GENEL ANESTEZİ ALTINDA VİDEO YARDIMLI TORASİK CERRAHİ SIRASINDA GELİŞEN KOUNİS SENDROMU: BİR OLGU SUNUMU

Yıl 2025, Cilt: 4 Sayı: S2, 23 - 24, 29.12.2025

Ferdi Gülaştı

https://izlik.org/JA76FW66FF

Öz

Kounis Sendromu, alerjik bir reaksiyon ile mast hücreleri ve trombositlerin aktivasyonu sonucu ortaya çıkan, koroner arterlerde vazospazm veya trombüs oluşumu ile seyreden nadir bir akut koroner sendromdur (1,2). Klinik bulgular arasında hipotansiyon, aritmiler, artmış havayolu basıncı ve hatta kardiyak arrest yer alabilir (3,4). Perioperatif dönemde çoklu ilaç maruziyeti nedeniyle tanı koymak sıklıkla zordur ve bu durum mortalite riskini artırır (5). Bu olgu, genel anestezi altında gelişen ve rokuronyum ile sefazolinin olası tetikleyici ajanlar olarak değerlendirildiği bir Kounis Sendromu vakasına dikkat çekmeyi amaçlamaktadır.

Anahtar Kelimeler

Kounis Sendromu , Genel anestezi , Koroner vazospazm

DEVELOPMENT OF KOUNIS SYNDROME IN VIDEO-ASSISTED THORACIC SURGERY UNDER GENERAL ANESTHESIA: A CASE REPORT

https://izlik.org/JA76FW66FF

Öz

Kounis Syndrome is a rare acute coronary syndrome caused by mast cell and platelet activation following an allergic reaction, leading to coronary artery vasospasm or thrombus formation (1,2). Clinical manifestations may include hypotension, arrhythmias, increased airway pressure, and even cardiac arrest (3,4). Diagnosis in the perioperative period is often difficult due to exposure to multiple drugs, increasing mortality risk (5). This case highlights Kounis Syndrome that developed under general anesthesia, in which rocuronium and cefazolin were considered possible triggering agents.

Anahtar Kelimeler

Kounis Syndrome , General anesthesia , Coronary vasospasm

Kaynakça

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