EVALUATION OF BPA LEVELS RELEASED FROM DIFFERENT DENTAL RESTORATIVE MATERIALS USING HPLC METHOD

Yıl 2017, Cilt: Volume 2 Sayı: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 276 - 276, 16.02.2017

Ali Asci Sera Simsek Derelioglu Bilal Yilmaz Taskin Gurbuz Fatma Songur

Öz

Bisphenol A
(BPA) is a chemical produced in large quantities for use primarily in the
production of polycarbonate plastics and epoxy resins. BPA is also present in
dental materials used to treat and prevent caries. There have been concerns
raised regarding the safety of bisphenol A in dental sealants and composites.
The aim of the study is to measure BPA levels which were released from
composite resins after curing with different polymerization conditions. Four
composite resins which are commonly used in dental clinics were used in the
study. The resins were placed into a silicon mold (diameter: 5 mm; thickness: 2
mm) on a teflon plate and photopolymerized by LED light source using two
different modes [Full-Mod (Mod-1) and Ramping Mod (Mod-2)]. After
polymerization, cured composite resin specimens were soaked in 3 ml artificial
saliva and stored at 37 C for 16 days. After 2 h, 24 h, 3 d, 7 d and 15 d, 250
µl specimens were taken in order to detect BPA release from dental resins by
HPLC-UV detection. The linear ranges were found to be 5-2000 ppb. The
regression equation was y=2.6726x-4.6396 (r =0.9993). Maximum and minimum BPA
release from dental composites detected in Mod 1 were 174.04±9.7 and 9.30±0.16
while 10.15±0.3 and 218.0±9.5 in Mod 2, respectively. Release of BPA from
dental restorative materials was ended after 15 days. In conclusion the absence
of a continuous release of BPA from the dental materials is important in the
clinical sense.  

Anahtar Kelimeler

EVALUATION OF BPA LEVELS RELEASED FROM DIFFERENT DENTAL RESTORATIVE MATERIALS USING HPLC METHOD

Kaynakça

• Ali ASCİ, Sera Simsek DERELİOGLU, Bilal YİLMAZ, Taskin GURBUZ, Fatma SONGUR.
• Atatürk University, Faculty of Pharmacy, Department of Toxicology, Erzurum, Turkey Atatürk University, Faculty of Dentistry, Department of Pedodontics, Erzurum, Turkey Atatürk University, Faculty of Pharmacy, Department of Analytical Chemistry, Erzurum, Turkey