Isolated hypoglossal nerve paralysis: a case report

Yıl 2010, Cilt: 20 Sayı: 4, 205 - 209, 20.08.2010

Güçlü Kaan Beriat Hande Ezerarslan Sinan Kocatürk Enes Özyar

Öz

Cranial nerve paralysis is an uncommon complication of radiotherapy for head and neck carcinomas because cranial nerves are relatively resistant to radiation. The incidence of this complication has been declared to be 1-5% in different studies. Unlike the other cranial nerves, isolated hypoglossal nerve paralysis in patients who have been treated with radiotherapy for nasopharyngeal carcinomas is a worrisome sign of recurrence. We report a 45-year-old male patient admitted to our clinics with complaints of difficulty in moving his tongue and dysphasia five years after combined radiotherapy and chemotherapy for nasopharyngeal carcinoma. Recurrence of the tumor was thought to be the cause of the isolated hypoglossal nerve paralysis at first, however late toxicity of radiotherapy was found to be the etiological factor after detailed examinatons.

Anahtar Kelimeler

Hypoglossal nerve paralysis, nasopharynx carcinomas, radiotherapy

İzole hipoglossus sinir felci: Bir olgu sunumu

Öz

Kraniyal sinir paralizisi, kraniyal sinirlerin göreceli olarak radyasyona dirençli olmaları nedeni ile baş ve boyun kanserlerinde radyoterapinin nadir komplikas- yonu olarak, nadiren ortaya çıkar. Farklı çalışmalar- da bu komplikasyon oranı %1-5 olarak bildirilmiştir. Radyoterapi tedavisi almış nazofarenks karsinomlu hastalarda izole hipoglossus sinir felci, diğer alt kra- niyal sinir felçlerinin aksine nüksü düşündüren kaygı verici bir bulgudur. Bu yazıdanazofarenks karsinomu nedeniyle aldığı kombine radyoterapi ve kemote- rapiden beş yıl sonra dilini hareket ettirememe ve konuşma zorluğu yakınmaları ile kliniğimize başvu- ran 45 yaşında bir erkek hasta sunuldu. İlk olarak, izole hipoglossus felcinin tümör nüksüne bağlı olarak geliştiği düşünüldü, fakat yapılan detaylı incelemeler sonucunda etyolojik faktörün radyoterapinin geç tok- sisitesi olduğu görüldü

Anahtar Kelimeler

Nervus hipoglossus paralizisi, nazofarenks kanseri, radyoterapi

Kaynakça

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