THE EFFECT OF IONIZING RADIATION ON THE NEUROCOGNITIVE STATE AND OXIDATIVE STRESS AND THE QUALITY OF LIFE AMONG WORKERS

Yıl 2017, Cilt: Volume 2 Sayı: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 219 - 219, 16.02.2017

Asma Bahranıfard Ali Akbar Malekırad Samira Shahrjerdı Zeynab Kıanı Kobra Rahzanı Mohammad Abdollahı

Öz

Long-term exposure to ionizing
radiation even with low dosage is associated with mutation and carcinogen
factors. Ionizing radiations via free radicals overproduction and oxidative
stress could lead to increase incidence of numerous diseases. The present study
aimed to compare the neurocognitive state and oxidative stress and quality of
life in workers in compare to control group.

The participants were consisted
of 53 ionizing radiation exposed workers and 41 non exposed workers as control
group. The biochemical parameters, the amount of DNA damage in blood serum, the
neurocognitive parameters by SNI questionnaire, the psychological parameters by
SCL90 and quality of life by SF36 questionnaire were evaluated to investigate
the consequences. The data was analyzed with multivariate variance analysis and
person correlate.

The biochemical parameters
evaluation represented significant reduction in glucose level while the serum
level of aspartat amino transferase has been increased considerably in exposed
workers. The amount of DNA damage revealed no significant diffrences in both
groups. Additionally, there is a direct and significant corrolation between
work history of and DNA damage. The psycological and neurocognitive assessment
proved considerable decrease under influence of inonizing radiation. Quality of
life quesionniare revealed decrease in physical activity with increase pain and
anxiety level.

Consequently, it sounds oxidative
stress due to ionizing radiations have brought detrimental effects on the
psycological and neurocognitive parameters and physical health status. Hence it
is necessary to consider the ioniozing radiation effects on workers metabolic
and neurocognitive status to provide Occupational Health in work places.

Anahtar Kelimeler

THE EFFECT OF IONIZING RADIATION ON THE NEUROCOGNITIVE STATE AND OXIDATIVE STRESS AND THE QUALITY OF LIFE AMONG WORKERS

Kaynakça

• Asma BAHRANIFARD, Ali Akbar MALEKIRAD, Samira SHAHRJERDI, Zeynab KIANI, Kobra RAHZANI, Mohammad ABDOLLAHI
• Natural Hazards Management, Shakhes Pajouh Research Institue, Isfahan, Iran Department of Biology, Payame Noor University, Tehran, Iran Department of Physical Therapy, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran Faculty of Nursing and Midwifery, Arak University of Medical Science, Arak, Iran Department of Toxicology and Pharmacology, Faculty of pharmacy, Pharmaceutical Sciences Research Center, Tehran university of Medical Science, Tehran, Iran