Journal of Turgut Ozal Medical Center

Cilt: 22 Sayı: 2 11 Aralık 2015
  • Öztun Temelli
  • Cemal Ekici
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Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature

Öz

Pleomorphic adenoma is the most common benign salivary gland neoplasm (%75-80). It is found mostly in the parotid gland in middle-aged women. The optimal treatment is superficial or total parotidectomy with facial nerve preservation, which results in local control rates of 95% or higher. Radiotherapy (RT) is indicated for ositive margins, unresectable tumours, and multifocal recurrences after prior resection. Local control rates after RT for microscopic and gross residual tumour are approximately 80% to 85% and 40% to 60%, respectively. In this article, we share our experience of 2 cases of recurrent pleomorphic adenoma.

Key Words: Pleomorphic Adenoma; Radiotherapy; Treatment.

Anahtar Kelimeler

Kaynakça

  1. Mendenhall WM, Mendenhall CM, Werning JW, Malyapa RS, Mendenhall NP. Salivary gland pleomorphic adenoma. Am J Clin Oncol 2008;31(1):95-9.
  2. Laccourreye H, Laccourreye O, Cauchois R, et al. Total conservative parotidectomy for primary benign pleomorphic adenoma of the parotid gland: a 25-year experience with 229 patients. Laryngoscope 1994;104:1487-94.
  3. Satar B, Gerek M, Yetişer S, Akkaya A, Özkaptan Y. Major Tükrük Bezi Tümörleri: 93 Olgunun Analizi. Turkiye Klinikleri J E.N.T 2001;1(3):123-8.
  4. Ohtake S, Cheng J, Ida H, et al. Precancerous foci in pleomorphic adenoma of the salivary gland: recognition of focal carcinoma and atypical tumor cells by P53 immunohistochemistry. J Oral Pathol Med 2002;31:590-7.
  5. Nouraei SA, Ferguson MS, Clarke PM, et al. Metastasizing pleomorphic salivary adenoma. Arch Otolaryngol Head Neck Surg 2006;132:788-93.
  6. Alves FA, Perez DE, Almeida OP, et al. Pleomorphic adenoma of the submandibula gland: clinicopathological and immunohistochemical features of 60 cases in Brazil. Arch Otolaryngol Head Neck Surg 2002;128:1400-03.
  7. Hamada T, Matsukita S, Goto M,et al. Mucin expression in pleomorphic adenoma of salivary gland: a potential role for MUC1 as a marker to predict recurrence. J Clin Pathol 2004;57:813-21.
  8. Wallace AS, Morris CG, Kirwan JM, Werning JW, Mendenhall WM. Radiotherapy for pleomorphic adenoma. Am J Otolaryngol 2013;34(1):36-40.

Ayrıntılar

Birincil Dil

Tr

Konular

-

Bölüm

-

Yazarlar

Öztun Temelli Bu kişi benim

Cemal Ekici Bu kişi benim

Yayımlanma Tarihi

11 Aralık 2015

Gönderilme Tarihi

11 Aralık 2015

Kabul Tarihi

-

Yayımlandığı Sayı

Yıl 2015 Cilt: 22 Sayı: 2

Kaynak Göster

APA
Temelli, Ö., & Ekici, C. (2015). Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature. Journal of Turgut Ozal Medical Center, 22(2), 125-127. https://izlik.org/JA48AW84ZB
AMA
1.Temelli Ö, Ekici C. Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature. J Turgut Ozal Med Cent. 2015;22(2):125-127. https://izlik.org/JA48AW84ZB
Chicago
Temelli, Öztun, ve Cemal Ekici. 2015. “Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature”. Journal of Turgut Ozal Medical Center 22 (2): 125-27. https://izlik.org/JA48AW84ZB.
EndNote
Temelli Ö, Ekici C (01 Aralık 2015) Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature. Journal of Turgut Ozal Medical Center 22 2 125–127.
IEEE
[1]Ö. Temelli ve C. Ekici, “Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature”, J Turgut Ozal Med Cent, c. 22, sy 2, ss. 125–127, Ara. 2015, [çevrimiçi]. Erişim adresi: https://izlik.org/JA48AW84ZB
ISNAD
Temelli, Öztun - Ekici, Cemal. “Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature”. Journal of Turgut Ozal Medical Center 22/2 (01 Aralık 2015): 125-127. https://izlik.org/JA48AW84ZB.
JAMA
1.Temelli Ö, Ekici C. Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature. J Turgut Ozal Med Cent. 2015;22:125–127.
MLA
Temelli, Öztun, ve Cemal Ekici. “Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature”. Journal of Turgut Ozal Medical Center, c. 22, sy 2, Aralık 2015, ss. 125-7, https://izlik.org/JA48AW84ZB.
Vancouver
1.Öztun Temelli, Cemal Ekici. Role of Radiotherapy in Parotid Pleomorphic Adenoma: Two Case Reports and a Review of the Literature. J Turgut Ozal Med Cent [Internet]. 01 Aralık 2015;22(2):125-7. Erişim adresi: https://izlik.org/JA48AW84ZB