Endonasal approach for frontobasal malignant nerve sheath tumor: a case report

Yıl 2006, Cilt: 16 Sayı: 6, 269 - 272, 02.12.2006

Bernhard Shick Steffi Urbschat

Öz

Malignant peripheral nerve sheath tumors MPNST are rarely encountered in the paranasal sinuses and frontal skull base. We present histopathological find- ings, cytometric DNA measurements, and the prelimi- nary results of comparative genomic hybridization studies of a 46-year-old male patient with a frontobasal MPNST. The tumor was resected via the endonasal approach. No tumor recurrence was detected during a follow-up of three years. Rhinologists are being more frequently involved in endonasal tumor resection.

Anahtar Kelimeler

Nerve sheath neoplasms, nucleic acid hybridization, paranasal sinuses, skull base

Frontal bölge kafa tabanında malign sinir kılıfı tümörü için endonazal yaklaşım

Öz

Paranazal sinüsleri ve frontal bölge kafa tabanını et- kileyen malign periferik sinir kılıfı tümörlerine nadir rastlanır. Bu yazıda, frontobazal bölge malign perife- rik sinir kılıfı tümörü saptanan 46 yaflındak erkek hastanın histopatolojik bulguları, sitometrik DNA analizleri ve karflılafltırmalı genomik hibridizasyonun ilk sonuçları sunuldu. Tümör endonazal yaklaflımla çıkarıldı ve üç yıllık izlem sırasında nüksle karflılaflıl- madı. Rinologlar endonazal tümör cerrahisine gide- rek daha sık baflvurmaktadır

Anahtar Kelimeler

Sinir kılıfı tümörleri, nükleik asit hibridizasyon, paranazal sinus, kafa tabanı

Kaynakça

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