BibTex RIS Kaynak Göster

Rhinocerebral mucormycosis: a report of two cases

Yıl 2005, Cilt: 15 Sayı: 1, 40 - 44, 10.03.2005

Öz

Rhinocerebral mucormycosis is an aggressive fungal disease that involves the nose, paranasal sinuses, orbit and Central nervous system. İt may rapidly be fatal.This infection usually occurs secondary to immune suppression, diabetic ketoacidosis, and prolonged use of antibiotics, steroids, and cytotoxic drugs. Management of the condition consists of treatment of underlying dis­ ease and surgical debridement combined with intra- venous amphotericin B. This paper presents two patients with rhinocerebral mucormycosis, both suffer- ing from diabetes. Complete recovery was achieved in one patient with surgical debridement of necrotic tissue combined with systemic antifungal treatment, whereas in the other, the disease was complicated with subarachnoid hemorrhage and the patient died on the third day of treatment.

Kaynakça

  • Hafız G, Aktaş E, Uluğ T, Başerer N, Tınaz M, Ergen M, Kılıç H. Rinoserebral mukormukozis. Türk Otola- rengoloji Arşivi 1999;37:46-50.
  • Damante JH, Fleury RN. Oral and rhinoorbital mucormycosis: case report. J Oral Maxillofac Surg 1998;56:267-71.
  • Erkan M, Ceroğlu S, Cantürk M, Kandemir O. Rinose- rebral mukormukozis. KBB Postası 1993;2:7-9.
  • Peterson KL, Wang M, Canalis RF, Abemayor E. Rhinocerebral mucormycosis: evolution of the disease and treatment options. Laryngoscope 1997;107:855-62.
  • Boelaert JR. Mucormycosis (zygomycosis): is there news for the clinician? J Infect 1994;28 Suppl 1:1-6.
  • Gregory JE, Golden A, Haymaker W. Mucormycosis of the central nervous system. Bull Johns Hopkins Hosp 1943;73:405-15.
  • deShazo RD, O’Brien M, Chapin K, Soto-Aguilar M, Gardner L, Swain R. A new classification and diagnos- tic criteria for invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 1997;123:1181-8.
  • Yohai RA, Bullock JD, Aziz AA, Markert RJ. Survival factors in rhino-orbital-cerebral mucormycosis. Surv Ophthalmol 1994;39:3-22.
  • Feeley MA, Righi PD, Davis TE, Greist A. Mucormycosis of the paranasal sinuses and septum. Otolaryngol Head Neck Surg 1999;120:750.
  • Coşkun H, Hızalan İ, Erişen L, Helvacı S, Baul O, Onan S. Rinoserebral mukormikozis, 2 olgu sunumu. In: XXVI. Ulusal Türk Otorinolarengoloji ve Baş Boyun Cerrahisi Kongresi (Özet Kitabı); 22-26 Eylül 2001; Antalya, Türkiye; 2001. s. 89-90.
  • Bhattacharyya AK, Deshpande AR, Nayak SR, Kirtane MV, Ingle MV, Vora IM. Rhinocerebral mucormycosis: an unusual case presentation. J Laryngol Otol 1992;106:48-9.
  • Özaksoy D, Günbay MU, Güneri A, Ceryan K, İkiz AO, Özen E ve ark. Dört olgu nedeniyle Rinoserebral mukormukozis: Klinik, radyolojik bulgular ve tedavi. Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi 1992;6:69-73.
  • Verma KK, Pandhi RK. Subcutaneous mucormycosis in a non-immunocompromised patient treated with potassium iodide. Acta Derm Venereol 1994;74:215-6.
  • Nussbaum ES, Hall WA. Rhinocerebral mucormycosis: changing patterns of disease. Surg Neurol 1994;41:152- 6.
  • Platauf AP. Mycosis mucorina. Virchows Archiv: An International Journal of Pathology 1885;102:543-64.
  • Mazurat RD, Goldman BM. Prosthodontic rehabilita- tion of a patient with mucormycosis. J Can Dent Assoc 1992;58:571-3.
  • Blitzer A, Lawson W, Meyers BR, Biller HF. Patient survival factors in paranasal sinus mucormycosis. Laryngoscope 1980;90:635-48.

Rinoserebral mukormikozis: İki olgu sunumu

Yıl 2005, Cilt: 15 Sayı: 1, 40 - 44, 10.03.2005

Öz

Rinoserebral mukormikozis burnu, paranazal si- nüsleri, orbitayı ve merkezi sinir sistemini tutan ag- resif seyirli fungal bir hastalıktır ve çok kısa sürede hızla ölümcül olabilir. Bu enfeksiyon genellikle ba- ğışıklık sisteminin baskılanmasına, diyabetik keto- asidoza ve uzun süreli antibiyotik, steroid ve sito- toksik ilaç kullanımına bağlı olarak gelişir. Esas te- davi, altta yatan hastalığın tedavisi ve cerrahi deb- ridman ile birlikte intravenöz amfoterisin B kullanı- mından oluşur. Bu yazıda diyabetli iki hastada gö- rülen rinoserebral mukormikozis sunuldu. Bir olgu- da, nekrotik dokuların cerrahi debridmanı ve siste- mik antifungal tedavi ile tam iyileşme elde edildi. Diğer olgu ise, hastalığın subaraknoid kanama ile kötüleşmesi sonucu tedavinin üçüncü gününde ya- şamını yitirdi

Kaynakça

  • Hafız G, Aktaş E, Uluğ T, Başerer N, Tınaz M, Ergen M, Kılıç H. Rinoserebral mukormukozis. Türk Otola- rengoloji Arşivi 1999;37:46-50.
  • Damante JH, Fleury RN. Oral and rhinoorbital mucormycosis: case report. J Oral Maxillofac Surg 1998;56:267-71.
  • Erkan M, Ceroğlu S, Cantürk M, Kandemir O. Rinose- rebral mukormukozis. KBB Postası 1993;2:7-9.
  • Peterson KL, Wang M, Canalis RF, Abemayor E. Rhinocerebral mucormycosis: evolution of the disease and treatment options. Laryngoscope 1997;107:855-62.
  • Boelaert JR. Mucormycosis (zygomycosis): is there news for the clinician? J Infect 1994;28 Suppl 1:1-6.
  • Gregory JE, Golden A, Haymaker W. Mucormycosis of the central nervous system. Bull Johns Hopkins Hosp 1943;73:405-15.
  • deShazo RD, O’Brien M, Chapin K, Soto-Aguilar M, Gardner L, Swain R. A new classification and diagnos- tic criteria for invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg 1997;123:1181-8.
  • Yohai RA, Bullock JD, Aziz AA, Markert RJ. Survival factors in rhino-orbital-cerebral mucormycosis. Surv Ophthalmol 1994;39:3-22.
  • Feeley MA, Righi PD, Davis TE, Greist A. Mucormycosis of the paranasal sinuses and septum. Otolaryngol Head Neck Surg 1999;120:750.
  • Coşkun H, Hızalan İ, Erişen L, Helvacı S, Baul O, Onan S. Rinoserebral mukormikozis, 2 olgu sunumu. In: XXVI. Ulusal Türk Otorinolarengoloji ve Baş Boyun Cerrahisi Kongresi (Özet Kitabı); 22-26 Eylül 2001; Antalya, Türkiye; 2001. s. 89-90.
  • Bhattacharyya AK, Deshpande AR, Nayak SR, Kirtane MV, Ingle MV, Vora IM. Rhinocerebral mucormycosis: an unusual case presentation. J Laryngol Otol 1992;106:48-9.
  • Özaksoy D, Günbay MU, Güneri A, Ceryan K, İkiz AO, Özen E ve ark. Dört olgu nedeniyle Rinoserebral mukormukozis: Klinik, radyolojik bulgular ve tedavi. Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi 1992;6:69-73.
  • Verma KK, Pandhi RK. Subcutaneous mucormycosis in a non-immunocompromised patient treated with potassium iodide. Acta Derm Venereol 1994;74:215-6.
  • Nussbaum ES, Hall WA. Rhinocerebral mucormycosis: changing patterns of disease. Surg Neurol 1994;41:152- 6.
  • Platauf AP. Mycosis mucorina. Virchows Archiv: An International Journal of Pathology 1885;102:543-64.
  • Mazurat RD, Goldman BM. Prosthodontic rehabilita- tion of a patient with mucormycosis. J Can Dent Assoc 1992;58:571-3.
  • Blitzer A, Lawson W, Meyers BR, Biller HF. Patient survival factors in paranasal sinus mucormycosis. Laryngoscope 1980;90:635-48.
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Olgu Sunumu
Yazarlar

Burak Ömür Çakır Bu kişi benim

İbrahim Ercan Bu kişi benim

Şenol Civelek Bu kişi benim

Suat Turgut Bu kişi benim

Yayımlanma Tarihi 10 Mart 2005
Yayımlandığı Sayı Yıl 2005 Cilt: 15 Sayı: 1

Kaynak Göster

APA Çakır, B. Ö., Ercan, İ., Civelek, Ş., Turgut, S. (2005). Rhinocerebral mucormycosis: a report of two cases. The Turkish Journal of Ear Nose and Throat, 15(1), 40-44.
AMA Çakır BÖ, Ercan İ, Civelek Ş, Turgut S. Rhinocerebral mucormycosis: a report of two cases. Tr-ENT. Mart 2005;15(1):40-44.
Chicago Çakır, Burak Ömür, İbrahim Ercan, Şenol Civelek, ve Suat Turgut. “Rhinocerebral Mucormycosis: A Report of Two Cases”. The Turkish Journal of Ear Nose and Throat 15, sy. 1 (Mart 2005): 40-44.
EndNote Çakır BÖ, Ercan İ, Civelek Ş, Turgut S (01 Mart 2005) Rhinocerebral mucormycosis: a report of two cases. The Turkish Journal of Ear Nose and Throat 15 1 40–44.
IEEE B. Ö. Çakır, İ. Ercan, Ş. Civelek, ve S. Turgut, “Rhinocerebral mucormycosis: a report of two cases”, Tr-ENT, c. 15, sy. 1, ss. 40–44, 2005.
ISNAD Çakır, Burak Ömür vd. “Rhinocerebral Mucormycosis: A Report of Two Cases”. The Turkish Journal of Ear Nose and Throat 15/1 (Mart 2005), 40-44.
JAMA Çakır BÖ, Ercan İ, Civelek Ş, Turgut S. Rhinocerebral mucormycosis: a report of two cases. Tr-ENT. 2005;15:40–44.
MLA Çakır, Burak Ömür vd. “Rhinocerebral Mucormycosis: A Report of Two Cases”. The Turkish Journal of Ear Nose and Throat, c. 15, sy. 1, 2005, ss. 40-44.
Vancouver Çakır BÖ, Ercan İ, Civelek Ş, Turgut S. Rhinocerebral mucormycosis: a report of two cases. Tr-ENT. 2005;15(1):40-4.