EVALUATION OF Ni LEVELS IN SALIVA AND URINE SAMPLES FROM ORTHODONTIC PATIENTS

Yıl 2017, Cilt: Volume 2 Sayı: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 122 - 122, 16.02.2017

Onur Erdem , Serdar Çetınkaya Mehmet Kaplan Eyüp Çırak Sıla Mermut Gökçe Cemal Akay

Öz

Fixed
nickel-titanium alloy (Ni-Ti) materials are among the frequently used products
in orthodontic treatment. But some metals such as Ni and cobalt (Co) that are
components of orthodontic alloys are well known to be allergenic, cytotoxic,
and mutagenic. Thus, orthodontic patients are exposed to a noticeable amount of
these metals during their treatment depending on construction of materials.
From this perspective the objective of the present study was to evaluate in vivo
corrosive future of these materials. For this purpose, Ni levels were
investigated in saliva and urine samples from the 32 patients (16 boys and 16
girls aged 12-17) who undergoing orthodontic Ni-Ti alloy wire treatment. We
applied a sampling time as follows. For the experimental group, samples were
collected at 7th, 15th and 30th days after the start of treatment with fixed
orthodontic appliances. For the control group, the samples were collected
similarly at 0 day before treatment. We found that the levels of saliva Ni were
statistically significantly constantly higher than beginning of therapy during
orthodontic treatment. Also similar results were determined for urine samples.
In general, our results suggest that a significant level of corrosion occurs from
Ni-Ti alloy wires and this point must be taken into account during orthodontic
therapy. In the future, long-term follow-ups and larger samples of patients are
needed to evaluate these results. At the same time this approach will be useful
for evaluation of biocompatibility of these materials.

Anahtar Kelimeler

EVALUATION OF Ni LEVELS IN SALIVA AND URINE SAMPLES FROM ORTHODONTIC PATIENTS

Kaynakça

• Onur ERDEM, Serdar ÇETINKAYA, Mehmet KAPLAN, Eyüp ÇIRAK, Sıla Mermut GÖKÇE, Cemal AKAY
• Gulhane Military Medical Academy, Department of Pharmaceutical Toxicology, Ankara, TURKEY Gulhane Military Medical Academy, Department of Orthodontics, Ankara, TURKEY Medipol University, Department of Orthodontics, Mega Hospitals Complex, Istanbul, TURKEY