The effect of topical mometasone furoate nasal spray on carriage of Staphylococcus aureus

Yıl 2014, Cilt: 24 Sayı: 1, 1 - 5, 15.02.2014

Cahit Polat Elif Bilge Uysal Salim Yüce İsmail Önder Uysal Sema Koç

Öz

Objectives: This study aims to examine the effect of topical mometasone furoate nasal spray on nasal Staphylococcus aureus S. aureus colonization in the treatment of allergic rhinitis. Patients and Methods: Between January 2012 and February 2013, 53 patients having perennial allergic rhinitis symptoms 37 females, 16 males and 53 healthy controls 36 females, 17 males were included in the study. Nasal cultures were obtained and evaluated before and after the treatment in allergic rhinitis patients who were admitted to the ear, nose and throat ENT outpatient clinic and receiving a mometasone furoate nasal spray treatment 200 mcg/day once a day for one-month. In healthy controls, nasal cultures were obtained and evaluated once. Results: In allergic rhinitis patients, five cultures were positive for S. aureus before the treatment while the number of cultures positive for S. aureus was six after the treatment. There was no significant difference in the pre-treatment and post-treatment S. aureus colonization between the patient group and controls p>0.05 . Conclusion: Mometasone furoate nasal spray used in the treatment of allergic rhinitis appears to be ineffective for nasal S. aureus colonization.

Anahtar Kelimeler

Allergic rhinitis, colonization, mometasone furoate, nasal spray, Staphylococcus aureus

Staphylococcus aureus taşıyıcılığı üzerinde topical mometazon furoat burun spreyinin etkisi

Öz

Amaç: Bu çalışmada alerjik rinit tedavisinde Staphylococcus aureus S. aureus kolonizasyonu üzerinde topical mometazon furoat burun spreyinin etkisi araştırıldı.Hastalar ve Yöntemler: Ocak 2012 - Şubat 2013 tarihleri arasında uzun yıllardır alerjik rinit semptomları olan 53 hasta 37 kadın, 16 erkek ve 53 sağlıklı kontrol 36 kadın, 17 erkek çalışmaya alındı. Kulak Burun Boğaz polikliniğine başvuran alerjik rinit hastalarından burun kültürleri alındı ve tedaviden önce ve bir ay boyunca günde bir kez mometazon furoat burun spreyi ile tedaviden sonra değerlendirildi. Sağlıklı kontrollerde burun kültürleri yalnızca bir kez alındı ve değerlendirildi.Bulgular: Alerjik rinit hastalarında tedaviden önce beş kültür S. aureus pozitif iken, tedaviden sonra altı kültür S. aureus pozitifti. Tedavi öncesi ve sonrası S. aureus kolonizasyonu açısından hasta grubu ve kontroller arasında anlamlı bir fark yoktu p>0.05 .Sonuç: Alerjik rinit tedavisinde kullanılan mometazon furoat burun spreyinin burun S. aureus kolonizasyonu açısından etkisiz olduğu görülmektedir

Anahtar Kelimeler

Alerjik rinit, kolonizasyon, mometazon furoat, burun spreyi, Staphylococcus aureus

Kaynakça

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