Meta-analysis for Searching Efficacy of Tinidazole and Metronidazole

Yıl 2017, , 32 - 38, 01.04.2017

Humaira Zafar Kiran Tauseef Bukhari Nouman Noor Sadaf Humayoun Noor Khan Lakhnana

https://doi.org/10.5455/umj.20170607081427

Öz

The 5-nitroimidazole antimicrobial agents are considered as the treatment of choice for managing the amebic, protozoal and anerobic infections since 1969. With the advancement in medical field certain preference of drugs in this group were given. Tinidazole is now considered as a better one as compared to metronidazole because of specific pharmacokinetic & pharmacodynamics properties. Therefore the current study was hypothesized that tinidazole is a better option for managing anaerobic, amebic and protozoal infection as compared to metronidazole.

Anahtar Kelimeler

Tinidazole, Metronidazole, Comparative efficacy, Anaerobic infection, Amebic infection, Protozoal infection

Kaynakça

• Sim Fung HB, Doan TL, Malar J. Tinidazole: a nitroimida zole antiprotozoal agent.Clin Ther. 2005;27(12):1859-84.
• Löfmark S, Edlund C, Nord CE. Metronidazole is still the drug of choice for treatment of anaerobic infections. Clin Infect Dis. 2010;50(1):16–23.
• Armstrong NR, Wilson JD. Tinidazole in the treatment of bacterial vaginosis. Int J Womens Health. 2010;1(1):59–65.
• Armstrong NR,Wilson JD. Tinidazole in the treatment of bacterial vaginosis. Int J Womens Health. 2011; 3(2): 295– 305.
• Menard JP. Antibacterial treatment of bacterial vaginosis: current and emerging therapies. Int J Womens Health. 2009; 1(1): 59–65.
• Raja IM, Basavareddy A, Mukherjee D, Meher BR. Rando- mized, double-blind, comparative study of oral metroni- dazole and tinidazole in treatment of bacterial vaginosis. Indian J Pharmacol 2016;48 (6):654-8.
• Macareo L, Lwin KM, Cheah PY, Yuentrakul P, Miller RS, Nosten F etal. Triangular test design to evaluate tinidazole in the prevention of Plasmodium vivax relapse. Malar J. 2013; 12(4): 173.
• Livengood CH, Ferris DG, Wiesenfeld HC. Effectiveness of two tinidazole regimens in treatment of bacterial vagino- sis: a randomized controlled trial. Obstet Gynecol. 2007; 110 (3):302–309.
• Oduyebo OO, Anorlu RI, Ogunsola FT. The effects of antimicrobial therapy on bacterial vaginosis in nonpreg- nant women. Cochrane Database Syst Rev. 2009;3(4): 55-60.
• Brandt M, Abels C, May T, Lohmann K, Winkler SI, Hoyme UB etal. Intravaginally applied metronidazole is as effective as orally applied in the treatment of bacterial vaginosis, but exhibits significantly less side effects. Eur J Obstet Gynecol Reprod Biol. 2008;141(5):158–162.
• Hanson JM, Gregor MJA, Hillier SL. Metronidazole for bacterial vaginosis. A comparison of vaginal gel vs oral therapy. J Reprod Med. 2000;45(2):889–896.
• Buranawarodomkul P, Chandeying V, Sutthijumroon S. Seven day metronidazole versus single dose tinidazole as therapy for nonspecific vaginitis. J Med Assoc Thai. 1990;73(1):283–7.
• Sanz SF, Hernanz A, Sancher E. Comparative trial of metronidazole versus tinidazole in the treatment of non specific vaginitis. Rev Esp Obst y Gin. 1985;44(1):717–20.
• Thulkar J, Kriplani A, Agarwal N. A comparative study of oral single dose of metronidazole, tinidazole, secnidazole and ornidazole in bacterial vaginosis. Indian J Pharmacol 2012;44(2):243-5
• Bakshi JS, Ghiara, JM, Nanivadekar AS. How Does Tinidazole Compare with Metronidazole? Drugs.1978; 15(1): 33–42
• Bhalla P, Chawla R, Garg S, Singh MM, Raina U, Bhalla R, et al. Prevalence of bacterial vaginosis among women in Delhi. Indian J Med Res. 2007;125(2):167–72.
• Australasian College of Sexual Health Physicians: Clinical Guidelines for the management of sexually transmissible infections among priority populations 2004. Website: http://www.wsahs.nsw.gov.au/services/sexualhealth/docu ments/STI_Management_Priority_Populations_000.pdf. Retrieved on 23rd March 2017.
• United Kingdom National Guideline for the management of bacterial vaginosis 2006. Website: http://www.bashh.org /documents/62/62.pdf. Retrieved on 24th March 2017
• CDC Sexually transmitted diseases treatment guidelines MMWR 2006 RR-11.
• Website:[ http://www.cdc.gov/std/treatment/2006/vaginal- discharge.htm#vagdis2.] Retrieved on 24th March 2017
• Ottawa ON: Public Health Agency of Canada; Canadian Guidelines on Sexually Transmitted Infections. [Revised January 2008]
• Website:[http://www.phac-aspc.gc.ca/std-mts/sti_2006/pdf /408_Vaginal_Discharge.pdf]. Retrieved on24th March 2017
• Food and Drug Administration. Website:http://accessdata. fda.gov/drugsatfda_docs/label/2007/021618s003lbl.pdf. Retrieved on 24th March 2017.
• Tinidazole tablets for infection. Website: http:patient.info/ medicine/tinidazole-tablets-for-infection-fasigyn–patient- UK] Retrieved on 24th March 2017
• Tinidazole.Website https://medlineplus.gov/druginfomeds /a604036.html. Retrieved on 24th March 2017
• Metronidazole. Website: www.petmd.com/pet-medication /metronidazole. Retrieved on 24th March 2017
• Manso F, Gamboa MS, Giménez M, Bascones A, Lus GML, Aguilar L.Why not revisiting tinidazole as potential treatment of odontogenic infections? Rev Esp Quimioter. 2008;21(3):198-202.
• Odeh NSR. Abdalla O, Hammad A, Khaleed Khraisat S, etal. Antibiotic prescribing practices by dentists: a review. Clin Risk Manag. 2010; 6(2): 301–306.
• Patait M, Urvashi N, Rajderkar M, Kedar S, Shah K, Patait R. Antibiotic prescription: An oral physician's point of view. J Pharm Bioallied Sci. 2015;7(2):116-20.
• Egea SJJ, Gould K, Şen BH, Jonasson P, Cotti E, Mazzoni A, etal. Antibiotics in Endodontics: a review. Int Endod J. 2016
• Falkenstein S, Stein JM, Henne K, Conrads G.Trends in antibiotic use and microbial diagnostics in periodontal treatment: comparing surveys of German dentists in a ten- year period. Clin Oral Investig. 2016;20(8):2203-2210.
• Rasteriene R. A 10yera retrospective analysis. Surg Infect. 2015; 16(3): 305-312.
• Barak O, Dashper SG, Catmull DV, Adams GG, Sela MN, Machtei EE, etal. Antibiotic susceptibility of Aggregati bacter actinomycetemcomitans JP2 in a biofilm. J Oral Microbiol. 2013; 8(1):5-32
• Rams TE, Degener JE, Winkelhoff VAJ. Antibiotic resistance in human chronic periodontitis microbiota. J Periodontol.2014;85(1):160-9.