Non-Hodgkin's lymphoma of the parotid gland

Yıl 2006, Cilt: 16 Sayı: 4, 183 - 188, 27.08.2006

Erdinç Aydın Volkan Akdoğan Hasan Yerli B. Handan Özdemir Beyhan Demirhan

Öz

Most of the primary malignant lymphomas of the salivary glands originate from the parotid gland. We presented two patients who were admitted with a painless mass in the parotid region and diagnosed to have lymphoma. Physical examination of a 66-year-old male patient showed a rela- tively mobile, painless, and firm mass at the inferior aspect of the right parotid gland. Ultrasonography, computed tomography CT , and magnetic resonance imaging MRI were performed and a needle biopsy was obtained from the solid lesion extending from the right parotid superficial lobe to the medial deep lobe. Pathological examination revealed large B-cell lymphoma. The patient was treated according to the CHOP chemotherapy protocol. The second patient had undergone surgery for orbital lymphoma and received CHOP chemotherapy. On physical examination, there was a painless mass in the parotid cauda on the left and a subcu- taneous lymph node, 0.5x1 cm in size, inferior to the parotid cauda. Computed tomography and MRI showed an irregu- larly contoured solid lesion, 2x1 cm in size, in the posteroin­ ferior aspect of the superficial lobe. Lymph node biopsy yielded a diagnosis of small celi malignant lymphoma. The patient was referred to the medical oncology department for staging, further investigation, and planning of the treatment.

Anahtar Kelimeler

Head and neck neoplasms/pathology, lymphoma, nonHodgkin/pathology, parotid neoplasms/pathology

Parotis bezi non-Hodgkin lenfoması

Öz

Tükürük bezi primer malign lenfomalarının çoğu parotis bezinden kaynaklanır. Bu yazıda, parotis bölgesinde ağ- rısız şişlik nedeniyle başvuran ve lenfoma tanısı konan iki hasta sunuldu. Altmış altı yaşındaki erkek hastanın muayenesinde sağ parotis bezi inferiorunda, nispeten hareketli, ağrısız, sert kıvamlı kitle saptandı. Ultrasonog- rafi, bilgisayarlı tomografi BT ve manyetik rezonans gö- rüntüleme MRG incelemelerinden sonra, sağ parotis bezi yüzeyel lobunda, medialde derin loba uzanan solid lezyondan iğne biyopsisi yapıldı ve patolojik inceleme ile büyük B-hücreli lenfoma tanısı kondu. Hastaya CHOP kemoterapi protokolü uygulandı. İkinci hasta daha önce orbital lenfoma nedeniyle ameliyat edilmiş ve CHOP ke- moterapisi görmüştü. Fizik muayenede solda, parotis be- zi kuyruğunda ağrısız kitle ve parotis kuyruğunun inferi- orunda, cilt altında olduğu izlenimi veren 0.5x1 cm çaplı lenf nodu palpe edildi. Bilgisayarlı tomografi ve MRG’de parotis bezi yüzeyel lobunda posteroinferior kesimde, düzensiz konturlu, 2x1 cm boyutlarında solid lezyon gö- rüldü. Lenf nodundan yapılan biyopsi sonucu küçük hüc- reli malign lenfoma tanısı konan hasta evrelendirme, ile- ri inceleme ve tedavisinin planlanması için tıbbi onkoloji bölümüne sevk edildi

Anahtar Kelimeler

Baş-boyun neoplazileri/patoloji: lenfoma, non-Hodgkin/patoloji, parotis neoplazisi/patoloji

Kaynakça

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