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URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY

Yıl 2017, Cilt: Volume 2 Sayı: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 247 - 247, 16.02.2017

Öz

Nickel is a
potential carcinogenic and very common cause of allergic contact dermatitis.
Human are exposed to nickel primarily via inhalation, ingestion and dermal
absorption. The most encountered nickel exposure sources for general population
are foods, cigarette, jewellery, cosmetics, metal coins, etc. Low concentrated
nickel-plated objects may cause chronic accumulation in the body as a result of
recurrent contacts. On the other hand, urine is the best indicator of chronic
accumulation as an evidence for the exposure to nickel. To the best of our
knowledge, in our country, there hasn’t been a reported study about the urinary
nickel concentrations of nickel sensitized individuals compared in
non-sensitive individuals yet. The aim of this study was to compare the nickel
concentration in urine of patients whose nickel-sensitivity was
dermatologically proven, with non-sensitive group. Nickel patch test was
applied to 388 (61.6% of men) volunteer in dermatology policlinics of
Cerrahpasa Medical Faculty. Test results were positive in 92 (23,7%)
participants. Urine samples were also collected from all participants and
nickel concentrations were determined by Inductively Coupled Plasma-Mass
Spectrometry (ICP-MS). Mean concentrations of nickel-sensitive and non
sensitive people were found 4.48 and 4.26 µg/g creatinine respectively.
Although a significant difference was not found between two groups according to
nickel concentration in urine (p=0.068), results showed that nickel-sensitive
people have higher concentration of nickel in urine than other group as related
studies reported in other countries. This is the first comparative study
evaluating the relationship between urine nickel concentration and nickel
sensitivity in Turkey.

Kaynakça

  • Selda MERCAN, Ugur CELIK, Hayriye ERTEM VEHID, Burhan ENGIN, Sevcan SEMEN, Zeynep TURKMEN, Munevver ACIKKOL
  • 1Istanbul University, Institute of Forensic Sciences, Forensic Toxicology Laboratories, 34098, Cerrahpasa, Istanbul, Turkey 2Istanbul University, Cerrahpasa Medical Faculty, Department of Dermatology, 34098, Cerrahpasa, Istanbul, Turkey 3Istanbul University, Cerrahpasa Medical Faculty, Department of Biostatistics, 34098, Cerrahpasa, Istanbul, Turkey
Yıl 2017, Cilt: Volume 2 Sayı: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 247 - 247, 16.02.2017

Öz

Kaynakça

  • Selda MERCAN, Ugur CELIK, Hayriye ERTEM VEHID, Burhan ENGIN, Sevcan SEMEN, Zeynep TURKMEN, Munevver ACIKKOL
  • 1Istanbul University, Institute of Forensic Sciences, Forensic Toxicology Laboratories, 34098, Cerrahpasa, Istanbul, Turkey 2Istanbul University, Cerrahpasa Medical Faculty, Department of Dermatology, 34098, Cerrahpasa, Istanbul, Turkey 3Istanbul University, Cerrahpasa Medical Faculty, Department of Biostatistics, 34098, Cerrahpasa, Istanbul, Turkey
Toplam 2 adet kaynakça vardır.

Ayrıntılar

Bölüm Articles
Yazarlar

Selda Mercan Bu kişi benim

Ugur Celık Bu kişi benim

Hayriye Ertem Vehıd Bu kişi benim

Burhan Engın Bu kişi benim

Sevcan Semen Bu kişi benim

Zeynep Turkmen Bu kişi benim

Munevver Acıkkol Bu kişi benim

Yayımlanma Tarihi 16 Şubat 2017
Yayımlandığı Sayı Yıl 2017 Cilt: Volume 2 Sayı: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology

Kaynak Göster

APA Mercan, S., Celık, U., Ertem Vehıd, H., Engın, B., vd. (2017). URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY. The Turkish Journal Of Occupational / Environmental Medicine and Safety, Volume 2(İssue 1 (1), 247-247.
AMA Mercan S, Celık U, Ertem Vehıd H, Engın B, Semen S, Turkmen Z, Acıkkol M. URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY. turjoem. Şubat 2017;Volume 2(İssue 1 (1):247-247.
Chicago Mercan, Selda, Ugur Celık, Hayriye Ertem Vehıd, Burhan Engın, Sevcan Semen, Zeynep Turkmen, ve Munevver Acıkkol. “URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY”. The Turkish Journal Of Occupational / Environmental Medicine and Safety Volume 2, sy. İssue 1 (1) (Şubat 2017): 247-47.
EndNote Mercan S, Celık U, Ertem Vehıd H, Engın B, Semen S, Turkmen Z, Acıkkol M (01 Şubat 2017) URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY. The Turkish Journal Of Occupational / Environmental Medicine and Safety Volume 2 İssue 1 (1) 247–247.
IEEE S. Mercan, U. Celık, H. Ertem Vehıd, B. Engın, S. Semen, Z. Turkmen, ve M. Acıkkol, “URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY”, turjoem, c. Volume 2, sy. İssue 1 (1), ss. 247–247, 2017.
ISNAD Mercan, Selda vd. “URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY”. The Turkish Journal Of Occupational / Environmental Medicine and Safety VOLUME 2/İssue 1 (1) (Şubat 2017), 247-247.
JAMA Mercan S, Celık U, Ertem Vehıd H, Engın B, Semen S, Turkmen Z, Acıkkol M. URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY. turjoem. 2017;Volume 2:247–247.
MLA Mercan, Selda vd. “URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY”. The Turkish Journal Of Occupational / Environmental Medicine and Safety, c. Volume 2, sy. İssue 1 (1), 2017, ss. 247-.
Vancouver Mercan S, Celık U, Ertem Vehıd H, Engın B, Semen S, Turkmen Z, Acıkkol M. URINE NICKEL CONCENTRATIONS OF NICKEL-SENSITIVE PATIENTS: A COMPARATIVE STUDY IN TURKEY. turjoem. 2017;Volume 2(İssue 1 (1):247-.