BibTex RIS Kaynak Göster

Calculation of the Volume of Fourth Ventricle and the Length of Herniation Using the ImageJ Software in Patients with Chiari Type I malformation

Yıl 2012, Cilt: 19 Sayı: 4, 249 - 255, 01.08.2012

Öz

Objective: The Chiari type 1 malformation is a congenital anomaly which is characterized by downward displacement of the cerebellar tonsils into the cervical spinal canal. The aim of this study was to determine the volume of fourth ventricle and the length of herniated cerebellar tonsils in patients with Chiari type I malformation and control group using ImageJ program. Material and Methods: We retrospectively investigated magnetic resonance (MR) images from 27 patients with Chiari type I malformation (patient group). We also investigated MR images from 18 subjects as a control group who underwent an MRI complaining of headaches with the results showing no cranial or intracranial pathology. The volume and length were estimated using the ImageJ program Results: The mean volumes of fourth ventricle were determined as a 1.08±0.20 cm3 and 1.01±0.27 cm3 for control group and patient group, respectively. Ventricle volumes obtained from two groups were not statistically different (p>0.05). We found that the mean length of herniation was 9.48±3.22 mm in the patient group. We did not determine any relationship between age and any of these variables (volume and length) in both groups. Conclusion: This study has shown that the volume of fourth ventricle and the length of herniated cerebellar tonsils can be measured by ImageJ program. We think that when correlated with clinical findings, these measurements may contribute to the evaluation of Chiari type I malformation cases. Key words: Arnold-Chiari Malformation; Magnetic Resonance Imaging; Fourth Ventricle.

Kaynakça

  • Elster AD, Chen MY. Chiari I malformations: Clinical and radiologic reappraisal. Radiology 1992;183:347-53.
  • Chiari H. Über Veränderungen des kleinhirns infolge von hydrocephalie des grosshirns. Dtsch Med Wochenschr 1891;17:1172-75.
  • Atkinson JL, Weinshenker BG, Miller GM, Piedras DG, Mokri B. Acquired chiari I malformation secondary to spontaneous spinal cerebrospinal fluid leakage and chronic intracranial hypotension syndrome in seven cases. J Neurosurg 1998;88:237-42.
  • Chumas PD, Armstrong DC, Drake JM, Kulkarni AV, Hoffman HJ, Humphreys RP et al. Tonsillar herniation: The rule rather than the exception after lumboperitoneal shunting in the pediatric population. J Neurosurg 1993;78:568-73.
  • Lee M, Rezai AR, Wisoff JH. Acquired chiari-I malformation and hydromyelia secondary to a giant craniopharyngioma. Pediatr Neurosurg 1995;22:251-4.
  • Milhorat TH, Bolognese PA, Nishikawa M, McDonnell NB, Francomano CA. Syndrome of occipitoatlantoaxial hypermobility, cranial settling, and chiari malformation type I in patients with hereditary disorders of connective tissue. J Neurosurg Spine 2007;7:601-9.
  • Tubbs RS, Hill M, Loukas M, Shoja MM, Oakes WJ. Volumetric analysis of the posterior cranial fossa in a family with four generations of the chiari malformation type I. J Neurosurg Pediatrics 2008;1:21-4
  • Milhorat TH, Chou MW, Trinidad EM, Kula RW, Mandell M, Wolpert C, et al. Chiari I malformation redefined: Clinical and radiographic findings for 364 symptomatic patients. Neurosurgery 1999;44:1005–17.
  • Vurdem ÜE, Acer N, Ertekin T, Savranlar A, İnci MF. Analysis of the volumes of the posterior cranial fossa, cerebellum, and herniated tonsils using the stereological methods in patients with chiari type I Malformation. Scientific 10.1100/2012/616934 (in press) DOI:
  • Furtado SV, Reddy K, Hegde AS. Posterior fossa morphometry in symptomatic pediatric and adult chiari I malformation. J Clin Neurosci 2009;16:1449-54.
  • Milhorat TH, Nishikawa M, Kula RW, Dlugacz YD. Mechanisms of cerebellar tonsil herniation in patients with chiari malformations as guide to clinical management. Acta Neurochir (Wien) 2010;152:1117-27.
  • Wu YW, Chin CT, Chan KM, Barkovich AJ, Ferriero DM. et al. Pediatric chiari I malformations: Do clinical and 1999;53:1271-6. correlate. Neurology
  • Yassari R, Frim D. Evaluation and management of the chiari malformation type 1 for the primary care pediatrician. Pediatr Clin North Am 2004;51:477-90.
  • Cartlidge NEF, Al Hakim M, Bradley WG. Disorders of bones, joints, ligaments, cartilage, and meninges. In: Bradley WG, Daroff RB, Fenichel GM, Marsden CD, ed(s). Neurology in Clinical Practice. 2nd ed. Boston: Butterworth-Heinemann, 1996:1793-1822.
  • Stovner LJ, Bergan U, Nilsen G, Sjaastad O. Posterior cranial fossa dimensions in the chiari I malformation: Relation to pathogenesis and clinical presentation. Neuroradiology 1993;35:113-8.
  • Badie B, Mendoza D, Batzdorf U. Posterior fossa volume and response to suboccipital decompression in patients with chiari I malformation. Neurosurgery 1995;37:214–8.
  • Nishikawa M, Sakamoto H, Hakuba A, Nakanishi N, Inoue Y. Pathogenesis of chiari malformation: A morphometric study of the posterior cranial fossa. J Neurosurg 1997;86:40–7.
  • Solomon S, Masdeu JC. Neurology. In: Kaplan HI, Sadock BJ, ed(s). Comprehensive Textbook of Psychiatry. 5th ed. Baltimore, Marynland 1989:171.
  • Jack CR, Kokmen E, Onofrio BM. Spontaneous decompression of syringomyelia: MRI findings. Case report. J Neurosurgery 1991;74:283-6.
  • Schady W, Metcalfe RA, Butler P. The incidence of craniocervical bony anomalies in the adult chiari malformation. J Neurol Sci 1987;82:193-203.
  • Barkovich, AJ, Wippold FJ, Sherman JL, Citrin CM. Significance of cerebellar tonsillar position on MR. AJNR Am J Neuroradiol 1986;7:795-9.
  • Trigylidas T. Baronia B, Vassilyadi M, Ventureyra EC. Posterior fossa dimension and volume estimates in pediatric patients with chiari I malformations. Childs Nerv Syst 2008;24:329-36
  • Sullivan EV, Deshmukh A, Desmond JE, Mathalon DH, Rosenbloom MJ, Lim KO, et al. Contribution of alcohol abuse to cerebellar volume deficits in men with schizophrenia. Arch Gen Psychiatry 2000;57:894-902.
  • Dalaker TO, Zivadinov R, Ramasamy DP, Beyer MK, Alves G, Bronnick KS, et al. Ventricular enlargement and mild cognitive impairment in early Parkinson’s disease. Mov Disord 2011;26:297-301.
  • Messina D, Cerasa A, Condino F, Arabia G, Novellino F, Nicoletti G, et al. Patterns of brain atrophy in Parkinson's disease, progressive supranuclear palsy and multiple system atrophy. Parkinsonism Relat Disord 2011;17:172-6
  • Acer N, Uğurlu N, Uysal DD, Unur E, Turgut M, Camurdanoğlu M. Comparison of two volumetric techniques for estimating volume of intracerebral ventricles using magnetic resonance imaging: A stereological study. Anat Sci Int 2010;85:131-9.

Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin ve Herniasyon Uzunluğunun ImageJ Programı ile Hesaplanması

Yıl 2012, Cilt: 19 Sayı: 4, 249 - 255, 01.08.2012

Öz

Amaç: Chiari malformasyonu tip 1 (CMT1), tonsilla serebelli'nin aşağıya, spinal kanala doğru herniyasyonu ile karakterize konjenital bir anomalidir. Bu çalışmanın amacı Chiari malformasyonu tip 1'li hastalarda ve kontrol grubunda ImageJ programı kullanarak 4. ventrikülün hacmini ve herniasyon gösteren tonsilla serebelli uzunluğunu belirlemektir. Gereç ve Yöntem: CMT1'li 27 hastanın manyetik rezonans (MR) görüntüleri retrospektif olarak incelendi (hasta grubu). Aynı zamanda baş ağrısı nedeniyle MR'ı çekilen, kranial ve intrakranial hiç bir patolojisi bulunmayan 18 kişi de kontrol grubu olarak incelendi. Hacim ve uzunluk değerleri ImageJ programı kullanılarak hesaplandı. Bulgular: 4. ventrikülün ortalama hacmi kontrol grubunda 1.08±0.20 cm3, hasta grubunda 1.01±0.27 cm3 olarak belirlendi. İki gruptan elde edilen ventrikül hacimleri istatistiksel olarak farklı değildi (p>0.05). Hasta grubunda ortalama herniasyon uzunluğu 9.48±3.22 mm olarak bulundu. Her iki grupta da yaş ile diğer değişkenler (hacim ve uzunluk) arasında herhangi bir ilişki belirlenmedi (p>0.05). Sonuç: Bu çalışma 4. ventrikül hacminin ve herniasyon gösteren tonsilla serebelli uzunluğunun Image J programı ile ölçülebileceğini göstermiştir. Klinik bulgular ile korele edildiğinde bu ölçümlerin CMT1'li vakaların değerlendirmesine katkıda bulunacağını düşünmekteyiz. Anahtar kelimeler: Arnold-Chiari Malformasyon; Manyetik Rezonans Görüntüleme; Dördüncü Ventrikül.

Kaynakça

  • Elster AD, Chen MY. Chiari I malformations: Clinical and radiologic reappraisal. Radiology 1992;183:347-53.
  • Chiari H. Über Veränderungen des kleinhirns infolge von hydrocephalie des grosshirns. Dtsch Med Wochenschr 1891;17:1172-75.
  • Atkinson JL, Weinshenker BG, Miller GM, Piedras DG, Mokri B. Acquired chiari I malformation secondary to spontaneous spinal cerebrospinal fluid leakage and chronic intracranial hypotension syndrome in seven cases. J Neurosurg 1998;88:237-42.
  • Chumas PD, Armstrong DC, Drake JM, Kulkarni AV, Hoffman HJ, Humphreys RP et al. Tonsillar herniation: The rule rather than the exception after lumboperitoneal shunting in the pediatric population. J Neurosurg 1993;78:568-73.
  • Lee M, Rezai AR, Wisoff JH. Acquired chiari-I malformation and hydromyelia secondary to a giant craniopharyngioma. Pediatr Neurosurg 1995;22:251-4.
  • Milhorat TH, Bolognese PA, Nishikawa M, McDonnell NB, Francomano CA. Syndrome of occipitoatlantoaxial hypermobility, cranial settling, and chiari malformation type I in patients with hereditary disorders of connective tissue. J Neurosurg Spine 2007;7:601-9.
  • Tubbs RS, Hill M, Loukas M, Shoja MM, Oakes WJ. Volumetric analysis of the posterior cranial fossa in a family with four generations of the chiari malformation type I. J Neurosurg Pediatrics 2008;1:21-4
  • Milhorat TH, Chou MW, Trinidad EM, Kula RW, Mandell M, Wolpert C, et al. Chiari I malformation redefined: Clinical and radiographic findings for 364 symptomatic patients. Neurosurgery 1999;44:1005–17.
  • Vurdem ÜE, Acer N, Ertekin T, Savranlar A, İnci MF. Analysis of the volumes of the posterior cranial fossa, cerebellum, and herniated tonsils using the stereological methods in patients with chiari type I Malformation. Scientific 10.1100/2012/616934 (in press) DOI:
  • Furtado SV, Reddy K, Hegde AS. Posterior fossa morphometry in symptomatic pediatric and adult chiari I malformation. J Clin Neurosci 2009;16:1449-54.
  • Milhorat TH, Nishikawa M, Kula RW, Dlugacz YD. Mechanisms of cerebellar tonsil herniation in patients with chiari malformations as guide to clinical management. Acta Neurochir (Wien) 2010;152:1117-27.
  • Wu YW, Chin CT, Chan KM, Barkovich AJ, Ferriero DM. et al. Pediatric chiari I malformations: Do clinical and 1999;53:1271-6. correlate. Neurology
  • Yassari R, Frim D. Evaluation and management of the chiari malformation type 1 for the primary care pediatrician. Pediatr Clin North Am 2004;51:477-90.
  • Cartlidge NEF, Al Hakim M, Bradley WG. Disorders of bones, joints, ligaments, cartilage, and meninges. In: Bradley WG, Daroff RB, Fenichel GM, Marsden CD, ed(s). Neurology in Clinical Practice. 2nd ed. Boston: Butterworth-Heinemann, 1996:1793-1822.
  • Stovner LJ, Bergan U, Nilsen G, Sjaastad O. Posterior cranial fossa dimensions in the chiari I malformation: Relation to pathogenesis and clinical presentation. Neuroradiology 1993;35:113-8.
  • Badie B, Mendoza D, Batzdorf U. Posterior fossa volume and response to suboccipital decompression in patients with chiari I malformation. Neurosurgery 1995;37:214–8.
  • Nishikawa M, Sakamoto H, Hakuba A, Nakanishi N, Inoue Y. Pathogenesis of chiari malformation: A morphometric study of the posterior cranial fossa. J Neurosurg 1997;86:40–7.
  • Solomon S, Masdeu JC. Neurology. In: Kaplan HI, Sadock BJ, ed(s). Comprehensive Textbook of Psychiatry. 5th ed. Baltimore, Marynland 1989:171.
  • Jack CR, Kokmen E, Onofrio BM. Spontaneous decompression of syringomyelia: MRI findings. Case report. J Neurosurgery 1991;74:283-6.
  • Schady W, Metcalfe RA, Butler P. The incidence of craniocervical bony anomalies in the adult chiari malformation. J Neurol Sci 1987;82:193-203.
  • Barkovich, AJ, Wippold FJ, Sherman JL, Citrin CM. Significance of cerebellar tonsillar position on MR. AJNR Am J Neuroradiol 1986;7:795-9.
  • Trigylidas T. Baronia B, Vassilyadi M, Ventureyra EC. Posterior fossa dimension and volume estimates in pediatric patients with chiari I malformations. Childs Nerv Syst 2008;24:329-36
  • Sullivan EV, Deshmukh A, Desmond JE, Mathalon DH, Rosenbloom MJ, Lim KO, et al. Contribution of alcohol abuse to cerebellar volume deficits in men with schizophrenia. Arch Gen Psychiatry 2000;57:894-902.
  • Dalaker TO, Zivadinov R, Ramasamy DP, Beyer MK, Alves G, Bronnick KS, et al. Ventricular enlargement and mild cognitive impairment in early Parkinson’s disease. Mov Disord 2011;26:297-301.
  • Messina D, Cerasa A, Condino F, Arabia G, Novellino F, Nicoletti G, et al. Patterns of brain atrophy in Parkinson's disease, progressive supranuclear palsy and multiple system atrophy. Parkinsonism Relat Disord 2011;17:172-6
  • Acer N, Uğurlu N, Uysal DD, Unur E, Turgut M, Camurdanoğlu M. Comparison of two volumetric techniques for estimating volume of intracerebral ventricles using magnetic resonance imaging: A stereological study. Anat Sci Int 2010;85:131-9.
Toplam 26 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Tolga Ertekin Bu kişi benim

Niyazi Acer Bu kişi benim

Ümit Erkan Vurdem Bu kişi benim

Erdoğan Unur Bu kişi benim

Mahmut Çay Bu kişi benim

Yayımlanma Tarihi 1 Ağustos 2012
Yayımlandığı Sayı Yıl 2012 Cilt: 19 Sayı: 4

Kaynak Göster

APA Ertekin, T., Acer, N., Vurdem, Ü. E., Unur, E., vd. (2012). Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin ve Herniasyon Uzunluğunun ImageJ Programı ile Hesaplanması. Journal of Turgut Ozal Medical Center, 19(4), 249-255.
AMA Ertekin T, Acer N, Vurdem ÜE, Unur E, Çay M. Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin ve Herniasyon Uzunluğunun ImageJ Programı ile Hesaplanması. Turgut Özal Tıp Merk Derg. Ağustos 2012;19(4):249-255.
Chicago Ertekin, Tolga, Niyazi Acer, Ümit Erkan Vurdem, Erdoğan Unur, ve Mahmut Çay. “Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin Ve Herniasyon Uzunluğunun ImageJ Programı Ile Hesaplanması”. Journal of Turgut Ozal Medical Center 19, sy. 4 (Ağustos 2012): 249-55.
EndNote Ertekin T, Acer N, Vurdem ÜE, Unur E, Çay M (01 Ağustos 2012) Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin ve Herniasyon Uzunluğunun ImageJ Programı ile Hesaplanması. Journal of Turgut Ozal Medical Center 19 4 249–255.
IEEE T. Ertekin, N. Acer, Ü. E. Vurdem, E. Unur, ve M. Çay, “Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin ve Herniasyon Uzunluğunun ImageJ Programı ile Hesaplanması”, Turgut Özal Tıp Merk Derg, c. 19, sy. 4, ss. 249–255, 2012.
ISNAD Ertekin, Tolga vd. “Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin Ve Herniasyon Uzunluğunun ImageJ Programı Ile Hesaplanması”. Journal of Turgut Ozal Medical Center 19/4 (Ağustos 2012), 249-255.
JAMA Ertekin T, Acer N, Vurdem ÜE, Unur E, Çay M. Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin ve Herniasyon Uzunluğunun ImageJ Programı ile Hesaplanması. Turgut Özal Tıp Merk Derg. 2012;19:249–255.
MLA Ertekin, Tolga vd. “Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin Ve Herniasyon Uzunluğunun ImageJ Programı Ile Hesaplanması”. Journal of Turgut Ozal Medical Center, c. 19, sy. 4, 2012, ss. 249-55.
Vancouver Ertekin T, Acer N, Vurdem ÜE, Unur E, Çay M. Chiari Tip 1 Malformasyonlu Hastalarda Dördüncü Ventrikül Hacminin ve Herniasyon Uzunluğunun ImageJ Programı ile Hesaplanması. Turgut Özal Tıp Merk Derg. 2012;19(4):249-55.