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Active Status of HMB Supplementation on Aerobic Capacity, Blood Parameters, Low and High Intense Body Muscle Oxygen and Energy Ergometer: A Systematic Review and Fixed Model Effect Meta-Analysis

Yıl 2022, Cilt: 3 Sayı: 3, 97 - 107, 31.12.2022

Öz

HMB (β-hydroxy-β-methylbutyric acid) ergojenik takviyesi, insanın aerobic vücut metabolizması, düşük ve yüksek yoğun kas oksijeni ve enerji ergometresi üzerinde oldukça etkilidir. Ancak, HMB takviyesinin aerobic kapasite, kan laktat birikimi ve diğer kan enzim aktivite düzeyleri üzerindeki aktif durumu sporcularda ve fiziksel bireylerde belirsizdir. Bu çalışma, sabit model etkili meta-analiz altında gerçekleştirilmiştir. HMB takviyesinin aktif durumu, sporcular ve fiziksel bireyler için çalışmalarla (n=194) önyargı çözme riskinin metadolojik kalitesi aracılığıyla analiz edildi. Sabit model etkisi için kullanılan ortak popülasyon etki büyüklüğü, ortalama farkı ve etki büyüklüğü yerine getirildi, ayrıca sadece örneklem düzeyi ve minimum etki analiz edildi. Parametrik değişkenler için popülasyon etki büyüklüğü Cohen’d kullanıldı, ancak bu çalışmada VO2max ES= 0.32 orta, heterojenite I2 =70.41, ortalama fark = -0.12, ayrıca diğer parameter HRVT ES= 1.61 büyük, heterojenite I2 = 9.01, ortalama fark = 1.65 bulunmuştur.

Kaynakça

  • Albert, F. J., Morente-Sánchez, J., Ortega, F. B., Castillo, M. J. & Gutiérrez, Á. (2015). A Usefulness of β-hydroxy-β-methylbutyrate (HMB) supplementation in different sports: Anupdate and practical implications. Nutricion hospitalaria, 32(1), 20–33. https://doi.org/10.3305/nh.2015.32.1.9101.
  • Borenstein, M, Hedges, L.V., Higgins, J.P. & Rothstein, H.R. (2009). Introduction to metaanalysis. John Wiley & Sons, Ltd. 61-117.
  • Broatch, J. R., Poignard, M., Hausswirth, C., Bishop, D. J. & Bieuzen, F. (2019). Wholebody cryotherapy does not augment adaptations to high-intensity interval training. Scientific reports, 9(1), 12013. https://doi.org/10.1038/s41598-019-48518-1.
  • Deutz, N. E., Pereira, S. L., Hays, N. P., Oliver, J. S., Edens, N. K., Evans, C. M., & Wolfe, R. R. (2013). Effect of β-hydroxy-β-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults. Clinical nutrition (Edinburgh, Scotland), 32(5), 704– 712. https://doi.org/10.1016/j.clnu.2013.02.011.
  • Durkalec-Michalski, K. & Jeszka, J. (2015). The efficacy of a β-hydroxy-β-methylbutyrate supplementation on physical capacity, body composition and biochemical markers in elite rowers: a randomised, double-blind, placebo-controlled crossover study. Journal of the International Society of Sports Nutrition, 12, 31. https://doi.org/10.1186/s12970- 015-0092-9.
  • Durkalec-Michalski, K. & Jeszka, J. (2016). The Effect of β-hydroxy-β-methylbutyrate on aerobic capacity and body composition in trained athletes. Journal of Strength and Conditioning Research, 30(9), 2617–2626.
  • Durkalec-Michalski, K., Jeszka, J., & Podgórski, T. (2017). The Effect of a 12-Week Betahydroxy- beta-methylbutyrate (HMB) Supplementation on highly-trained combat sports athletes: A randomised, double-blind, placebo-controlled crossover study. Nutrients, 9(7), 753.https://doi.org/10.3390/nu9070753.
  • He, X., Duan, Y., Yao, K., Li, F., Hou, Y., Wu, G. & Yin, Y. (2016). β-Hydroxy-βmethylbutyrate, mitochondrial biogenesis, and skeletal muscle health. Amino acids, 48(3), 653– 664. https://doi.org/10.1007/s00726-015-2126-7.
  • Herzig, S. & Shaw, R. J. (2018). AMPK: guardian of metabolism and mitochondrial homeostasis. Nature reviews. Molecular cell biology, 19(2), 121–135. https://doi.org/10.1038/nrm.2017.95.
  • Higgins, J. P. T., Altman, D. G., Gotzsche, P. C., Juni, P., Moher, D. & Oxman, A. D. (2011). The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ, 343(oct18 2), d5928–d5928. doi:10.1136/bmj.d5928.
  • Holeček, M. (2017). Beta-hydroxy-beta-methylbutyrate supplementation and skeletal muscle in healthy and muscle-wasting conditions. Journal of Cachexia, Sarcopenia and Muscle, 8(4), 529–541. https://doi.org/10.1002/jcsm.12208.
  • Hung, W., Liu, T.H., Chen, C.Y. & Chang, C.K. (2010). Effect of β-hydroxy-βmethylbutyrate supplementation during energy restriction in female judo athletes. Journal Exercise Science and Fitness. 8(1), 50-53.
  • Kaczka, P., Michalczyk, M. M., Jastrząb, R., Gawelczyk, M. & Kubicka, K. (2019). Mechanism of action and the effect of beta-hydroxy-beta-methylbutyrate (HMB) supplementation on different types of physical performance - A systematic review.
  • Journal of Human Kinetics, 68, 211–222. https://doi.org/10.2478/hukin-2019-0070. 107 Knitter, A. E., Panton, L., Rathmacher, J. A., Petersen, A. & Sharp, R. (2000). Effects of beta-hydroxy-beta-methylbutyrate on muscle damage after a prolonged run. Journal of Applied Physiology (Bethesda, Md. : 1985), 89(4), 1340–1344.
  • Miller, P., Sandberg, L. & Fuller Jr J.C. (1997). The effect of intensive training and Bhydroxy- B-methylbutyrate (HMB) on the physiological response to exercise in horse. FASEB J, 1: A290.
  • Lamboley, C. R., Royer, D. & Dionne, I. J. (2007). Effects of beta-hydroxy betamethylbutyrate on aerobic-performance components and body composition in college students. International Journal of Sport Nutrition and Exercise Metabolism, 17(1), 56–69. https://doi.org/10.1123/ijsnem.17.1.56.
  • O’Connor, D. M. & Crowe, M.J. (2003) Effect of B-hydroxy-B-methylbutyrate and creatine monohydrate supplementation on the aerobic and anaerobic capacity of highly trained athletes. Journal of Sport Medicine and Physical Fitness. 43, 64-8.
  • Robinson, E. H., Stout, J. R., Miramonti, A. A., Fukuda, D. H., Wang, R., Townsend, J. R., Mangine, G. T., Fragala, M. S. & Hoffman, J. R. (2014). High-intensity interval training and β-hydroxy-β-methylbutyric free acid improves aerobic power and metabolic thresholds. Journal of the International Society of Sports Nutrition, 11, 16. https://doi.org/10.1186/1550-2783-11-16.
  • Rothschild, J. A., Islam, H., Bishop, D. J., Kilding, A. E., Stewart, T. & Plews, D. J. (2022). Factors Influencing AMPK Activation During Cycling Exercise: A Pooled Analysis and Meta-Regression. Sports medicine (Auckland, N.Z.), 52(6), 1273–1294.
  • Tadaishi, M., Miura, S., Kai, Y., Kano, Y., Oishi, Y. & Ezaki, O. (2011). Skeletal musclespecific expression of PGC-1α-b, an exercise-responsive isoform, increases exercise capacity and peak oxygen uptake. PloS One, 6(12), e28290. https://doi.org/10.1371/journal.pone.0028290.
  • Thorlund, K., Imberger, G., Johnston, B. C., Walsh, M., Awad, T., Thabane, L., Gluud, C., Devereaux, P. J. & Wetterslev, J. (2012). Evolution of heterogeneity (I2) estimates and their 95% confidence intervals in large meta-analyses. PloS one, 7(7), e39471. https://doi.org/10.1371/journal.pone.0039471.
  • Vukovich, M. D. & Dreifort, G. D. (2001). Effect of beta-hydroxy beta-methylbutyrate on the onset of blood lactate accumulation and VO2 peak in endurance-trained cyclists. Journal of Strength and Conditioning Research, 15(4), 491–497.
  • Wilson, J. M., Fitschen, P. J., Campbell, B., Wilson, G. J., Zanchi, N., Taylor, L., Wilborn, C., Kalman, D. S., Stout, J. R., Hoffman, J. R., Ziegenfuss, T. N., Lopez, H. L., Kreider, R. B., Smith-Ryan, A. E. & Antonio, J. (2013). International society of sports nutrition position stand: beta-hydroxy-beta-methylbutyrate (HMB). Journal of the International Society of Sports Nutrition, 10(1), 6. https://doi.org/10.1186/1550-2783-10-6.
Toplam 23 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Egzersiz ve Spor Psikolojisi
Bölüm 2022 Cilt: 3 Sayı : 3
Yazarlar

Yeliz Kahraman Bu kişi benim

Harun Ertören Bu kişi benim

Yayımlanma Tarihi 31 Aralık 2022
Yayımlandığı Sayı Yıl 2022 Cilt: 3 Sayı: 3

Kaynak Göster

APA Kahraman, Y., & Ertören, H. (2022). Active Status of HMB Supplementation on Aerobic Capacity, Blood Parameters, Low and High Intense Body Muscle Oxygen and Energy Ergometer: A Systematic Review and Fixed Model Effect Meta-Analysis. Uluslararası Bozok Spor Bilimleri Dergisi, 3(3), 97-107.