophysiology, 30(1): 86-91.
• Gazioglu, S., Boz, C. (2012). Ocular and cervical vestibular evoked myogenic potentials in multiple sclerosis patients. Clinical Neurophysiology, 123(9): 1872–1879.
• Godha, S., Upadhyay Mundra, A., Mundra, R. K., Bhalot, L., Singh, A. (2020). VEMP: An Objective Test for Diagnosing the Cases of BPPV. Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 72(2): 251–256.  
• Govender, S., Dennis, D. L., Colebatch, J. G. (2015). Vestibular evoked myogenic potentials (VEMPs) evoked by air- and bone-conducted stimuli in vestibular neuritis. Clinical Neurophysiology, 126(10): 2004–2013.
• Govender, S., Rosengren, S. M., Colebatch, J. G. (2011). Vestibular neuritis has selective effects on air- and bone-conducted cervical and ocular vestibular evoked myogenic potentials. Clinical Neurophysiology, 122(6): 1246–1255.
• Guo, P., Sun, W., Shi, S., zhang, F., Wang, J., Wang, W. (2019). Quantitative evaluation of endolymphatic hydrops with MRI through intravenous gadolinium administration and VEMP in unilateral definite Meniere’s disease. European Archives of Oto-Rhino-Laryngology, 276(4): 993–1000.