BibTex RIS Kaynak Göster

Histopathological analysis of tonsillectomy specimens: a report from Southeastern Anatolia

Yıl 2014, Cilt: 24 Sayı: 5, 254 - 258, 15.10.2014

Öz

Objectives: This study aims to evaluate the necessity of routine histopathological analyses of tonsillectomy specimens. Patients and Methods: A retrospective review for 2,004 patients 1,048 males, 956 females; mean age 12.2 years; range 2 to 60 years who underwent tonsillectomy between January 2009 and May 2013 was carried out at the Diyarbakır Training and Research Hospital, Turkey. Tonsillectomy specimens were fixed with formalin, and stained with hematoxylin and eosin before being sectioned and examined via light microscope. Chronic inflammation and lymphoid hyperplasia were considered non-significant pathological findings. Other pathological diagnoses including infectious processes, and benign and malignant neoplasms were regarded as significant pathological findings. Results: Non-significant pathological findings -chronic inflammation, lymphoid hyperplasia or both- were observed in 1,972 patients. Significant pathological findings -epidermal cyst, mucocele, squamous papilloma, granuloma and squamous cell carcinoma- were observed in 32 patients. One patient was diagnosed with squamous cell carcinoma, and another had granulomatous disease diagnosed as tuberculosis. Conclusion: Histopathological examination is only necessary for patients with preoperative risk factors. Gross examination may be a good alternative since it is cost effective and not time consuming.

Kaynakça

  • Dohar JE, Bonilla JA. Processing of adenoid and tonsil specimens in children: A national survey of standard practices and a five-year review of the experience at the Children's Hospital of Pittsburgh. Otolaryngol Head Neck Surg 1996;115:94-7.
  • Garavello W, Romagnoli M, Sordo L, Spreafico R, Gaini RM. Incidence of unexpected malignancies in routine tonsillectomy specimens in children, Laryngoscope 2004;114:1103-5.
  • Netser JC, Robinson RA, Smith RJ, Raab SS. Value based pathology: A cost analysis of the examination of routine and nonroutine tonsil and adenoid specimens, Am J Clin Pathol 1997;108:158-65.
  • Strong EB, Rubinstein B, Senders CW. Pathologic analysis of routine tonsillectomy and adenoidectomy specimens. Otolaryngol Head Neck Surgery 2001;125:473-7.
  • Alvi A, Vartanian AJ. Microscopic examination of routine tonsillectomy specimens: is it necessary? Otolaryngol Head Neck Surg 1998;119:361-3.
  • Ikram M, Khan MA, Ahmed M, Siddiqui T, Mian MY. The histopathology of routine tonsillectomy specimens: results of a study and review of literature. Ear Nose Throat J 2000;79:880-2.
  • Reiter ER, Randolph GW, Pilch BZ. Microscopic detection of occult malignancy in the adult tonsil. Otolaryngol Head Neck Surg 1999;120:190-4.
  • Felippe F, Gomes GA, de Souza BP, Cardoso GA, Tomita S. Evaluation of the utility of histopathologic exam as a routine in tonsillectomies. Braz J Otorhinolaryngol 2006;72:252-5.
  • Daneshbod K, Bhutta R, Sodagar R, Pathology of tonsils and adenoids: a study of 15,120 cases, Ear Nose Throat J 1980;59:53-4.
  • Beaty MM, Funk GF, Karnell LH, Graham SM, McCulloch TM, Hoffman HT, et al. Risk factors for malignancy in adult tonsils. Head Neck 1998; 20:399-403.
  • Younis RT, Hesse SV, Anand VK. Evaluation of the utility and cost-effectiveness of obtaining histopathologic diagnosis on all routine tonsillectomy specimens. Laryngoscope 2001;111:2166-9.
  • Oluwasanmi AF, Wood SJ, Baldwin DL, Sipaul F. Malignancy in asymmetrical but otherwise normal palatine tonsils. Ear Nose Throat J 2006;85:661-3.
  • Smitheringale A. Lymphomas presenting in Waldeyer’s ring. J Otolaryngol 2000;29:183-5.
  • Williams MD, Brown HM. The adequacy of gross pathological examination of routine tonsils and adenoids in patients 21 years old and younger. Hum Pathol 2003;34:1053-7.
  • Erdag TK, Ecevit MC, Guneri EA, Dogan E, Ikiz AO, Sutay S. Pathologic evaluation of routine tonsillectomy and adenoidectomy specimens in the pediatric population: Is it really necessary? Int J Pediatr Otorhinolaryngol 2005;69:1321-5.
  • Thorne MC. Is routine analysis of pediatric tonsillectomy specimens worth the money? Ear Nose Throat J 2012;91:186.

Tonsillektomi numunelerinin histopatolojik analizi: Güneydoğu Anadolu’dan bir rapor

Yıl 2014, Cilt: 24 Sayı: 5, 254 - 258, 15.10.2014

Öz

Amaç: Bu çalışmada tonsillektomi numunelerinin rutin histopatolojik analizlerinin gerekliliği değerlendirildi.Hastalar ve Yöntemler: Diyarbakır Eğitim ve Araştırma Hastanesi’nde Ocak 2009 ve Mayıs 2013 tarihleri arasında tonsillektomi geçiren 2.004 hasta 1.048 erkek, 956 kadın; ort. yaş 12.2 yıl; dağılım 2-60 yıl için retrospektif bir inceleme yapıldı. Tonsillektomi numuneleri kesitlere ayrılıp ışık mikroskobu ile incelenmeden önce formalin ile tespit edildi ve hematoksilen ve eozin ile boyandı. Kronik enflamasyon ve lenfoid hiperplazi anlamlı olmayan patolojik bulgular olarak kabul edildi. Enfeksiyöz süreçler, iyi huylu ve kötü huylu neoplazmlar gibi diğer patolojik tanılar anlamlı patolojik bulgular olarak dikkate alındı.Bulgular: Kronik enflamasyonu, lenfoid hiperplaziyi veya her ikisini içeren anlamlı olmayan patolojik bulgular 1.972 hastada gözlemlendi. Epidermal kist, mukosel, skuamöz papillom, granülom ve skuamöz hücreli karsinomu içeren anlamlı patolojik bulgular 32 hastada gözlemlendi. Bir hastaya skuamöz hücreli karsinom tanısı konuldu, bir diğerinde tüberküloz tanısı konulan granülomatöz hastalık vardı.Sonuç: Histopatolojik inceleme sadece ameliyat öncesi risk faktörleri olan hastalar için gereklidir. Maliyet etkin olup zaman alıcı olmayan makroskopik inceleme iyi bir seçenek olabilir

Kaynakça

  • Dohar JE, Bonilla JA. Processing of adenoid and tonsil specimens in children: A national survey of standard practices and a five-year review of the experience at the Children's Hospital of Pittsburgh. Otolaryngol Head Neck Surg 1996;115:94-7.
  • Garavello W, Romagnoli M, Sordo L, Spreafico R, Gaini RM. Incidence of unexpected malignancies in routine tonsillectomy specimens in children, Laryngoscope 2004;114:1103-5.
  • Netser JC, Robinson RA, Smith RJ, Raab SS. Value based pathology: A cost analysis of the examination of routine and nonroutine tonsil and adenoid specimens, Am J Clin Pathol 1997;108:158-65.
  • Strong EB, Rubinstein B, Senders CW. Pathologic analysis of routine tonsillectomy and adenoidectomy specimens. Otolaryngol Head Neck Surgery 2001;125:473-7.
  • Alvi A, Vartanian AJ. Microscopic examination of routine tonsillectomy specimens: is it necessary? Otolaryngol Head Neck Surg 1998;119:361-3.
  • Ikram M, Khan MA, Ahmed M, Siddiqui T, Mian MY. The histopathology of routine tonsillectomy specimens: results of a study and review of literature. Ear Nose Throat J 2000;79:880-2.
  • Reiter ER, Randolph GW, Pilch BZ. Microscopic detection of occult malignancy in the adult tonsil. Otolaryngol Head Neck Surg 1999;120:190-4.
  • Felippe F, Gomes GA, de Souza BP, Cardoso GA, Tomita S. Evaluation of the utility of histopathologic exam as a routine in tonsillectomies. Braz J Otorhinolaryngol 2006;72:252-5.
  • Daneshbod K, Bhutta R, Sodagar R, Pathology of tonsils and adenoids: a study of 15,120 cases, Ear Nose Throat J 1980;59:53-4.
  • Beaty MM, Funk GF, Karnell LH, Graham SM, McCulloch TM, Hoffman HT, et al. Risk factors for malignancy in adult tonsils. Head Neck 1998; 20:399-403.
  • Younis RT, Hesse SV, Anand VK. Evaluation of the utility and cost-effectiveness of obtaining histopathologic diagnosis on all routine tonsillectomy specimens. Laryngoscope 2001;111:2166-9.
  • Oluwasanmi AF, Wood SJ, Baldwin DL, Sipaul F. Malignancy in asymmetrical but otherwise normal palatine tonsils. Ear Nose Throat J 2006;85:661-3.
  • Smitheringale A. Lymphomas presenting in Waldeyer’s ring. J Otolaryngol 2000;29:183-5.
  • Williams MD, Brown HM. The adequacy of gross pathological examination of routine tonsils and adenoids in patients 21 years old and younger. Hum Pathol 2003;34:1053-7.
  • Erdag TK, Ecevit MC, Guneri EA, Dogan E, Ikiz AO, Sutay S. Pathologic evaluation of routine tonsillectomy and adenoidectomy specimens in the pediatric population: Is it really necessary? Int J Pediatr Otorhinolaryngol 2005;69:1321-5.
  • Thorne MC. Is routine analysis of pediatric tonsillectomy specimens worth the money? Ear Nose Throat J 2012;91:186.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Araştırma Makalesi
Yazarlar

İsa Özbay Bu kişi benim

Metehan Gençoğlu Bu kişi benim

Hasan Hüseyin Balıkçı Bu kişi benim

Cüneyt Kucur Bu kişi benim

Fatih Oğhan Bu kişi benim

Yayımlanma Tarihi 15 Ekim 2014
Yayımlandığı Sayı Yıl 2014 Cilt: 24 Sayı: 5

Kaynak Göster

APA Özbay, İ., Gençoğlu, M., Balıkçı, H. H., Kucur, C., vd. (2014). Histopathological analysis of tonsillectomy specimens: a report from Southeastern Anatolia. The Turkish Journal of Ear Nose and Throat, 24(5), 254-258.
AMA Özbay İ, Gençoğlu M, Balıkçı HH, Kucur C, Oğhan F. Histopathological analysis of tonsillectomy specimens: a report from Southeastern Anatolia. Tr-ENT. Ekim 2014;24(5):254-258.
Chicago Özbay, İsa, Metehan Gençoğlu, Hasan Hüseyin Balıkçı, Cüneyt Kucur, ve Fatih Oğhan. “Histopathological Analysis of Tonsillectomy Specimens: A Report from Southeastern Anatolia”. The Turkish Journal of Ear Nose and Throat 24, sy. 5 (Ekim 2014): 254-58.
EndNote Özbay İ, Gençoğlu M, Balıkçı HH, Kucur C, Oğhan F (01 Ekim 2014) Histopathological analysis of tonsillectomy specimens: a report from Southeastern Anatolia. The Turkish Journal of Ear Nose and Throat 24 5 254–258.
IEEE İ. Özbay, M. Gençoğlu, H. H. Balıkçı, C. Kucur, ve F. Oğhan, “Histopathological analysis of tonsillectomy specimens: a report from Southeastern Anatolia”, Tr-ENT, c. 24, sy. 5, ss. 254–258, 2014.
ISNAD Özbay, İsa vd. “Histopathological Analysis of Tonsillectomy Specimens: A Report from Southeastern Anatolia”. The Turkish Journal of Ear Nose and Throat 24/5 (Ekim 2014), 254-258.
JAMA Özbay İ, Gençoğlu M, Balıkçı HH, Kucur C, Oğhan F. Histopathological analysis of tonsillectomy specimens: a report from Southeastern Anatolia. Tr-ENT. 2014;24:254–258.
MLA Özbay, İsa vd. “Histopathological Analysis of Tonsillectomy Specimens: A Report from Southeastern Anatolia”. The Turkish Journal of Ear Nose and Throat, c. 24, sy. 5, 2014, ss. 254-8.
Vancouver Özbay İ, Gençoğlu M, Balıkçı HH, Kucur C, Oğhan F. Histopathological analysis of tonsillectomy specimens: a report from Southeastern Anatolia. Tr-ENT. 2014;24(5):254-8.