Olgu Sunumu
BibTex RIS Kaynak Göster
Yıl 2020, Cilt: 7 Sayı: 1, 26 - 33, 29.02.2020

Öz

Kaynakça

  • 1. Pileri SA, Ascani S, Cox MS et al. Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia 2007;21(2):340-50. 2. Claerhout H, Sophie Van Aelst S, Melis C et al. Clinicopathological characteristics of de novo and secondary myeloid sarcoma: a monocentric retrospective study. Eur J Haematol 2018;100(6):603-12. 3. Wilson CS, Medeiros LJ. Extramedullary manifestations of myeloid neoplasms. Am J Clin Pathol 2015;144(2):219-39. 4. Almond LM, Charalampakis M, Ford SJ et al. Myeloid sarcoma: presentation, diagnosis, and treatment. Clin Lymphoma, Myeloma Leuk 2017;17(5):263-7. 5. Békássy AN, J Hermans J, Gorin NC et al. Granulocytic sarcoma after allogeneic bone marrow transplantation: a retrospective European multicenter survey. Acute and Chronic Leukemia Working Parties of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 1996;17(5):801-8. 6. Stolzel F, Rollig C, Radke J et al. F-FDG-PET/CT for detection of extramedullary acute myeloid leukemia. Haematologica 2011;96(10):1552-6. 7. Campidelli C, Agostinelli C, Stitson R et al. Myeloid sarcoma: extramedullary manifestation of myeloid disorders. Am J Clin Pathol 2009;132(3):426-37. 8. Magdy M, Abdel Karim N, Eldessouki I et al. Myeloid sarcoma. Oncol Res Treat 2019;42(4):219-24. 9. Kaygusuz G, Kankaya D, Ekinci C et al. Myeloid sarcomas: a clinicopathologic study of 20 cases. Turk J Haematol 2015;32(1):35-42. 10. Yamauchi K, Yasuda M. Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer 2002;94(6):1739-46. 11. Movassaghian M, Brunner AM, Blonquist TM et al. Presentation and outcomes among patients with isolated myeloid sarcoma: a Surveillance, Epidemiology, and End Results database analysis. Leuk Lymphoma 2015;56(6):1698-703. 12. Kawamoto K, Miyoshi H, Yoshida N et al. Clinicopathological, cytogenetic, and prognostic analysis of 131 myeloid sarcoma patients. Am J Surg Pathol 2016;40(11):1473-83.

CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE

Yıl 2020, Cilt: 7 Sayı: 1, 26 - 33, 29.02.2020

Öz

Aims: This retrospective study aims to emphasize clinicopathological data and diagnosis of an uncommon myeloid neoplasm;
myeloid sarcoma. Methods: Data of all patients from 2000-2019 were retrieved from the archives of Trakya University School
of Medicine Hematology and Pathology Departments. Patients’ charts were examined retrospectively by collecting data including age, gender, anatomic site, history of hematological malignancy, blood count, pathological characteristics and treatments
administered. Results: There were 8 patients; 6 male and 2 female. The median age was 42.5 years (range: 29-69 years). The
most prevalently involved sites were skin, lymph node and bone/soft tissue. There were six patients as myeloid sarcoma with
preexisting or concurrent acute myeloid leukemia, one patient as de novo and one patient as acute myeloid leukemia with myelodysplasia related changes. One of the concurrent acute myeloid leukemia patients was Down syndrome related acute myeloid
leukemia with myeloid sarcoma. Immunohistochemically, out of 8 patients, 4 were of myelomonocytic, 2 were of the myelocytic
and 2 were of the monocytic differentiation. Conclusion: Myeloid sarcoma is a tumor mass made up of immature myeloid blasts
appearing at an anatomical site other than bone marrow. Taking into account of having a challenging diagnosis, unusual cellular
infiltration at any site on a patient especially with a history of acute myeloid leukemia should have myeloid sarcoma in their
differential diagnosis. Keywords: Myeloid sarcoma, acute myeloid leukemia, myeloid neoplasia

Kaynakça

  • 1. Pileri SA, Ascani S, Cox MS et al. Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients. Leukemia 2007;21(2):340-50. 2. Claerhout H, Sophie Van Aelst S, Melis C et al. Clinicopathological characteristics of de novo and secondary myeloid sarcoma: a monocentric retrospective study. Eur J Haematol 2018;100(6):603-12. 3. Wilson CS, Medeiros LJ. Extramedullary manifestations of myeloid neoplasms. Am J Clin Pathol 2015;144(2):219-39. 4. Almond LM, Charalampakis M, Ford SJ et al. Myeloid sarcoma: presentation, diagnosis, and treatment. Clin Lymphoma, Myeloma Leuk 2017;17(5):263-7. 5. Békássy AN, J Hermans J, Gorin NC et al. Granulocytic sarcoma after allogeneic bone marrow transplantation: a retrospective European multicenter survey. Acute and Chronic Leukemia Working Parties of the European Group for Blood and Marrow Transplantation. Bone Marrow Transplant 1996;17(5):801-8. 6. Stolzel F, Rollig C, Radke J et al. F-FDG-PET/CT for detection of extramedullary acute myeloid leukemia. Haematologica 2011;96(10):1552-6. 7. Campidelli C, Agostinelli C, Stitson R et al. Myeloid sarcoma: extramedullary manifestation of myeloid disorders. Am J Clin Pathol 2009;132(3):426-37. 8. Magdy M, Abdel Karim N, Eldessouki I et al. Myeloid sarcoma. Oncol Res Treat 2019;42(4):219-24. 9. Kaygusuz G, Kankaya D, Ekinci C et al. Myeloid sarcomas: a clinicopathologic study of 20 cases. Turk J Haematol 2015;32(1):35-42. 10. Yamauchi K, Yasuda M. Comparison in treatments of nonleukemic granulocytic sarcoma: report of two cases and a review of 72 cases in the literature. Cancer 2002;94(6):1739-46. 11. Movassaghian M, Brunner AM, Blonquist TM et al. Presentation and outcomes among patients with isolated myeloid sarcoma: a Surveillance, Epidemiology, and End Results database analysis. Leuk Lymphoma 2015;56(6):1698-703. 12. Kawamoto K, Miyoshi H, Yoshida N et al. Clinicopathological, cytogenetic, and prognostic analysis of 131 myeloid sarcoma patients. Am J Surg Pathol 2016;40(11):1473-83.
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri
Bölüm Olgu Sunumu
Yazarlar

Fatih Erkan Akay Bu kişi benim 0000-0001-7598-1016

Hakkı Onur Kırkızlar Bu kişi benim 0000-0001-7523-8599

Elif Mercan Bu kişi benim

Fulya Öz Puyan Bu kişi benim

Yayımlanma Tarihi 29 Şubat 2020
Gönderilme Tarihi 9 Şubat 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 7 Sayı: 1

Kaynak Göster

APA Akay, F. E., Kırkızlar, H. O., Mercan, E., Öz Puyan, F. (2020). CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE. Turkish Medical Student Journal, 7(1), 26-33.
AMA Akay FE, Kırkızlar HO, Mercan E, Öz Puyan F. CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE. TMSJ. Şubat 2020;7(1):26-33.
Chicago Akay, Fatih Erkan, Hakkı Onur Kırkızlar, Elif Mercan, ve Fulya Öz Puyan. “CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE”. Turkish Medical Student Journal 7, sy. 1 (Şubat 2020): 26-33.
EndNote Akay FE, Kırkızlar HO, Mercan E, Öz Puyan F (01 Şubat 2020) CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE. Turkish Medical Student Journal 7 1 26–33.
IEEE F. E. Akay, H. O. Kırkızlar, E. Mercan, ve F. Öz Puyan, “CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE”, TMSJ, c. 7, sy. 1, ss. 26–33, 2020.
ISNAD Akay, Fatih Erkan vd. “CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE”. Turkish Medical Student Journal 7/1 (Şubat 2020), 26-33.
JAMA Akay FE, Kırkızlar HO, Mercan E, Öz Puyan F. CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE. TMSJ. 2020;7:26–33.
MLA Akay, Fatih Erkan vd. “CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE”. Turkish Medical Student Journal, c. 7, sy. 1, 2020, ss. 26-33.
Vancouver Akay FE, Kırkızlar HO, Mercan E, Öz Puyan F. CLINICOPATHOLOGICAL FEATURES OF MYELOID SARCOMA PATIENTS FROM A SINGLE CENTER EXPERIENCE. TMSJ. 2020;7(1):26-33.