BibTex RIS Kaynak Göster

Mold hypersensitivity in children with frequent respiratory tract infection and prolonged cough attacks

Yıl 2014, Cilt: 24 Sayı: 4, 195 - 199, 25.09.2014

Öz

Objectives: This study aims to investigate pollen, mite and mold sensitivities among children with frequent respiratory tract infection living in damp apartments and to evaluate the effects of separated parents, education status, ethnicity, the presence of siblings, and their atopy status on the development of atopy. Patients and Methods: Between June 2012 and September 2013, 63 children 28 girls, 35 boys; mean age 80.2 years; range 24 to 97 years who were admitted to Acıbadem Bodrum Hospital with at least six respiratory tract infection per year with mold exposure and prolonged cough attacks and underwent skin prick test SPT were included. Skin prick test-positive patients were further divided into groups according to the upper respiratory tract URT or lower respiratory tract LRT involvement and were assessed for mold, mite and pollen sensitivities. Results: One-third of the patients were SPT positive. The parents of these patients had physician-diagnosed allergy p<0.05 . Most patients with mite sensitivity presented with URT and LRT findings p<0.05 . Pollen-sensitive patients had predominantly URT findings p<0.05 . All children with mold sensitivity presented with LRT findings p<0.05 . Conclusion: Atopic children may experience more frequent LRT symptoms when exposed to molds than non-atopic children. Mold exposure may also cause inflammation at LRT without causing immunoglobulin E-dependent sensitization.

Kaynakça

  • Richardson G, Eick S, Jones R. How is the indoor environment related to asthma?: literature review. J Adv Nurs 2005;52:328-39.
  • Mendell MJ, Mirer AG, Cheung K, Tong M, Douwes J. Respiratory and allergic health effects of dampness, mold, and dampness-related agents: a review of the epidemiologic evidence. Environ Health Perspect 2011;119:748-56.
  • Fisk WJ, Lei-Gomez Q, Mendell MJ. Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air 2007;17:284-96.
  • Ege MJ, Mayer M, Normand AC, Genuneit J, Cookson WO, Braun-Fahrländer C, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med 2011;364:701-9.
  • Engvall K, Norrby C, Norbäck D. Sick building syndrome in relation to building dampness in multi- family residential buildings in Stockholm. Int Arch Occup Environ Health 2001;74:270-8.
  • Douwes J, Pearce N. 'Invited commentary:is indoor mold exposure a risk factor for the asthma?' American Journal of Epidemiology 2003;158:203-6.
  • Hwang BF, Liu IP, Huang TP. Molds, parental atopy and pediatric incident asthma. Indoor Air 2011;21:472-8.
  • Hammer-Helmich L, Linneberg A, Thomsen SF, Glümer C. Association between parental socioeconomic position and prevalence of asthma, atopic eczema and hay fever in children. Scand J Public Health 2014;42:120-7.
  • Sahakian NM, Park JH, Cox-Ganser JM. Dampness and mold in the indoor environment: implications for asthma. Immunol Allergy Clin North Am 2008;28:485-505.
  • Institute of Medicine, Damp Indoor Spaces and Health. Washington, DC: The National Academies Press; 2004.
  • Jacob B, Ritz B, Gehring U, Koch A, Bischof W, Wichmann HE, et al. Indoor exposure to molds and allergic sensitization. Environ Health Perspect 2002;110:647-53.
  • Horner WE, Helbling A, Salvaggio JE, Lehrer SB. Fungal allergens. Clin Microbiol Rev 1995;8:161-79.
  • ACOEM Council on Scientific Affairs. American College of Environmental and Occupational Medicine position statement. Adverse health effects associated with molds in the indoor environment. Elk Grove Village (III): ACOEM; 2002.
  • Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Ublagger E, et al. Bacterial and fungal agents in house dust and wheeze in children: the Parsifal study. Clin Exp Allergy 2005;35:1272-8.
  • Salvaggio JE. Use and misuse of biomarker tests in “environmental conditions”. J Allergy Clin Immunol 1994;94:380-4.
  • Cohen B. McCammon CS. Air sampling instruments. 9th ed. Cincinnati (OH): AGCIH Worldwide; 2001.
  • Macher J, editor. Bioaerosols: assessment and control. 2nd ed. Cincinnati (OH): AGCIH Worldwide; 1999.
  • Bush RK, Portnoy JM, Saxon A, Terr AI, Wood RA. The medical effects of mold exposure. J Allergy Clin Immunol 2006;117:326-33.
  • Kilpeläinen M, Terho EO, Helenius H, Koskenvuo M. Home dampness, current allergic diseases, and respiratory infections among young adults. Thorax 2001;56:462-7.

Sık solunum yolu enfeksiyonu ve uzamış öksürük atakları olan çocuklarda küf duyarlılığı

Yıl 2014, Cilt: 24 Sayı: 4, 195 - 199, 25.09.2014

Öz

Amaç: Bu çalışmada sık solunum yolu enfeksiyonu geçiren, rutubetli evlerde yaşayan çocuklarda polen, akar ve küf duyarlılıkları incelendi ve ebeveynlerin ayrılığı, eğitim durumu, etnik köken, kardeş sahibi olma ve kardeşlerin atopi durumunun atopi gelişimi üzerindeki etkileri değerlendirildi.Hastalar ve Yöntemler: Haziran 2012 - Eylül 2013 tarihleri arasında Acıbadem Bodrum hastanesine küf maruziyeti ile yılda en az altı solunum yolu enfeksiyonu SYE ve uzamış öksürük atakları ile başvuran ve deri prick testi yapılan 63 çocuk 28 kız, 35 erkek; ort. yaş 80.2 ay; dağılım 24-97 ay çalışmaya dahil edildi. Deri prick testi pozitif DTP olan hastalar alt solunum yolu ASY veya üst solunum yolu ÜSY tutulumlarına göre gruplandırıldı ve küf, akar ve polen duyarlılık durumları incelendi.Bulgular: Hastaların üçte birinde DTP saptandı. Bu hastaların ebeveynlerinde yüksek oranda doktor tanılı alerji varlığı izlendi p

Kaynakça

  • Richardson G, Eick S, Jones R. How is the indoor environment related to asthma?: literature review. J Adv Nurs 2005;52:328-39.
  • Mendell MJ, Mirer AG, Cheung K, Tong M, Douwes J. Respiratory and allergic health effects of dampness, mold, and dampness-related agents: a review of the epidemiologic evidence. Environ Health Perspect 2011;119:748-56.
  • Fisk WJ, Lei-Gomez Q, Mendell MJ. Meta-analyses of the associations of respiratory health effects with dampness and mold in homes. Indoor Air 2007;17:284-96.
  • Ege MJ, Mayer M, Normand AC, Genuneit J, Cookson WO, Braun-Fahrländer C, et al. Exposure to environmental microorganisms and childhood asthma. N Engl J Med 2011;364:701-9.
  • Engvall K, Norrby C, Norbäck D. Sick building syndrome in relation to building dampness in multi- family residential buildings in Stockholm. Int Arch Occup Environ Health 2001;74:270-8.
  • Douwes J, Pearce N. 'Invited commentary:is indoor mold exposure a risk factor for the asthma?' American Journal of Epidemiology 2003;158:203-6.
  • Hwang BF, Liu IP, Huang TP. Molds, parental atopy and pediatric incident asthma. Indoor Air 2011;21:472-8.
  • Hammer-Helmich L, Linneberg A, Thomsen SF, Glümer C. Association between parental socioeconomic position and prevalence of asthma, atopic eczema and hay fever in children. Scand J Public Health 2014;42:120-7.
  • Sahakian NM, Park JH, Cox-Ganser JM. Dampness and mold in the indoor environment: implications for asthma. Immunol Allergy Clin North Am 2008;28:485-505.
  • Institute of Medicine, Damp Indoor Spaces and Health. Washington, DC: The National Academies Press; 2004.
  • Jacob B, Ritz B, Gehring U, Koch A, Bischof W, Wichmann HE, et al. Indoor exposure to molds and allergic sensitization. Environ Health Perspect 2002;110:647-53.
  • Horner WE, Helbling A, Salvaggio JE, Lehrer SB. Fungal allergens. Clin Microbiol Rev 1995;8:161-79.
  • ACOEM Council on Scientific Affairs. American College of Environmental and Occupational Medicine position statement. Adverse health effects associated with molds in the indoor environment. Elk Grove Village (III): ACOEM; 2002.
  • Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Ublagger E, et al. Bacterial and fungal agents in house dust and wheeze in children: the Parsifal study. Clin Exp Allergy 2005;35:1272-8.
  • Salvaggio JE. Use and misuse of biomarker tests in “environmental conditions”. J Allergy Clin Immunol 1994;94:380-4.
  • Cohen B. McCammon CS. Air sampling instruments. 9th ed. Cincinnati (OH): AGCIH Worldwide; 2001.
  • Macher J, editor. Bioaerosols: assessment and control. 2nd ed. Cincinnati (OH): AGCIH Worldwide; 1999.
  • Bush RK, Portnoy JM, Saxon A, Terr AI, Wood RA. The medical effects of mold exposure. J Allergy Clin Immunol 2006;117:326-33.
  • Kilpeläinen M, Terho EO, Helenius H, Koskenvuo M. Home dampness, current allergic diseases, and respiratory infections among young adults. Thorax 2001;56:462-7.
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makalesi
Yazarlar

Özlem Naciye Şahin Bu kişi benim

Pınar Yaprak Bu kişi benim

Figen Gülen Bu kişi benim

Alp Korkut Perçin Bu kişi benim

Yayımlanma Tarihi 25 Eylül 2014
Yayımlandığı Sayı Yıl 2014 Cilt: 24 Sayı: 4

Kaynak Göster

APA Şahin, Ö. N., Yaprak, P., Gülen, F., Perçin, A. K. (2014). Sık solunum yolu enfeksiyonu ve uzamış öksürük atakları olan çocuklarda küf duyarlılığı. The Turkish Journal of Ear Nose and Throat, 24(4), 195-199.
AMA Şahin ÖN, Yaprak P, Gülen F, Perçin AK. Sık solunum yolu enfeksiyonu ve uzamış öksürük atakları olan çocuklarda küf duyarlılığı. Tr-ENT. Eylül 2014;24(4):195-199.
Chicago Şahin, Özlem Naciye, Pınar Yaprak, Figen Gülen, ve Alp Korkut Perçin. “Sık Solunum Yolu Enfeksiyonu Ve uzamış öksürük Atakları Olan çocuklarda küf duyarlılığı”. The Turkish Journal of Ear Nose and Throat 24, sy. 4 (Eylül 2014): 195-99.
EndNote Şahin ÖN, Yaprak P, Gülen F, Perçin AK (01 Eylül 2014) Sık solunum yolu enfeksiyonu ve uzamış öksürük atakları olan çocuklarda küf duyarlılığı. The Turkish Journal of Ear Nose and Throat 24 4 195–199.
IEEE Ö. N. Şahin, P. Yaprak, F. Gülen, ve A. K. Perçin, “Sık solunum yolu enfeksiyonu ve uzamış öksürük atakları olan çocuklarda küf duyarlılığı”, Tr-ENT, c. 24, sy. 4, ss. 195–199, 2014.
ISNAD Şahin, Özlem Naciye vd. “Sık Solunum Yolu Enfeksiyonu Ve uzamış öksürük Atakları Olan çocuklarda küf duyarlılığı”. The Turkish Journal of Ear Nose and Throat 24/4 (Eylül 2014), 195-199.
JAMA Şahin ÖN, Yaprak P, Gülen F, Perçin AK. Sık solunum yolu enfeksiyonu ve uzamış öksürük atakları olan çocuklarda küf duyarlılığı. Tr-ENT. 2014;24:195–199.
MLA Şahin, Özlem Naciye vd. “Sık Solunum Yolu Enfeksiyonu Ve uzamış öksürük Atakları Olan çocuklarda küf duyarlılığı”. The Turkish Journal of Ear Nose and Throat, c. 24, sy. 4, 2014, ss. 195-9.
Vancouver Şahin ÖN, Yaprak P, Gülen F, Perçin AK. Sık solunum yolu enfeksiyonu ve uzamış öksürük atakları olan çocuklarda küf duyarlılığı. Tr-ENT. 2014;24(4):195-9.