Araştırma Makalesi

Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats

Cilt: 21 Sayı: 1 30 Nisan 2019
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Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats

Öz

The aim of this study was to investigate the effect of L-Caritine supplemented elderly rats on weight loss during 12 weeks. This experimental study was carried out on experimental animals in a scientific laboratory environment, under defined conditions and according to the method of application. Therefore, the model of the research is an experimental research model. In this study, 8 obese aged rats were used for 20 months. Approximately 70 years of human life is equivalent. The rats were given special cholesterol food for obesity. In the study, L-Carnitine was administered to the experimental group 3 times a week just before the exercise, with the daily dose of the sublingual fluid administered to the rats in a suitable dose (1 gr./kg). Before the exercise + L-Carnitine application, weight measurements of the rats were recorded at the beginning of the study (day 1), in the middle of the study (day 45) and finally at the end of the study (day 90). The “IBM SPSS Statistics 22 analiz package program was used to evaluate the statistical analysis of the study. Normal distribution assumptions were evaluated with Kolmogorov-Smirnov and Shapiro-Wilk tests. In the rare cases where the two tests are contradictory, the Kolmogorov-Smirnov test result, which is more preferred in small data sets, was used. Type 1 error margin for normality tests is taken as 0.05. At the end of the study, it was determined that the weight of the old obese rats who used L-Carnitine together with the regular exercise for 12 weeks, both on the 45th and 90th days, was found.

Anahtar Kelimeler

Kaynakça

  1. 1. Adams, S. H., Hoppel, C. L., Lok, K. H., Zhao, L., Wong, S. W., et al. (2009). Plasma acylcarnitine profiles suggest incomplete long‐chain fatty acid beta‐oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African‐American women. J. Nutr. 139, 1073–1081.
  2. 2. Artıs, A.S. (2009). The Relationship Between Proinflammatory Cytokines and Brain Natriuretic Peptide (Bnp) Level in Acute Intensive Exercise, (Unpublished Specialization Thesis), Erciyes University Faculty of Medicine, Department of Physiology, Kayseri, Turkey; 3, 5, 16, 17, 60.
  3. 3. Brownell, KD., Wadden, TA. (1992). Etiology and treatment of obesity: Towards understanding a serious, prevalent and refractory disorder. J Consult Clin Psychol, 60: 505-17.
  4. 4. Halliwell, B. (2001). Free radicals and other reactive species in disease. In: Encyclopedia of life sciences. Ed: J. Wiley & Sons; London: Nature Publishing Group; 1-7.
  5. 5. Hoppel, C. L., and Genuth, S. M. (1980) Carnitine metabolism in normal‐weight and obese human subjects during fasting. Am. J. Physiol. 238, E409–E415.
  6. 6. Hoppel, C. L., and Genuth, S. M. (1982). Urinary excretion of acetylcarnitine during human diabetic and fasting ketosis. Am. J. Physiol. 243, E168–E172.
  7. 7. Lee, B. J., Lin, J. S., Lin, Y. C. & Lin, P. T. (2016). Effects of l‐carnitine supplementation on lipid profiles in patients with coronary artery disease. Lipids Health Dis. 15, 107.
  8. 8. Lindeboom, L., Nabuurs, C. I., Hoeks, J., Brouwers, B., Phielix, E. & al. (2014). Long‐echo time MR spectroscopy for skeletal muscle acetylcarnitine detection. J. Clin. Invest. 124, 4915–4925.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Spor Hekimliği

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

30 Nisan 2019

Gönderilme Tarihi

11 Nisan 2019

Kabul Tarihi

24 Nisan 2019

Yayımlandığı Sayı

Yıl 2019 Cilt: 21 Sayı: 1

Kaynak Göster

APA
Türkay, İ. K., & Başalp, A. (2019). Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats. Turkish Journal of Sport and Exercise, 21(1), 74-77. https://doi.org/10.15314/tsed.552115
AMA
1.Türkay İK, Başalp A. Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats. Turkish Journal of Sport and Exercise. 2019;21(1):74-77. doi:10.15314/tsed.552115
Chicago
Türkay, İbrahim Kubilay, ve Aynur Başalp. 2019. “Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats”. Turkish Journal of Sport and Exercise 21 (1): 74-77. https://doi.org/10.15314/tsed.552115.
EndNote
Türkay İK, Başalp A (01 Nisan 2019) Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats. Turkish Journal of Sport and Exercise 21 1 74–77.
IEEE
[1]İ. K. Türkay ve A. Başalp, “Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats”, Turkish Journal of Sport and Exercise, c. 21, sy 1, ss. 74–77, Nis. 2019, doi: 10.15314/tsed.552115.
ISNAD
Türkay, İbrahim Kubilay - Başalp, Aynur. “Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats”. Turkish Journal of Sport and Exercise 21/1 (01 Nisan 2019): 74-77. https://doi.org/10.15314/tsed.552115.
JAMA
1.Türkay İK, Başalp A. Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats. Turkish Journal of Sport and Exercise. 2019;21:74–77.
MLA
Türkay, İbrahim Kubilay, ve Aynur Başalp. “Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats”. Turkish Journal of Sport and Exercise, c. 21, sy 1, Nisan 2019, ss. 74-77, doi:10.15314/tsed.552115.
Vancouver
1.İbrahim Kubilay Türkay, Aynur Başalp. Effect of l-carnıtıne used ın regular exercıse ın elderly obesıs rats. Turkish Journal of Sport and Exercise. 01 Nisan 2019;21(1):74-7. doi:10.15314/tsed.552115
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