INVESTIGATION OF HISTOPATHOLOGICAL EFFECTS OF ZINC PYRITHIONE ON OREOCHROMIS NILOTICUS (L., 1758)

Yıl 2017, Cilt: Volume 2 Sayı: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 256 - 256, 16.02.2017

Gülten Gün Ramazan Mert

Öz

Zinc pyrithione
(2-mercapto pyridine-N-oxide zinc salt), which has been used in cosmetic
consumer products including anti-dandruff shampoos in many countries for years,
and more recently incorporated in antifouling paints for large boats and ships
due to the ban on tributyltin. However, the toxicity of Zinc Pyrithione (ZnPT)
remains uncertain. In this study, tilapia (Oreochromis niloticus L., 1758)
fingerlings exposed to 1/24 (2.5 μg/L) and 1/12 (5 μg/L) of the 96 hour LC50
value of ZnPT effects were investigated histopatologically. Results of
histological examination, showed no histopatological findings in the gonad,
heart, kidney, muscle, spleen and intestine tissues after subletal ZnPT
exposure, however epithelial lifting, edema, telangiectasia and hyperplasia in
gill tisue; passive hyperemia, hydropic degeneration, lymphocyte infiltration
and fatty degeneration in liver; hyperemia in skin tissues and excessive bile
accumulation in gall bladder were determined. These histopathological findings
have been shown to increase depending on the concentration of the ZnPT.

Anahtar Kelimeler

INVESTIGATION OF HISTOPATHOLOGICAL EFFECTS OF ZINC PYRITHIONE ON OREOCHROMIS NILOTICUS (L.

Kaynakça

• Gülten GÜN, Ramazan MERT
• Nevsehir Haci Bektas Veli University Institute of Science and Technology, Nevsehir, TURKEY Nevsehir Haci Bektas Veli University, Faculty of Arts and Sciences, Department of Biology, Nevsehir, TURKEY