Rhino-orbito-cerebral mucormycosis: two case reports in the light of the literature

Yıl 2015, Cilt: 25 Sayı: 5, 295 - 301, 10.10.2015

Medine Kara Halil Erdoğan Tolgahan Toroslu Alper Akçalı Müşerref Tatman Okun Mustafa Reşorlu Fevzi Sefa Dereköy

Öz

Rhino-orbito-cerebral mucormycosis is an acute onset and often fatal disease. Risk factors include uncontrolled diabetes mellitus, hematological malignancies, and long-term corticosteroid use. Early diagnosis and treatment are important. The underlying causes should be treated, surgical debridement should be performed and appropriate antifungal drugs should be given. In this article, we report two diabetic ketoacidosis patients who developed rhino-orbito-cerebral mucormycosis and were treated with surgical debridement and amphotericin B therapy.

Anahtar Kelimeler

Amphotericin B, rhino-orbito-cerebral mucormycosis, rhizomucor, surgical debridement

Rino-orbito-serebral mukormikozis: Literatür eşliğinde iki olgu sunumu

Öz

Rino-orbito-serebral mukormikozis akut başlayan ve sıklıkla ölümcül olan bir hastalıktır. Risk faktörleri arasında kontrolsüz diyabetes mellitus, hematolojik maligniteler ve uzun süreli kortikosteroid kullanımı yer alır. Erken tanı ve tedavi önemlidir. Altta yatan nedenler tedavi edilmeli, cerrahi debridman yapılmalı ve uygun antifungal ilaçlar verilmelidir. Bu yazıda rino-orbito-serebral mukormikozis gelişen, cerrahi debridman ve amfoterisin B terapisi ile tedavi edilen iki diyabetik ketoasidoz hastası sunuldu

Anahtar Kelimeler

Amfoterisin B, rino-orbito-serebral mukormikozis, rhizomucor, cerrahi debridman

Kaynakça

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