Many of
the chemicals in the environment can alter hormonal homeostasis of living
beings. Pesticides use in health and agriculture has very varied effects:
benefits derived from the systematic destruction of parasites that affect the
health of plants and humans must be set against the effects of them on animal
species and humans. Despite legislation to control the use of certain products,
they repeatedly appear in the adipose tissue, milk, and serum of animal and
human populations. Because organochlorine pesti-cides accumulate in the adipose
tissue, blood/serum, and milk, any of these media are suitable for estimating
human impregnation by these xenobiotics, and studies have demonstrated the
presence of polychlorinatedbi-phenyls (PCBs), dioxins, DDT, and HCH in all of
them. Synthetic chemicals are transfered from mother to child across placenta
and breast milk and may disrupt development even at low levels. For the fetus
and neonate, exposures to environmental toxicants may result in a wide range of
adverse health consequences and potentially be transmitted to the next generation.
Although cord blood can provide information about fetal exposure at birth, it
may not accurately reflect fetal exposures during early gestation, which may
also have profound developmental effects. Recent studies have collected data on
environmental exposures during pregnancy but few have adequately characterized
cumulative exposures and their consequent effects on developing fetus. Future
research should focus on characterizing cumulative maternal and fetal exposure
from preconception to postpartum and investigating possible additive or
multiplicative clinical effects of multiple cumulative exposures using
appropriate statistical tools. Moreover, educational materials on chemical
exposures should focus on modifiable risk factors, such as diet. Because synthetic
chemicals are now global contaminants,it is increasingly important to create
opportunities for environmental health prevention through understanding and
ultimately reducing cumulative exposures during pregnancy and early
development.
Keywords:
pregnant,
pesticide, fetus
Bölüm | Articles |
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Yazarlar | |
Yayımlanma Tarihi | 1 Şubat 2017 |
Yayımlandığı Sayı | Yıl 2017 Sayı: Issue 1(2) - 3. INTERNATIONAL BIOCIDAL CONGRESS |