An investigation of patients with acute peripheral facial palsy with regard to Lyme disease

Yıl 2003, Cilt: 10 Sayı: 4, 143 - 147, 15.08.2003

İrfan Kaygusuz Turgut Karlıdağ Erol Keleş Şinasi Yalçın Ayça Tazegül Ahmet Gödekmerdan

Öz

Objectives: We investigated the role of Borrelia burgdorferi in the etiology of idiopathic acute periph­ eral facial palsy.Patients and Methods: Nineteen patients 15 females, 4 males; mean age 38 years; range 14 to 61 years with acute peripheral facial palsy were studied.Following routine otolaryngologic examination, ali the patients undervvent taste, Schirmer, and stapedial reflex tests to evaluate the level of the palsy.Laboratory examination included routine biochemistry analysis, serum C-reactive protein, rheumatoid factor, and erythrocyte sedimentation rate. M i-B o rre lia burgdorferi IgM and IgG antibodies were sought by ELISA in venous blood samples.Results: Of the patient group, acute facial palsy was localized on the right in 12 patients 63.2% , and on the left in seven patients 36.8% . None of the patients had bilateral involvement. No IgM or IgG seropositivity for Borrelia burgdorferi was detected in the serum samples.Conclusion: İn highly endemic areas, it maybe helpful to detect or even to eliminate Lyme disease through screening of serum in patients with acute peripheral palsy.

Anahtar Kelimeler

Antibodies, bacterial/blood/analysis, Borrelia burgdorferi group/isolation & purification, facial paralysis/diagnosis/etiology, immunoglobulin G/analysis, immunoglobulin M/analysis, Lyme disease/diagnosis/immunology

Akut periferik fasyal paralizili olguların Lyme hastalığı açısından incelenmesi

Öz

Amaç: Akut periferik fasyal paralizinin etyolojisindeBorrela burgdorferi’nin etken olup olmadığı arafltır ı l d ı .Hastalar ve Yöntemler: Çalıflmaya akut periferik fasyal paralizili 19 hasta alındı. Tüm olgularda rutin KBBmuayenesinin ardından, tat, Schirmer ve stapedialrefleks testleri ile paralizinin derecesi değerlendirildi.Tüm hastalarda rutin biyokimyasal incelemeler yapıldı; serum reaktif protein, romatoid faktör düzeyleri ve sedimantasyon hızları belirlendi. Hastalardanalınan venöz kan örneklerinde ELISA yöntemiyleBorrelia burgdorferi için IgM ve IgG antikorları arafltırıldı.Bulgular: On iki hastada %63.2 sağ, yedisinde %36.8 sol akut periferik fasyal paralizi belirlendi;hiçbirinde iki taraflı paralizi yoktu. Hiçbir serumdaBorrelia burgdorferi için IgM ve IgG seropozitifliğinerastlanmadı.Sonuç: Yüksek derecede endemik bölgelerde, periferik fasyal paralizi ile baflvuran hastalarda, Lymehastalığını saptamak ya da dıfllamak için hasta serumlarının incelenmesi yararlı olabilir

Anahtar Kelimeler

Antikor , bakteriyel/kan/analiz, Borrelia burgdorferi/izolasyon ve purifikasyon, fasyal paralizi/tan›/etyoloji, immünglobulin G/analiz, immünglobulin M/analiz, Lyme hastalığıtan›/immünoloji.

Kaynakça

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