Sinonasal teratocarcinosarcoma

Yıl 2014, Cilt: 24 Sayı: 4, 237 - 241, 25.09.2014

Kadri İla Mete İşeri Selvet Erdoğan Gürkan Keskin Kenan Koç Bahar Müezzinoğlu

Öz

Sinonasal teratocarcinosarcoma is an extremely rare malignant neoplasm presenting with the characteristics of a malignant teratoma and carcinosarcoma. The most common sites of origin of teratocarcinosarcomas are the nasal cavity and paranasal sinuses. The clinical presentation is usually with nasal obstruction and episodes of epistaxis. Teratocarcinosarcomas are aggressive and rapidly growing tumors with a poor prognosis. The incidence of sinonasal teratocarcinomas is higher in men than women. Treatment is primarily surgery, followed by radiotherapy. In this article, we report a 46-year-old male case of sinonasal teratocarcinosarcoma who was admitted with complaints of pain and swelling around the right eye and treated surgically followed by radiotherapy.

Anahtar Kelimeler

Sinonasal, surgery, teratocarcinosarcoma

Sinonazal teratokarsinosarkom

Öz

Sinonazal teratokarsinosarkom, karsinosarkom ve malign teratom özelliklerini birlikte taşıyan oldukça nadir bir tümördür. Teratokarsinosarkomlar en sık burun boşluğu ve paranazal sinüslerden kaynaklanır. Klinik tablo çoğunluk- la burun tıkanıklığı ve burun kanaması atakları ile kendini gösterir. Teratokarsinosarkom prognozu kötü, agresif ve hızlı ilerleyen bir tümördür. Bu tümörün erkeklerde görülme sıklığı kadınlara kıyasla daha yüksektir. Tedavisi primer cerrahiyi takiben radyoterapidir. Bu makalede, sağ göz çevresinde şişlik ve ağrı yakınması ile başvuran ve cerrahiyi takiben radyoterapi ile tedavi edilen 46 yaşında erkek bir sinonazal teratokarsinom olgusu sunuldu

Anahtar Kelimeler

Sinonazal, cerrahi, teratokarsinosarkom

Kaynakça

• Su YY, Friedman M, Huang CC, Wilson M, Lin HC. Sinonasal teratocarcinosarcoma. Am J Otolaryngol 2010;31:300-3.
• Smith SL, Hessel AC, Luna MA, Malpica A, Rosenthal DI, El-Naggar AK. Sinonasal teratocarcinosarcoma of the head and neck: a report of 10 patients treated at a single institution and comparison with reported series. Arch Otolaryngol Head Neck Surg 2008;134:592-5.
• Yang S, Sun R, Liang J, Zhou Z, Zhou J, Rui J. Sinonasal teratocarcinosarcoma: a clinical and pathological analysis. Int J Surg Pathol 2013;21:37-43.
• Endo H, Hirose T, Kuwamura KI, Sano T. Case report: Sinonasal teratocarcinosarcoma. Pathol Int 2001;51:107-12.
• Tchoyoson Lim CC, Thiagarajan A, Sim CS, Khoo ML, Shakespeare TP, Ng I. Craniospinal dissemination in teratocarcinosarcoma. J Neurosurg 2008;109:321-4.
• Agrawal N, Chintagumpala M, Hicks J, Eldin K, Paulino AC. Sinonasal teratocarcinosarcoma in an adolescent male. J Pediatr Hematol Oncol 2012;34:e304-7.
• Chao KK, Eng TY, Barnes J, Dahiya R. Sinonasal teratocarcinosarcoma. Am J Clin Oncol 2004;27:29-32.
• Shorter C, Nourbakhsh A, Dean M, Thomas-Ogunniyi J, Lian TS, Guthikonda B. Intracerebral metastasis of a sinonasal teratocarcinosarcoma: a case report. Skull Base 2010;20:393-6.
• Tokunaga T, Sunaga H, Kimura Y, Tsuda G, Fujieda S. A case of sinonasal teratocarcinosarcoma treated with surgery and post-operative intensity- modulated radiotherapy (IMRT). Auris Nasus Larynx 2012;39:641-5.
• Carrizo F, Pineda-Daboin K, Neto AG, Luna MA. Pharyngeal teratocarcinosarcoma: review of the literature and report of two cases. Ann Diagn Pathol 2006;10:339-42.
• Takasaki K, Sakihama N, Takahashi H. A case with sinonasal teratocarcinosarcoma in the nasal cavity and ethmoid sinus. Eur Arch Otorhinolaryngol 2006;263:586-91.