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Clinical features of deep neck infection: analysis of 77 patients

Yıl 2015, Cilt: 25 Sayı: 2, 102 - 108, 20.05.2015

Öz

Objectives: This retrospective study aims to detect the prognostic factors which affect the duration of hospital stay and evaluate the complications which develop in patients with deep neck infection. Patients and Methods: The study included 77 patients 40 males, 37 females; mean age 42.4±20.1 years; range 11 to 88 years treated with a diagnosis of deep neck infection in our clinic between November 2006 and November 2012. Patients’ demographic and clinical features were analyzed to detect their associations with development of complications and hospitalization time. Results: Odontogenic origin and submandibular localization were the most frequently observed clinical appearance. Of eight patients 10.4% who developed serious complications, two 2.6% died. Age, comorbidity, presence of anemia alone, Ludwig's angina and retropharyngeal involvement were associated with increased rate of complications p<0.05 ; while sex, antibiotic usage prior to admittance and primary location of infection were not related p>0.05 . Submandibular localization and absence of leucopenia reduced the risk of complications p<0.05 . The mean duration of hospital stay was 12.9±8.7 days range 2-59 days . Age, presence of comorbidity and development of complications extended the hospitalization period p<0.05 . Conclusion: In spite of the improvements in diagnosis and treatment, deep neck infection may be an important cause of mortality if complications develop. Comorbid anemia, Ludwig's angina and retropharyngeal involvement were identified as the strongest predictors in terms of development of complications. Duration of hospital stay extended in patients who developed complications.

Kaynakça

  • Larawin V, Naipao J, Dubey SP. Head and neck space infections. Otolaryngol Head Neck Surg 2006;135:889-93.
  • Vieira F, Allen SM, Stocks RM, Thompson JW. Deep neck infection. Otolaryngol Clin North Am 2008;41:459-83.
  • Henrich DE, Smith TL, Shockley WW. Fatal craniocervical necrotizing fasciitis in an immunocompetent patient: a case report and literature review. Head Neck 1995;17:351-7.
  • Ridder GJ, Maier W, Kinzer S, Teszler CB, Boedeker CC, Pfeiffer J. Descending necrotizing mediastinitis: contemporary trends in etiology, diagnosis, management, and outcome. Ann Surg 2010;251:528-34.
  • Hsu RF, Wu PY, Ho CK. Transcervical drainage for descending necrotizing mediastinitis may be sufficient. Otolaryngol Head Neck Surg 2011;145:742-7.
  • Daramola OO, Flanagan CE, Maisel RH, Odland RM. Diagnosis and treatment of deep neck space abscesses. Otolaryngol Head Neck Surg 2009;141:123-30.
  • Kinzer S, Pfeiffer J, Becker S, Ridder GJ. Severe deep neck space infections and mediastinitis of odontogenic origin: clinical relevance and implications for diagnosis and treatment. Acta Otolaryngol 2009;129:62-70.
  • Suehara AB, Gonçalves AJ, Alcadipani FA, Kavabata NK, Menezes MB. Deep neck infection: analysis of 80 cases. Braz J Otorhinolaryngol 2008;74:253-9.
  • Maroldi R, Farina D, Ravanelli M, Lombardi D, Nicolai P. Emergency imaging assessment of deep neck space infections. Semin Ultrasound CT MR 2012;33:432-42.
  • Yang SW, Lee MH, Lee YS, Huang SH, Chen TA, Fang TJ. Analysis of life-threatening complications of deep neck abscess and the impact of empiric antibiotics. ORL J Otorhinolaryngol Relat Spec 2008;70:249-56.
  • Brook I. Microbiology and management of peritonsillar, retropharyngeal, and parapharyngeal abscesses. J Oral Maxillofac Surg 2004;62:1545-50.
  • Boyanova L, Kolarov R, Gergova G, Deliverska E, Madjarov J, Marinov M, et al. Anaerobic bacteria in 118 patients with deep-space head and neck infections from the University Hospital of Maxillofacial Surgery, Sofia, Bulgaria. J Med Microbiol 2006;55:1285-9.
  • Wang CP, Ko JY, Lou PJ. Deep neck infection as the main initial presentation of primary head and neck cancer. J Laryngol Otol 2006;120:305-9.
  • Baba S, Baba M, Hagisawa M, Kimura M, Nakashima M, Nakahara H. A case of nasal natural killer/T lymphoma revealed by repeated deep neck abscess. Am J Otolaryngol 2009;30:269-72.
  • Santos Gorjón P, Blanco Pérez P, Morales Martín AC, Del Pozo de Dios JC, Estévez Alonso S, Calle de la Cabanillas MI. Deep neck infection. Review of 286 cases. Acta Otorrinolaringol Esp 2012;63:31-41.
  • Sarna T, Sengupta T, Miloro M, Kolokythas A. Cervical necrotizing fasciitis with descending mediastinitis: literature review and case report. J Oral Maxillofac Surg 2012;70:1342-50.

Derin boyun enfeksiyonunun klinik özellikleri: 77 hastanın analizi

Yıl 2015, Cilt: 25 Sayı: 2, 102 - 108, 20.05.2015

Öz

Amaç: Bu retrospektif çalışmada derin boyun enfeksiyonlu hastalarda hastanede kalım süresini etkileyen prognostik faktörler belirlendi ve bu hastalarda ortaya çıkan komplikasyonlar değerlendirildi.Hastalar ve Yöntemler: Kasım 2006 - Kasım 2012 tarihleri arasında derin boyun enfeksiyonu tanısıyla kliniğimizde tedavi gören 77 hasta 40 erkek, 37 kadın; ort. yaş 42.4±20.1 yıl; dağılım 11-88 yıl çalışmaya alındı. Hastaların demografik ve klinik özellikleri komplikasyon gelişimi ve hastanede kalım süreleri ile ilişkilerinin belirlenmesi için incelendi.Bulgular: Odontojenik orijin ve submandibüler yerleşim en sık görülen klinik görünümdü. Ciddi komplikasyon gelişen sekiz hastadan %10.4 ikisi %2.6 kaybedildi. Yaş, eşlik eden hastalık, yalnız anemi varlığı, Ludwig anjini ve retrofarengeal tutulum komplikasyon oranlarında artışla ilişkili iken p0.05 . Submandibüler yerleşim ve lökopeni yokluğu komplikasyon riskini azalttı p

Kaynakça

  • Larawin V, Naipao J, Dubey SP. Head and neck space infections. Otolaryngol Head Neck Surg 2006;135:889-93.
  • Vieira F, Allen SM, Stocks RM, Thompson JW. Deep neck infection. Otolaryngol Clin North Am 2008;41:459-83.
  • Henrich DE, Smith TL, Shockley WW. Fatal craniocervical necrotizing fasciitis in an immunocompetent patient: a case report and literature review. Head Neck 1995;17:351-7.
  • Ridder GJ, Maier W, Kinzer S, Teszler CB, Boedeker CC, Pfeiffer J. Descending necrotizing mediastinitis: contemporary trends in etiology, diagnosis, management, and outcome. Ann Surg 2010;251:528-34.
  • Hsu RF, Wu PY, Ho CK. Transcervical drainage for descending necrotizing mediastinitis may be sufficient. Otolaryngol Head Neck Surg 2011;145:742-7.
  • Daramola OO, Flanagan CE, Maisel RH, Odland RM. Diagnosis and treatment of deep neck space abscesses. Otolaryngol Head Neck Surg 2009;141:123-30.
  • Kinzer S, Pfeiffer J, Becker S, Ridder GJ. Severe deep neck space infections and mediastinitis of odontogenic origin: clinical relevance and implications for diagnosis and treatment. Acta Otolaryngol 2009;129:62-70.
  • Suehara AB, Gonçalves AJ, Alcadipani FA, Kavabata NK, Menezes MB. Deep neck infection: analysis of 80 cases. Braz J Otorhinolaryngol 2008;74:253-9.
  • Maroldi R, Farina D, Ravanelli M, Lombardi D, Nicolai P. Emergency imaging assessment of deep neck space infections. Semin Ultrasound CT MR 2012;33:432-42.
  • Yang SW, Lee MH, Lee YS, Huang SH, Chen TA, Fang TJ. Analysis of life-threatening complications of deep neck abscess and the impact of empiric antibiotics. ORL J Otorhinolaryngol Relat Spec 2008;70:249-56.
  • Brook I. Microbiology and management of peritonsillar, retropharyngeal, and parapharyngeal abscesses. J Oral Maxillofac Surg 2004;62:1545-50.
  • Boyanova L, Kolarov R, Gergova G, Deliverska E, Madjarov J, Marinov M, et al. Anaerobic bacteria in 118 patients with deep-space head and neck infections from the University Hospital of Maxillofacial Surgery, Sofia, Bulgaria. J Med Microbiol 2006;55:1285-9.
  • Wang CP, Ko JY, Lou PJ. Deep neck infection as the main initial presentation of primary head and neck cancer. J Laryngol Otol 2006;120:305-9.
  • Baba S, Baba M, Hagisawa M, Kimura M, Nakashima M, Nakahara H. A case of nasal natural killer/T lymphoma revealed by repeated deep neck abscess. Am J Otolaryngol 2009;30:269-72.
  • Santos Gorjón P, Blanco Pérez P, Morales Martín AC, Del Pozo de Dios JC, Estévez Alonso S, Calle de la Cabanillas MI. Deep neck infection. Review of 286 cases. Acta Otorrinolaringol Esp 2012;63:31-41.
  • Sarna T, Sengupta T, Miloro M, Kolokythas A. Cervical necrotizing fasciitis with descending mediastinitis: literature review and case report. J Oral Maxillofac Surg 2012;70:1342-50.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Araştırma Makalesi
Yazarlar

Engin Umut Sakarya Bu kişi benim

Erkan Kulduk Bu kişi benim

Onur Gündoğan Bu kişi benim

Fatih Kemal Soy Bu kişi benim

Rıza Dündar Bu kişi benim

Ahmet Erdem Kılavuz Bu kişi benim

Can Özbay Bu kişi benim

Erdem Eren Bu kişi benim

Abdülkadir İmre Bu kişi benim

Yayımlanma Tarihi 20 Mayıs 2015
Yayımlandığı Sayı Yıl 2015 Cilt: 25 Sayı: 2

Kaynak Göster

APA Sakarya, E. U., Kulduk, E., Gündoğan, O., Soy, F. K., vd. (2015). Derin boyun enfeksiyonunun klinik özellikleri: 77 hastanın analizi. The Turkish Journal of Ear Nose and Throat, 25(2), 102-108.
AMA Sakarya EU, Kulduk E, Gündoğan O, Soy FK, Dündar R, Kılavuz AE, Özbay C, Eren E, İmre A. Derin boyun enfeksiyonunun klinik özellikleri: 77 hastanın analizi. Tr-ENT. Mayıs 2015;25(2):102-108.
Chicago Sakarya, Engin Umut, Erkan Kulduk, Onur Gündoğan, Fatih Kemal Soy, Rıza Dündar, Ahmet Erdem Kılavuz, Can Özbay, Erdem Eren, ve Abdülkadir İmre. “Derin Boyun Enfeksiyonunun Klinik özellikleri: 77 hastanın Analizi”. The Turkish Journal of Ear Nose and Throat 25, sy. 2 (Mayıs 2015): 102-8.
EndNote Sakarya EU, Kulduk E, Gündoğan O, Soy FK, Dündar R, Kılavuz AE, Özbay C, Eren E, İmre A (01 Mayıs 2015) Derin boyun enfeksiyonunun klinik özellikleri: 77 hastanın analizi. The Turkish Journal of Ear Nose and Throat 25 2 102–108.
IEEE E. U. Sakarya, E. Kulduk, O. Gündoğan, F. K. Soy, R. Dündar, A. E. Kılavuz, C. Özbay, E. Eren, ve A. İmre, “Derin boyun enfeksiyonunun klinik özellikleri: 77 hastanın analizi”, Tr-ENT, c. 25, sy. 2, ss. 102–108, 2015.
ISNAD Sakarya, Engin Umut vd. “Derin Boyun Enfeksiyonunun Klinik özellikleri: 77 hastanın Analizi”. The Turkish Journal of Ear Nose and Throat 25/2 (Mayıs 2015), 102-108.
JAMA Sakarya EU, Kulduk E, Gündoğan O, Soy FK, Dündar R, Kılavuz AE, Özbay C, Eren E, İmre A. Derin boyun enfeksiyonunun klinik özellikleri: 77 hastanın analizi. Tr-ENT. 2015;25:102–108.
MLA Sakarya, Engin Umut vd. “Derin Boyun Enfeksiyonunun Klinik özellikleri: 77 hastanın Analizi”. The Turkish Journal of Ear Nose and Throat, c. 25, sy. 2, 2015, ss. 102-8.
Vancouver Sakarya EU, Kulduk E, Gündoğan O, Soy FK, Dündar R, Kılavuz AE, Özbay C, Eren E, İmre A. Derin boyun enfeksiyonunun klinik özellikleri: 77 hastanın analizi. Tr-ENT. 2015;25(2):102-8.