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THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS

Yıl 2018, Cilt: 5 Sayı: 2, 37 - 42, 01.06.2018

Öz

Aims: To perform a comparative analysis of individual clinical and laboratory indicators in the differential diagnosis of conditionally limited and generalized forms of postpartum septic complications.

Methods: The study included 34 patients at Gynecology Department of the Zaporizhzhia Regional Clinical Hospital from 2013 to 2016 with postpartum purulent-septic diseases. Patients were divided into 2 groups. Group I consisted of 15 women who were diagnosed with a conditionally limited postpartum purulent-inflammatory disease (endometritis). Group II included 19 women with generalized forms of postpartum purulent-inflammatory diseases (peritonitis, sepsis). For the diagnosis of Multiple Organ Failure due to sepsis, we used the Sequential (Sepsis-Related) Organ Failure Assessment and quick Sequential (Sepsis-Related) Organ Failure Assessment. The differences between the first and second group were assessed by using the Mann-Whitney U test and STATISTICA Version 10.

Results: Body temperature was increased in all 34 patients. The average heart rate in group I was 91.6 ± 8.35 beats/ min and 102.26 ± 16.42 beats/min in group II. The average respiratory rate was 19.07 ± 2.49 breaths/min in group I and 24.16 ± 5.09 breaths/min in group II. In group I, none of the patients scored a total of two or more points on the Sequential (Sepsis-Related) Organ Failure Assessment and quick Sequential (Sepsis-Related) Organ Failure Assessment scales; in group II, there were 5 (26.32%) patients who had scored two points or more on the Sequential (Sepsis-Related) Organ Failure Assessment scale; and 2 (10.53%) patients had scored 2 points or more in the quick Sequential (Sepsis-Related) Organ Failure Assessment scale.

Conclusion: Clinical cases of postpartum period with inflammation of uterus and signs of multiple organ failure should be; regarded as a septic state, assessed by the Sequential (Sepsis-Related) Organ Failure Assessment scale as they require urgent medical help.

Kaynakça

  • 1. World Health Organization, UNICEF, United Nations Population Fund and The World Bank. Trends in maternal mortality: 1990 to 2015. WHO, Geneva, 2015.
  • 2. Lapinsky SE. Obstetric infections. Crit Care Clin 2013;29(3):509-20.
  • 3. Slynko OM, Pavliuchenko МІ, Mikhisor ІP et al. Modern tactics of observation the postpartum purulent-septic complications. Zaporozhye Medical Journal 2014;2(83):69-71.
  • 4. Central Intelligence Agency. Field listing: maternal mortality ratio. The world Factbook. Available from URL: https://www.cia.gov/library/publications/the-world-factbook/fields/2223.html.
  • 5. Jawad I, Lukšić I, Rafnsson SB. Assessing available information on the burden of sepsis: global estimates of incidence, prevalence and mortality. J Glob Health 2012;2(1):010404.
  • 6. Netto CM, Whitten M, Shetty N. Postpartum sepsis. Br J Hosp Med 2015;76(8):118-21.
  • 7. On approval of clinical protocols for obstetric and gynecological care. Order of the Ministry of Health of Ukraine: 2004 Dec. Report No: 676.
  • 8. Cataldo R, Vennari M, Agro FE. Septic and septic shock. In: Agro FE, editor. Body Fluid Management From Physiology To Therapy. Springer; 2013.p.137-48.
  • 9. Parson M. Cytokine storm in the pediatric oncology patient, differential diagnoses and workup. Journal of Peddanana 2010;27(5):253-8.
  • 10. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Critical Care Medicine 1992;20(6):864–74.
  • 11. Knowles SJ, O’Sullivan NP, Meenan AM et al. Maternal sepsis incidence, etiology and outcome for mother and fetus: a prospective study. BJOG 2015;122(5):663-71.
  • 12. Singer M, Deutschman CS, Seymour CW. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016;315(8):801-10.
  • 13. Dombrovskiy VY, Martin AA, Sunderram J et al. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med 2007;35:1244–50.
  • 14. Torio CM, Moore BJ. National inpatient hospital costs: the most expensive conditions by payer, 2013. Rockville (MD) Healthcare Cost and Utilization Project (US). Agency for Healthcare Research and Quality: 2016 May. Statistical Brief: 204.
  • 15. Zimmerman JE, Kramer AA, McNair DS et al. Acute physiology and chronic health evaluation (APACHE) IV: hospital mortality assessment for today’s critically ill patients. Critical Care Medicine 2006;34(5):1297–310.
  • 16. Jones AE, Trzeciak S, Kline JA. The sequential organ failure assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation. Crit Care Med 2009;37(5):1649–54.
  • 17. Ceriani R, Mazzoni M, Bortone F et al. Application of the sequential organ failure assessment score to cardiac-surgical patients. Chest 2003;123(4):1229-39.
  • 18. Harrison A, Yadav H, Pickering BW et al. Validation of computerized automatic calculation of the sequential organ failure assessment score. Critical Care Research and Practice 2013;2013:975672.
Yıl 2018, Cilt: 5 Sayı: 2, 37 - 42, 01.06.2018

Öz

Kaynakça

  • 1. World Health Organization, UNICEF, United Nations Population Fund and The World Bank. Trends in maternal mortality: 1990 to 2015. WHO, Geneva, 2015.
  • 2. Lapinsky SE. Obstetric infections. Crit Care Clin 2013;29(3):509-20.
  • 3. Slynko OM, Pavliuchenko МІ, Mikhisor ІP et al. Modern tactics of observation the postpartum purulent-septic complications. Zaporozhye Medical Journal 2014;2(83):69-71.
  • 4. Central Intelligence Agency. Field listing: maternal mortality ratio. The world Factbook. Available from URL: https://www.cia.gov/library/publications/the-world-factbook/fields/2223.html.
  • 5. Jawad I, Lukšić I, Rafnsson SB. Assessing available information on the burden of sepsis: global estimates of incidence, prevalence and mortality. J Glob Health 2012;2(1):010404.
  • 6. Netto CM, Whitten M, Shetty N. Postpartum sepsis. Br J Hosp Med 2015;76(8):118-21.
  • 7. On approval of clinical protocols for obstetric and gynecological care. Order of the Ministry of Health of Ukraine: 2004 Dec. Report No: 676.
  • 8. Cataldo R, Vennari M, Agro FE. Septic and septic shock. In: Agro FE, editor. Body Fluid Management From Physiology To Therapy. Springer; 2013.p.137-48.
  • 9. Parson M. Cytokine storm in the pediatric oncology patient, differential diagnoses and workup. Journal of Peddanana 2010;27(5):253-8.
  • 10. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Critical Care Medicine 1992;20(6):864–74.
  • 11. Knowles SJ, O’Sullivan NP, Meenan AM et al. Maternal sepsis incidence, etiology and outcome for mother and fetus: a prospective study. BJOG 2015;122(5):663-71.
  • 12. Singer M, Deutschman CS, Seymour CW. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016;315(8):801-10.
  • 13. Dombrovskiy VY, Martin AA, Sunderram J et al. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med 2007;35:1244–50.
  • 14. Torio CM, Moore BJ. National inpatient hospital costs: the most expensive conditions by payer, 2013. Rockville (MD) Healthcare Cost and Utilization Project (US). Agency for Healthcare Research and Quality: 2016 May. Statistical Brief: 204.
  • 15. Zimmerman JE, Kramer AA, McNair DS et al. Acute physiology and chronic health evaluation (APACHE) IV: hospital mortality assessment for today’s critically ill patients. Critical Care Medicine 2006;34(5):1297–310.
  • 16. Jones AE, Trzeciak S, Kline JA. The sequential organ failure assessment score for predicting outcome in patients with severe sepsis and evidence of hypoperfusion at the time of emergency department presentation. Crit Care Med 2009;37(5):1649–54.
  • 17. Ceriani R, Mazzoni M, Bortone F et al. Application of the sequential organ failure assessment score to cardiac-surgical patients. Chest 2003;123(4):1229-39.
  • 18. Harrison A, Yadav H, Pickering BW et al. Validation of computerized automatic calculation of the sequential organ failure assessment score. Critical Care Research and Practice 2013;2013:975672.
Toplam 18 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

Varahabhatla Vamsi Bu kişi benim

Vinisha Tekwani Bu kişi benim

Pavliuchenko Myhaelo Ivanovich Bu kişi benim

Yayımlanma Tarihi 1 Haziran 2018
Gönderilme Tarihi 3 Mayıs 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 5 Sayı: 2

Kaynak Göster

APA Vamsi, V., Tekwani, V., & Ivanovich, P. M. (2018). THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS. Turkish Medical Student Journal, 5(2), 37-42.
AMA Vamsi V, Tekwani V, Ivanovich PM. THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS. TMSJ. Haziran 2018;5(2):37-42.
Chicago Vamsi, Varahabhatla, Vinisha Tekwani, ve Pavliuchenko Myhaelo Ivanovich. “THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS”. Turkish Medical Student Journal 5, sy. 2 (Haziran 2018): 37-42.
EndNote Vamsi V, Tekwani V, Ivanovich PM (01 Haziran 2018) THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS. Turkish Medical Student Journal 5 2 37–42.
IEEE V. Vamsi, V. Tekwani, ve P. M. Ivanovich, “THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS”, TMSJ, c. 5, sy. 2, ss. 37–42, 2018.
ISNAD Vamsi, Varahabhatla vd. “THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS”. Turkish Medical Student Journal 5/2 (Haziran 2018), 37-42.
JAMA Vamsi V, Tekwani V, Ivanovich PM. THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS. TMSJ. 2018;5:37–42.
MLA Vamsi, Varahabhatla vd. “THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS”. Turkish Medical Student Journal, c. 5, sy. 2, 2018, ss. 37-42.
Vancouver Vamsi V, Tekwani V, Ivanovich PM. THE IMPORTANCE OF INDIVIDUAL CLINICAL AND LABORATORY INDICATORS IN THE DIFFERENTIAL DIAGNOSIS OF POSTPARTUM SEPTIC COMPLICATIONS. TMSJ. 2018;5(2):37-42.