BibTex RIS Kaynak Göster

Submandibular gland pleomorphic adenoma in a seven-year-old child: a case report

Yıl 2010, Cilt: 20 Sayı: 4, 210 - 213, 20.08.2010

Öz

Salivary gland neoplasms are rare in the pediatric age group. Pleomorphic adenomas in the submandibular gland are rarer. In this article, we present a seven-year-old female with a slowly growing mass in her right submandibular area. The firm, mobile and painless mass was about 2x3 cm in size and with bimanual palpation it was indiscriminated from the submandibular gland. Magnetic resonance imaging with contrast revealed a heterogeneous and minimally lobulated mass within the submandibular gland with clearly defined borders. Fine needle aspiration biopsy revealed a diagnosis of pleomorphic adenoma and we performed right submandibular gland excision under general anesthesia. The histopathological diagnosis was pleomorphic adenoma with sparse mitotic figures that may be interpreted as having a potential of malignant transformation. This patient who was followed up for one year without any complication is to our knowledge the youngest case cited in the English-language literature.

Kaynakça

  • Hockstein NG, Samadi DS, Gendron K, Carpentieri D, Wetmore RF. Pediatric submandibular triangle masses: a fifteen-year experience. Head Neck 2004;26:675-80.
  • Luna MA, Batsakis JG, el-Naggar AK. Salivary gland tumors in children. Ann Otol Rhinol Laryngol 1991; 100:869-71.
  • Guzzo M, Ferrari A, Marcon I, Collini P, Gandola L, Pizzi N, et al. Salivary gland neoplasms in children: the experience of the Istituto Nazionale Tumori of Milan. Pediatr Blood Cancer 2006;47:806-10.
  • Ellies M, Schaffranietz F, Arglebe C, Laskawi R. Tumors of the salivary glands in childhood and ado- lescence. J Oral Maxillofac Surg 2006;64:1049-58.
  • Ogata H, Ebihara S, Mukai K. Salivary gland neo- plasms in children. Jpn J Clin Oncol 1994;24:88-93.
  • Yıldırım G, Kuzdere M, Karaaslan B, Haliloğlu T, Varnalı Y. Baş ve boyunda pleomorfik adenom. Kulak Burun Bogaz Ihtis Derg 1997;4:93-7.
  • Krolls SO, Trodahl JN, Boyers RC. Salivary gland lesions in children. A survey of 430 cases. Cancer 1972;30:459-69.
  • Molina EJ, Mayer K, Khurana J, Grewal H. Pleomorphic adenoma of the submandibular gland. J Pediatr Surg 2008;43:1224-6.
  • Bentz BG, Hughes CA, Lüdemann JP, Maddalozzo J. Masses of the salivary gland region in children. Arch Otolaryngol Head Neck Surg 2000;126:1435-9.
  • Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 1986;8:177-84.
  • Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to his- tological types, site, age and sex distribution. J Pathol 1985;146:51-8.
  • Anadolu Y, Özgürsoy OB, Beton S. Çocukluk çağı parotis pleomorfik adenomları. KBB ve BBC Dergisi 2002;10:164-7.
  • Baker SR, Malone B. Salivary gland malignancies in children. Cancer 1985;55:1730-6.
  • Kakimoto N, Gamoh S, Tamaki J, Kishino M, Murakami S, Furukawa S. CT and MR images of pleo- morphic adenoma in major and minor salivary glands. Eur J Radiol 2009;69:464-72.
  • Handa U, Dhingra N, Chopra R, Mohan H. Pleomorphic adenoma: cytologic variations and potential diagnos- tic pitfalls. Diagn Cytopathol 2009;37:11-5.
  • Viguer JM, Vicandi B, Jiménez-Heffernan JA, López- Ferrer P, Limeres MA. Fine needle aspiration cytology of pleomorphic adenoma. An analysis of 212 cases. Acta Cytol 1997;41:786-94.
  • Alves FA, Perez DE, Almeida OP, Lopes MA, Kowalski LP. Pleomorphic adenoma of the submandibular gland: clinicopathological and immunohistochemical features of 60 cases in Brazil. Arch Otolaryngol Head Neck Surg 2002;128:1400-3.

Yedi yaşında bir çocukta submandibüler bez pleomorfik adenomu: Olgu sunumu

Yıl 2010, Cilt: 20 Sayı: 4, 210 - 213, 20.08.2010

Öz

Tükürük bezi neoplazmları pediatrik yaş grubunda nadir görülür. Submandibüler bezde pleomorfik adenom ise çok daha nadirdir. Bu yazıda, sağ submandibüler bölgede yavaş büyüyen kitlesi olan yedi yaşında kız olgu sunuldu. Sert, hareketli ve ağrısız kitle yaklaşık 2x3 cm boyutundaydı ve iki elle yapılan muayenede submandibüler bezden ayırt edilemiyordu. Kontrastlı manyetik rezonans görüntüleme ile submandibüler bez içerisinde sınırları belirgin, heterojen ve minimal lobulasyon gösteren kitle tespit edildi. İnce iğne aspirasyon biyopsisiyle pleomorfik adenom tanısı konuldu ve genel anestezi altında sağ submandibüler gland eksizyonu yapıldı. Kitlenin histopatolojik tanısı pleomorfik adenom idi ve görülen seyrek mito- tik aktivite malign transformasyon potansiyeline sahip olduğunu düşündürüyordu. Bir yıldır komp- likasyonsuz bir şekilde takibimizde olan bu hasta, bilgilerimize göre İngilizce literatürde bildirilmiş en genç olgudur

Kaynakça

  • Hockstein NG, Samadi DS, Gendron K, Carpentieri D, Wetmore RF. Pediatric submandibular triangle masses: a fifteen-year experience. Head Neck 2004;26:675-80.
  • Luna MA, Batsakis JG, el-Naggar AK. Salivary gland tumors in children. Ann Otol Rhinol Laryngol 1991; 100:869-71.
  • Guzzo M, Ferrari A, Marcon I, Collini P, Gandola L, Pizzi N, et al. Salivary gland neoplasms in children: the experience of the Istituto Nazionale Tumori of Milan. Pediatr Blood Cancer 2006;47:806-10.
  • Ellies M, Schaffranietz F, Arglebe C, Laskawi R. Tumors of the salivary glands in childhood and ado- lescence. J Oral Maxillofac Surg 2006;64:1049-58.
  • Ogata H, Ebihara S, Mukai K. Salivary gland neo- plasms in children. Jpn J Clin Oncol 1994;24:88-93.
  • Yıldırım G, Kuzdere M, Karaaslan B, Haliloğlu T, Varnalı Y. Baş ve boyunda pleomorfik adenom. Kulak Burun Bogaz Ihtis Derg 1997;4:93-7.
  • Krolls SO, Trodahl JN, Boyers RC. Salivary gland lesions in children. A survey of 430 cases. Cancer 1972;30:459-69.
  • Molina EJ, Mayer K, Khurana J, Grewal H. Pleomorphic adenoma of the submandibular gland. J Pediatr Surg 2008;43:1224-6.
  • Bentz BG, Hughes CA, Lüdemann JP, Maddalozzo J. Masses of the salivary gland region in children. Arch Otolaryngol Head Neck Surg 2000;126:1435-9.
  • Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg 1986;8:177-84.
  • Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to his- tological types, site, age and sex distribution. J Pathol 1985;146:51-8.
  • Anadolu Y, Özgürsoy OB, Beton S. Çocukluk çağı parotis pleomorfik adenomları. KBB ve BBC Dergisi 2002;10:164-7.
  • Baker SR, Malone B. Salivary gland malignancies in children. Cancer 1985;55:1730-6.
  • Kakimoto N, Gamoh S, Tamaki J, Kishino M, Murakami S, Furukawa S. CT and MR images of pleo- morphic adenoma in major and minor salivary glands. Eur J Radiol 2009;69:464-72.
  • Handa U, Dhingra N, Chopra R, Mohan H. Pleomorphic adenoma: cytologic variations and potential diagnos- tic pitfalls. Diagn Cytopathol 2009;37:11-5.
  • Viguer JM, Vicandi B, Jiménez-Heffernan JA, López- Ferrer P, Limeres MA. Fine needle aspiration cytology of pleomorphic adenoma. An analysis of 212 cases. Acta Cytol 1997;41:786-94.
  • Alves FA, Perez DE, Almeida OP, Lopes MA, Kowalski LP. Pleomorphic adenoma of the submandibular gland: clinicopathological and immunohistochemical features of 60 cases in Brazil. Arch Otolaryngol Head Neck Surg 2002;128:1400-3.
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Olgu Sunumu
Yazarlar

Serap Köybaşı Bu kişi benim

Ahmet Emre Süslü Bu kişi benim

Erkan Tezcan Bu kişi benim

Halil İbrahim Atasoy Bu kişi benim

Yusuf Özgür Biçer Bu kişi benim

Çetin Boran Bu kişi benim

Yayımlanma Tarihi 20 Ağustos 2010
Yayımlandığı Sayı Yıl 2010 Cilt: 20 Sayı: 4

Kaynak Göster

APA Köybaşı, S., Süslü, A. E., Tezcan, E., Atasoy, H. İ., vd. (2010). Submandibular gland pleomorphic adenoma in a seven-year-old child: a case report. The Turkish Journal of Ear Nose and Throat, 20(4), 210-213.
AMA Köybaşı S, Süslü AE, Tezcan E, Atasoy Hİ, Biçer YÖ, Boran Ç. Submandibular gland pleomorphic adenoma in a seven-year-old child: a case report. Tr-ENT. Ağustos 2010;20(4):210-213.
Chicago Köybaşı, Serap, Ahmet Emre Süslü, Erkan Tezcan, Halil İbrahim Atasoy, Yusuf Özgür Biçer, ve Çetin Boran. “Submandibular Gland Pleomorphic Adenoma in a Seven-Year-Old Child: A Case Report”. The Turkish Journal of Ear Nose and Throat 20, sy. 4 (Ağustos 2010): 210-13.
EndNote Köybaşı S, Süslü AE, Tezcan E, Atasoy Hİ, Biçer YÖ, Boran Ç (01 Ağustos 2010) Submandibular gland pleomorphic adenoma in a seven-year-old child: a case report. The Turkish Journal of Ear Nose and Throat 20 4 210–213.
IEEE S. Köybaşı, A. E. Süslü, E. Tezcan, H. İ. Atasoy, Y. Ö. Biçer, ve Ç. Boran, “Submandibular gland pleomorphic adenoma in a seven-year-old child: a case report”, Tr-ENT, c. 20, sy. 4, ss. 210–213, 2010.
ISNAD Köybaşı, Serap vd. “Submandibular Gland Pleomorphic Adenoma in a Seven-Year-Old Child: A Case Report”. The Turkish Journal of Ear Nose and Throat 20/4 (Ağustos 2010), 210-213.
JAMA Köybaşı S, Süslü AE, Tezcan E, Atasoy Hİ, Biçer YÖ, Boran Ç. Submandibular gland pleomorphic adenoma in a seven-year-old child: a case report. Tr-ENT. 2010;20:210–213.
MLA Köybaşı, Serap vd. “Submandibular Gland Pleomorphic Adenoma in a Seven-Year-Old Child: A Case Report”. The Turkish Journal of Ear Nose and Throat, c. 20, sy. 4, 2010, ss. 210-3.
Vancouver Köybaşı S, Süslü AE, Tezcan E, Atasoy Hİ, Biçer YÖ, Boran Ç. Submandibular gland pleomorphic adenoma in a seven-year-old child: a case report. Tr-ENT. 2010;20(4):210-3.