IMPACT OF T WAVE AMPLITUDE IN LEAD aVR ON PREDICTING APPROPRIATE THERAPIES IN HYPERTROPHIC CARDIOMYOPATHY PATIENTS WITH AN IMPLANTABLE CARDIOVERTER DEFIBRILLATOR

Yıl 2018, Cilt: 5 Sayı: 1, 5 - 8, 25.02.2018

Begüm Söyleyici Pelinsu Elif Hünkar Çağrı Girit Cansu Kurt Fatih Mehmet Uçar

Öz

Aims: Although implantable cardioverter defibrillator reduces mortality in hypertrophic cardiomyopathy patients,
inappropriate implantable cardioverter defibrillator shocks are related to increased mortality. The aim of this study
is to investigate whether a new electrocardiographic marker of T wave amplitude in lead aVR can be used to predict
appropriate therapy of implantable cardioverter defibrillator (shock or anti-tachycardia pacing) in hypertrophic cardiomyopathy
patients.

Methods: Thirty-six hypertrophic cardiomyopathy patients, who were admitted to the outpatient clinic for pacemaker
control, with implantable cardioverter defibrillator were retrospectively examined (mean age: 51 ± 10.2 years,
72.2% male). The primary endpoint was appropriate implantable cardioverter defibrillator therapy. All hematological,
biochemical and electrocardiogram parameters were measured before implantable cardioverter defibrillator was
implanted.

Results: Over a median follow-up period of 33 months, 9 (25%) patients experienced appropriate implantable
cardioverter defibrillator therapy. Heart rate and QRS interval were similar between groups. QT and QTc values
were higher in patients that received appropriate shocks. Patients who have T wave inversion were higher in therapy
positive group. T wave amplitude in lead aVR values were significantly associated with appropriate therapy.

Conclusion: Using simple ECG parameters, we may predict arrhythmic episodes before ICD implantation and an
improvement of the medical antiarrhythmic therapy might be protective for HCM patients with ICD.

Anahtar Kelimeler

Hypertrophic, cardiomyopathy, defibrillator, electrocardiography

Kaynakça

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