Evaluation of the effect of intranasal corticosteroid sprays on radiofrequency tissue ablation in the treatment of hypertrophied inferior turbinate

Yıl 2011, Cilt: 21 Sayı: 1, 10 - 14, 10.02.2011

Ceren Günel H. Sema Başak

Öz

Objectives: This study aims to evaluate the effect of combining the confidingly preferred modality of radiofrequency RF application with intranasal corticosteroid spray treatment on the efficacy of RF and on the number of sessions in patients with hypertrophy of inferior turbinate. Patients and Methods: Fifty patients 37 males, 13 females; mean age 42.9 years; range 15 to 74 years who admitted with the complaint of nasal obstruction and were detected to have hypertrophied inferior turbinate by nasal endoscopy were enrolled in the study. The patients were divided into two groups, each consisting of 25 patients. Before the treatment, the severity of nasal obstruction was evaluated and scored by a visual analogue scale VAS . Radiofrequency was applied to every patient. Control group received no medical treatment following RF application. Drug group received mometasone furoate nasal spray MFNS at a dose of 200 mcg once daily into both nasal passages for eight weeks following surgery. All patients were asked to return for a control visit at week eight after treatment. Radiofrequency application was repeated in patients who continued to have complaints of nasal blockage. At the end of treatment, patients were reevaluated and VAS scores were recorded. Results: The improvement in VAS scores following treatment was statistically significant in both groups p<0.05 . When the two groups were compared, there was no statistical difference between the two groups before treatment; however there was an improvement in the post-treatment corticostreoid group p<0.05 . The mean session number was calculated to be 1.16 in the control group and 1.08 in the corticosteroid treatment group. The difference between the two groups was not statistically significant p>0.05 . Conclusion: We recommend the use of intranasal corticosteroids with RF applications to increase the efficacy of radiofrequency.

Anahtar Kelimeler

Inferior concha hypertrophy, intranasal corticosteroids, radiofrequency

Alt konka hipertrofisinin tedavisinde uygulanan radyofrekans doku ablasyonuna intranazal kortikosteroid spreylerin etkisinin incelenmesi

Öz

Amaç: Bu çalışmada, alt konka hipertrofisi olan hastalarda güvenilerek tercih edilen bir yöntem olan radyofrekans RF uygulamasının, intranazal kortikosteroid sprey tedavisi ile kombine edilerek uygulanmasının RF’nin etkinliği ve seans sayısı üzerine etkisi araştırıldı.Hastalar ve Yöntemler: Burun tıkanıklığı yakınması ile başvuran ve nazal endoskopide alt konka hipertrofisi saptanan 50 hasta 37 erkek, 13 kadın; ort. yaş 42.9 yıl; dağılım 15-74 yıl çalışmaya alındı. Hastalar her bir grupta 25’er kişi olacak şekilde iki gruba ayrıldı. Tedavi öncesinde hastaların burun tıkanıklığı şiddeti görsel analog skala GAS ile değerlendirildi ve puanlandı. Tüm hastalara RF uygulandı. Kontrol grubuna RF uygulaması sonrası hiçbir medikal tedavi verilmedi. İlaç grubuna ise ameliyat sonrası sekiz hafta süreyle, günde bir kere, her iki burun pasajına 200 mcg uygulanacak şekilde mometazon furoat nazal sprey MFNS verildi. Tüm hastalar tedavi sonrası 8. haftada kontrole çağrıldı. Burun tıkanıklığı yakınması devam eden hastalara RF uygulaması tekrarlandı. Tedavi bitiminde tüm hastalar tekrar değerlendirildi ve GAS puanları kaydedildi.Bulgular: Tedavi sonrası GAS puanlarındaki iyileşme, her iki grupta da istatistiksel olarak anlamlıydı p

Anahtar Kelimeler

Alt konka hipertrofisi, intranazal kortikosteroidler, radyofrekans