A CASE OF PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA

Yıl 2015, Cilt: 7 Sayı: 1, 30 - 32, 22.03.2015

Aydan Kılıçarslan

Öz

Primary cutaneous anaplastic large cell lymphoma is a skin lymphoma which is characterized by atypical T lymphocytes. Ulceration is commonly seen over the lesions. Multiple lesions are rare and presentation as a solitary lesion is common. It’s important to differentiate this variant from other the lymphoma of the skin in terms of determine treatment plan and prognosis. Herein we would like to report a case which is an example of primary cutaneous anaplastic large cell lymphoma and briefly review the literature.

Anahtar Kelimeler

A CASE OF PRIMARY CUTANEOUS ANAPLASTIC LARGE CELL LYMPHOMA

PRIMER KUTANÖZ ANAPLASTİK BÜYÜK HÜCRELİ LENFOMA OLGUSU

Öz

Primer kutanöz anaplastik büyük hücreli lenfoma, derinin atipik, iri T lenfositlerle ka-rakterize lenfomasıdır. Lezyonların yüzeyi sıklıkla ülseredir. Genellikle tek ve soliter olmakla birlikte nadiren multipl de olabilir. Derinin lenfomalarından ayrıcı tanısının yapılması; tedavi planı ve prognozu belirlemek açısından önemlidir. Bu yazıda Primer Kutanöz Anaplastik Büyük Hücreli Lenfomaya (PKABHL) örnek bir olguyu literatürle paylaşmak istedik.

Anahtar Kelimeler

Primer kutanöz anaplastik büyük hücreli lenfoma, CD30+ lenfoma, kemoterapi

Kaynakça

• 1. Willemze R, Kerl H, Sterry W, et al. EORTC classification for primary cutaneous lymphomas; a proposal from the cuteneous lymphoma study group of the European Organisation for the Research and Treatment of Cancer. Blood. 1997;90:354.
• 2. ERTAM, İlgen, et al. "Multifokal Primer Kutanöz Anaplastik Büyük Hücreli Lenfoma Olgusu." Türkiye Klinikleri Dermatoloji Dergisi 2008;18: 110-113.
• 3. Willemze R, Jaffe ES, Burg G, Cer-roni L, Berti E, Swerdlow SH, et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005;105:3768–85.
• 4. Kaudewitz P, Burg G, Stein H. Ki-1 (CD30) positive cutaneous anaplastic large cell lymphomas. Curr Probl Dermatol. 1990;19:150–6.
• 5. Miyagaki T, Sugaya M, Miyamato A, et al. A case of primary cutaneous anaplastic large cell lymphoma with prominent epidermotropism. Int J Hematol . 2012;95:711-715.
• 6. Paulli M, Berti E, Rosso R, et al. CD30/Ki-1-positive lymphoproliferative disorders of the skin- clinico-pathologic correlation and statistical analysis of 86 cases: a multicentric study from the European Organiza- tion for Research and Treatment of Cancer Cutaneous Lymphoma Project Group. J Clin Oncol. 1995;13:1343.
• 7. Stein H, Foss HD, Dürkop H, Mara-fioti T, Delsol FG, et al.CD30+ ana-plastik large cell lymphoma : a review of its histopathologic, genetic, and clinical features. Blood.2000; 96: 3681-3695.
• 8. Stein H, Dallenbach F. Diffuse large cell lymphomas of B and T cell type. In: Knowles DM, ed.Neoplastic He-matopathology. Baltimore, Md: Williams & Wilkins; 1992:554.