Helichrysum armenium species used in alternative medicine (Altınotu) phenolic content and antioxidant properties

Yıl 2024, Cilt: 11 Sayı: 2, 490 - 496, 30.04.2024

Fatma Ergün , Melike Yeğin

https://doi.org/10.30910/turkjans.1355478

Öz

Radical accumulation is among the causes of chronic diseases in living organisms. These radicals formed as a result of metabolic activities must be neutralized and removed from the environment in order to reduce or eliminate their harmful effects on the organism. This is possible thanks to natural antioxidants. The knowledge of this situation has led to an increased interest in natural antioxidant sources and many studies have been conducted. Helichrysum armenium subsp. armenium is a species of the Asteraceae family with medicinal and aromatic properties with antioxidant potential. It has a wide distribution worldwide and is used in traditional medicine for various folkloric purposes. The phenolic and flavonoid content of the extract of this plant species used in our study was 87.60±0.10 mg GAE g-1 and 38.84±1.36 mg QE g-1, respectively. IC50 value of the plant extract was 183.07±4.92 µg ml-1, Fe+3 reducing power was 2.36±0.20 µg TE ml-1, Cu+2 reducing power was 40.94±4.62 µg TE ml-1, DPPH radical scavenging activity was 24.05+1.13 µg TE ml-1. In addition, vitamin C value was determined as 17.2 mg 100 g-1. These results reveal the richness of the biochemical content of Helichrysum armenium subsp. armenium taxon. Considering the results, it is concluded that the intense interest in other sub-taxa of the genus Helichrysum should also be shown to this species. Further studies are also needed to determine the health impacts of this species.

Anahtar Kelimeler

Antioxidant, Phytochemicals, Helichrysum armenium subsp. armenium, Altınotu, Ölmezotu

Alternatif Tıpta Kullanılan Helichrysum armenium Türünün (Altınotu) Fenolik İçerik ve Antioksidan Özellikleri

Öz

Canlılardaki kronik hastalıkların oluşma sebepleri arasında radikal akümülasyonu gelmektedir. Metabolik faaliyetler sonucu oluşan bu radikallerin organizma üzerindeki zararlı etkilerinin azaltılması veya yok edilmesi için nötrleştirilip ortamdan uzaklaştırılması gerekir. Buda doğal antioksidanlar sayesiyle mümkündür. Bu durumun bilinmesi doğal antioksidan kaynaklarına ilginin artmasına ve birçok çalışmanın yapılmasına neden olmuştur. Helichrysum armenium subsp. armenium, Asteraceae familyasına ait antioksidan potansiyele sahip tıbbi ve aromatik özellikleri olan bir türdür. Dünya çapında geniş bir dağılıma sahip olan bu bitki, geleneksel tıpta çeşitli folklorik amaçlar için kullanılmaktadır. Çalışmamızda kullanılan bu bitki türü ekstraktının fenolik madde miktarının 87,60±0,10 mg GAE g-1 ve flavonoid madde miktarının 38,84±1,36 mg KE g-1 olduğu belirlenmiştir. Bitki ekstraktının, IC50 değerinin 183,07±4,92 µg mL-1, Fe+3 indirgeme gücünün 2,36±0,20 µg TE/ml, Cu+2 indirgeme gücünün 40,94±4,62 µg TE mL-1, DPPH radikal giderme aktivitesinin ise 24,05+1,13 µg TE mL-1 olduğu tespit edilmiştir. Ayrıca C vitamini değeri 17,2 mg 100 g-1 olarak belirlendi. Bu sonuçlar, Helichrysum armenium subsp. armenium taksonunun biyokimyasal içeriğinin zenginliğini ortaya koymaktadır. Sonuçlar dikkate alındığında daha çok Helichrysum cinsinin diğer alt taksonlarına olan yoğun ilginin, bu türe karşıda gösterilmesi gerekliliği kanaati oluşmuştur. Ayrıca bu türün sağlık üzerindeki etkilerini belirlemek amacıyla yeni çalışmaların yapılmasına ihtiyaç vardır.

Anahtar Kelimeler

Antioksidan, Fitokimyasallar, Helichrysum armenium subsp. armenium, Altınotu, Ölmezotu

Kaynakça

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