AMATOXIN AND PHALLOTOXIN CONTENT OF LEPIOTA CRISTATA

Yıl 2017, Cilt: Volume 2 Sayı: İssue 1 (1) - 2.İnternational Congress Of Forensic Toxicology, 285 - 285, 16.02.2017

Ertugrul Kaya , Ilgaz Akata Nuri Cenk Coskun

Öz

Despite Lepiota
cristata has been known as a nontoxic mushroom species, some researchers have
reported that this species contains the amatoxins. In this study, the amatoxin
and phallotoxin content of the Lepiota cristata growing in Turkey have been
analysed.

The amatoxins
and phallotoxin levels have been measured using the reversed phase high-performance
liquid chromatography system. Toxin analyses were carried out for dried L.
cristata, which were collected from the forests Kastamonu region of Turkey in
2015, as a whole. The alpha amanitin, beta amanitin, gamma amanitin, phalloidin
and phallacidine levels have been analysed.

Detection limits
have been determined as 2.5 ng/g for amatoxins and phallotoxins. Amatoxin and
phallotoxin levels of the mushroom samples have been under the detection
limits.

Some researchers
have reported that the mushroom species of Lepiota cristata contains the
amatoxins and it is lethal mushroom species. Conversely, we have found that in
this study, Lepiota cristata does not contain any amatoxins or phallotoxins
(alpha amanitin, beta amanitin, gamma amanitin, phalloidin and phallacidin).
New researches about the how toxin content of the Lepiota cristata may be
useful in order to understand of toxicity of this species.

Anahtar Kelimeler

AMATOXIN AND PHALLOTOXIN CONTENT OF LEPIOTA CRISTATA

Kaynakça

• Ertugrul KAYA, Ilgaz AKATA, Nuri Cenk COSKUN
• Duzce University, Faculty of Medicine, Department of Pharmacology Ankara University, Faculty of Science, Department of Biology