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Ultrasonography guided fine needle aspiration biopsy of parotid gland masses

Yıl 2004, Cilt: 13 Sayı: 1, 15 - 18, 10.02.2004

Öz

Objectives: Exact preoperative diagnosis of the parotid gland masses requires highly specific and sensitive diagnostic techniques. The specificity, sensitivity and accuracy of ultrasonography guided fine needle aspiration biopsy of the parotid gland mass­ es performed by an otolaryngologist and evaluated by a same cytopathologist are assessed.Patients and Methods: There were 46 female and 36 male patients. The mean age was 39 range: 18 to 74 years . Ultrasonography guided fine needle aspiration biopsies were performed and cytologic diagnoses were compared with the postoperative histopathologic findings of specimens.Results: İn our series 65 79% of the lesions were found to be benign and 17 21% malignant. There were one false negative and one false positive result. The sensitivity, specifity and accuracy rates are found to be 94.1%, 98.4% and 97.6% for parotid tumors, respectively.Conclusion: Ultrasonography guided fine needle aspiration biopsy of parotid gland masses have been proven to be a highly specific, sensitive and a safe preoperative diagnostic technique when performed by an experienced clinician and cytopathologist.

Kaynakça

  • Linsk JA. Aspiration cytology in Sweden: The Karolinska Group. Diagn Cytopathol 1985;1:332-5.
  • Weinberger MS, Rosenberg WW, Meurer WT, Robbins KT. Fine-needle aspiration of parotid gland lesions. Head Neck 1992;14:483-7.
  • Zurrida S, Alasio L, Tradati N, Bartoli C, Chiesa F, Pilotti S. Fine-needle aspiration of parotid masses. Cancer 1993;72:2306-11.
  • Frable MA, Frable WJ. Fine-needle aspiration biopsy revisited. Laryngoscope 1982;92:1414-8.
  • Atula T, Greenman R, Laippala P, Klemi PJ. Fine-nee- dle aspiration biopsy in the diagnosis of parotid gland lesions: evaluation of 438 biopsies. Diagn Cytopathol 1996;15:185-90.
  • Amedee RG, Dhurandhar NR. Fine-needle aspiration biopsy. Laryngoscope 2001;111:1551-7.
  • Megerian CA, Maniglia AJ. Parotidectomy: a ten year experience with fine needle aspiration and frozen sec- tion biopsy correlation. Ear Nose Throat J 1994;73:377- 80.
  • Cohen MB, Ljung BM, Boles R. Salivary gland tumors. Fine-needle aspiration vs frozen-section diagnosis. Arch Otolaryngol Head Neck Surg 1986;112:867-9.
  • Candel A, Gattuso P, Reddy V, Matz G, Castelli M. Is fine needle aspiration biopsy of salivary gland masses really necessary? Ear Nose Throat J 1993;72:485-9.
  • Heller KS, Dubner S, Chess Q, Attie JN. Value of fine needle aspiration biopsy of salivary gland masses in clinical decision-making. Am J Surg 1992;164:667-70.
  • Dee S, Masood S, Issacs JH Jr, Hardy NM. Cytomorphologic features of salivary duct carcinoma on fine needle aspiration biopsy. A case report. Acta Cytol 1993;37:539-42.
  • O’Dwyer P, Farrar WB, James AG, Finkelmeier W, McCabe DP. Needle aspiration biopsy of major sali- vary gland tumors. Its value. Cancer 1986;57:554-7.
  • Cuhruk Ç, Aktürk T, Akıner M. Majör tükrük bezi kitlelerinin tanısında ultrasonografi ve sialografinin değeri. In: XX. Türk ORL Ulusal Kongre Kitabı; 9-13 Ekim 1989; Girne, Kıbrıs. İstanbul: Erol Ofset; 1989. s. 4-5.
  • McIvor NP, Freeman JL, Salem S, Elden L, Noyek AM, Bedard YC. Ultrasonography and ultrasound-guided fine-needle aspiration biopsy of head and neck lesions: a surgical perspective. Laryngoscope 1994;104(6 Pt 1):669-74.
  • Frable MA, Frable WJ. Fine-needle aspiration biopsy of salivary glands. Laryngoscope 1991;101:245-9.
  • Zbaren P, Schar C, Hotz MA, Loosli H. Value of fine- needle aspiration cytology of parotid gland masses. Laryngoscope 2001;111(11 Pt 1):1989-92.
  • Raymond MR, Yoo JH, Heathcote JG, McLachlin CM, Lampe HB. Accuracy of fine-needle aspiration biopsy for Warthin’s tumours. J Otolaryngol 2002;31:263-70.
  • Yılmaz O, Saatçi M, Aktürk T, Cuhruk Ç. Parotis kitlelerinde iğne aspirasyon biopsisi. KBB ve Baş Boyun Cerrahisi Dergisi 1993;1:72-5.
  • Zajicek J, Eneroth CM, Jakobsson P. Aspiration biopsy of salivary gland tumors. VI. Morphologic studies on smears and histologic sections from mucoepidermoid carcinoma. Acta Cytol 1976;20:35-41.
  • Gunhan O, Celasun B, Safali M, Aksu A, Guler M, Onder T, et al. Fine needle aspiration cytology of malignant lymphoepithelial lesion of the salivary gland. A report of two cases. Acta Cytol 1994;38:751-4.
  • Costas A, Castro P, Martin-Granizo R, Monje F, Marron C, Amigo A. Fine needle aspiration biopsy (FNAB) for lesions of the salivary glands. Br J Oral Maxillofac Surg 2000;38:539-42.
  • Schroder U, Eckel HE, Rasche V, Arnold G, Ortmann M, Stennert E. Value of fine needle puncture cytology in neoplasms of the parotid gland. HNO 2000;48:421-9. [Abstract]

Parotis bezi kitlelerinde ultrasonografi eşliğinde ince iğne aspirasyon biyopsisi

Yıl 2004, Cilt: 13 Sayı: 1, 15 - 18, 10.02.2004

Öz

Amaç: Parotis bezi kitlelerinde, ameliyat öncesi dönemde doğru histolojik tanıyı koyabilecek, yükseksensitivite ve spesifite değerlerine sahip bir tanı yöntemine ihtiyaç vardır. Tek bir kulak burun boğaz uzmanı tarafından yapılan ve aynı sitopatolozun değerlendirdiği parotis bezi kitlelerinden ultrasonografi eşliğinde ince iğne aspirasyon biyopsisi sonuçları araştırıldı.Hastalar ve Yöntemler: Çalışmaya 82 hasta dahil edildi. hastalara tek bir kulak burun boğaz uzmanı tarafından ultrasonografi eşliğinde ince iğne aspirasyon yapıldı ve aynı sitopatolog tarafından değerlendirildi. Sitolojik tanı,ameliyat sonrası histopatolojik sonuçlar ile karşılaştırıldı.Bulgular: Hastaların 65’inin %79 benign, 17’sinin %21 malign olduğu saptandı. Aspirasyon biyopsisileriile patoloji spesmenleri sonuçları karşılaştırıldığında biryalancı negatif ve bir yalancı pozitif sonuç olduğu görüldü. Parotis tümörleri için sensivite, spesifite ve doğrulukoranları sırasıyla %94.1, 98.4 ve 97.6 olarak bulundu.Sonuç: Parotis bez kitlelerde tek bir uygulayıcı tarafından yapılan ve aynı sitopatolog tarafından değerlendirilen ultrasonografi eşliğinde ince iğne aspirasyon biyopsisinin yüksek oranda spesifik, sensitif vegüvenli olduğu saptandı

Kaynakça

  • Linsk JA. Aspiration cytology in Sweden: The Karolinska Group. Diagn Cytopathol 1985;1:332-5.
  • Weinberger MS, Rosenberg WW, Meurer WT, Robbins KT. Fine-needle aspiration of parotid gland lesions. Head Neck 1992;14:483-7.
  • Zurrida S, Alasio L, Tradati N, Bartoli C, Chiesa F, Pilotti S. Fine-needle aspiration of parotid masses. Cancer 1993;72:2306-11.
  • Frable MA, Frable WJ. Fine-needle aspiration biopsy revisited. Laryngoscope 1982;92:1414-8.
  • Atula T, Greenman R, Laippala P, Klemi PJ. Fine-nee- dle aspiration biopsy in the diagnosis of parotid gland lesions: evaluation of 438 biopsies. Diagn Cytopathol 1996;15:185-90.
  • Amedee RG, Dhurandhar NR. Fine-needle aspiration biopsy. Laryngoscope 2001;111:1551-7.
  • Megerian CA, Maniglia AJ. Parotidectomy: a ten year experience with fine needle aspiration and frozen sec- tion biopsy correlation. Ear Nose Throat J 1994;73:377- 80.
  • Cohen MB, Ljung BM, Boles R. Salivary gland tumors. Fine-needle aspiration vs frozen-section diagnosis. Arch Otolaryngol Head Neck Surg 1986;112:867-9.
  • Candel A, Gattuso P, Reddy V, Matz G, Castelli M. Is fine needle aspiration biopsy of salivary gland masses really necessary? Ear Nose Throat J 1993;72:485-9.
  • Heller KS, Dubner S, Chess Q, Attie JN. Value of fine needle aspiration biopsy of salivary gland masses in clinical decision-making. Am J Surg 1992;164:667-70.
  • Dee S, Masood S, Issacs JH Jr, Hardy NM. Cytomorphologic features of salivary duct carcinoma on fine needle aspiration biopsy. A case report. Acta Cytol 1993;37:539-42.
  • O’Dwyer P, Farrar WB, James AG, Finkelmeier W, McCabe DP. Needle aspiration biopsy of major sali- vary gland tumors. Its value. Cancer 1986;57:554-7.
  • Cuhruk Ç, Aktürk T, Akıner M. Majör tükrük bezi kitlelerinin tanısında ultrasonografi ve sialografinin değeri. In: XX. Türk ORL Ulusal Kongre Kitabı; 9-13 Ekim 1989; Girne, Kıbrıs. İstanbul: Erol Ofset; 1989. s. 4-5.
  • McIvor NP, Freeman JL, Salem S, Elden L, Noyek AM, Bedard YC. Ultrasonography and ultrasound-guided fine-needle aspiration biopsy of head and neck lesions: a surgical perspective. Laryngoscope 1994;104(6 Pt 1):669-74.
  • Frable MA, Frable WJ. Fine-needle aspiration biopsy of salivary glands. Laryngoscope 1991;101:245-9.
  • Zbaren P, Schar C, Hotz MA, Loosli H. Value of fine- needle aspiration cytology of parotid gland masses. Laryngoscope 2001;111(11 Pt 1):1989-92.
  • Raymond MR, Yoo JH, Heathcote JG, McLachlin CM, Lampe HB. Accuracy of fine-needle aspiration biopsy for Warthin’s tumours. J Otolaryngol 2002;31:263-70.
  • Yılmaz O, Saatçi M, Aktürk T, Cuhruk Ç. Parotis kitlelerinde iğne aspirasyon biopsisi. KBB ve Baş Boyun Cerrahisi Dergisi 1993;1:72-5.
  • Zajicek J, Eneroth CM, Jakobsson P. Aspiration biopsy of salivary gland tumors. VI. Morphologic studies on smears and histologic sections from mucoepidermoid carcinoma. Acta Cytol 1976;20:35-41.
  • Gunhan O, Celasun B, Safali M, Aksu A, Guler M, Onder T, et al. Fine needle aspiration cytology of malignant lymphoepithelial lesion of the salivary gland. A report of two cases. Acta Cytol 1994;38:751-4.
  • Costas A, Castro P, Martin-Granizo R, Monje F, Marron C, Amigo A. Fine needle aspiration biopsy (FNAB) for lesions of the salivary glands. Br J Oral Maxillofac Surg 2000;38:539-42.
  • Schroder U, Eckel HE, Rasche V, Arnold G, Ortmann M, Stennert E. Value of fine needle puncture cytology in neoplasms of the parotid gland. HNO 2000;48:421-9. [Abstract]
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

Yücel Akbaş Bu kişi benim

Evrim Ünsal Tuna Bu kişi benim

Alp Demireller Bu kişi benim

Hasan Özcan Bu kişi benim

Cemil Ekinci Bu kişi benim

Yayımlanma Tarihi 10 Şubat 2004
Yayımlandığı Sayı Yıl 2004 Cilt: 13 Sayı: 1

Kaynak Göster

APA Akbaş, Y., Ünsal Tuna, E., Demireller, A., Özcan, H., vd. (2004). Ultrasonography guided fine needle aspiration biopsy of parotid gland masses. The Turkish Journal of Ear Nose and Throat, 13(1), 15-18.
AMA Akbaş Y, Ünsal Tuna E, Demireller A, Özcan H, Ekinci C. Ultrasonography guided fine needle aspiration biopsy of parotid gland masses. Tr-ENT. Şubat 2004;13(1):15-18.
Chicago Akbaş, Yücel, Evrim Ünsal Tuna, Alp Demireller, Hasan Özcan, ve Cemil Ekinci. “Ultrasonography Guided Fine Needle Aspiration Biopsy of Parotid Gland Masses”. The Turkish Journal of Ear Nose and Throat 13, sy. 1 (Şubat 2004): 15-18.
EndNote Akbaş Y, Ünsal Tuna E, Demireller A, Özcan H, Ekinci C (01 Şubat 2004) Ultrasonography guided fine needle aspiration biopsy of parotid gland masses. The Turkish Journal of Ear Nose and Throat 13 1 15–18.
IEEE Y. Akbaş, E. Ünsal Tuna, A. Demireller, H. Özcan, ve C. Ekinci, “Ultrasonography guided fine needle aspiration biopsy of parotid gland masses”, Tr-ENT, c. 13, sy. 1, ss. 15–18, 2004.
ISNAD Akbaş, Yücel vd. “Ultrasonography Guided Fine Needle Aspiration Biopsy of Parotid Gland Masses”. The Turkish Journal of Ear Nose and Throat 13/1 (Şubat 2004), 15-18.
JAMA Akbaş Y, Ünsal Tuna E, Demireller A, Özcan H, Ekinci C. Ultrasonography guided fine needle aspiration biopsy of parotid gland masses. Tr-ENT. 2004;13:15–18.
MLA Akbaş, Yücel vd. “Ultrasonography Guided Fine Needle Aspiration Biopsy of Parotid Gland Masses”. The Turkish Journal of Ear Nose and Throat, c. 13, sy. 1, 2004, ss. 15-18.
Vancouver Akbaş Y, Ünsal Tuna E, Demireller A, Özcan H, Ekinci C. Ultrasonography guided fine needle aspiration biopsy of parotid gland masses. Tr-ENT. 2004;13(1):15-8.