Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2020, , 119 - 124, 19.09.2020
https://doi.org/10.5455/umj.20200716093218

Öz

Kaynakça

  • Obi-Ezeani CN, Dioka CE, Meludu SC, Onuora IJ, Usman SO, Onyema-Iloh OB. Blood pressure and lipid profile in automechanics in relation to lead exposure. Indian J Occup Environ Med 2019;23:28-31
  • Agbecha A, Ameh AE. Atherogenic indices and smoking habits in cigarette smokers. Environmental Disease. 2018;3: 38-44
  • Yu S, Zhu L, Wang K, Yan Y, He J, Ren Y. Green tea consumption and risk of breast cancer. A systematic review and updated meta-analysis of case-control studies. Medicine. 2019;98(27):e16147
  • Ataee R, Ataie A Shahidian M, Gorgi AH. Role of green tea as anti-oxidative stress agent in neurodegenerative diseases. MOJ Toxicol. 2018;4(6):365-366
  • Onuora IJ, Meludu SC, Dioka CE, Obi-Ezeani CN, Usman SO. Evaluation of insulin, malondialdehyde and blood pressure in male obese individuals in Nnewi and subsequent effect of green tea supplementation. Asian Journal of Research in Medical and Pharmaceutical Sciences. 2018;3(3):1-7
  • Obi-Ezeani CN, Dioka CE, Meludu SC, Onuora IJ, Usman SO. Effect of green tea supplementation on blood cadmium and male sex hormone levels in automobile workers in Emene, Enugu State, Nigeria. J Adv Med Med Res 2018;27:1-7
  • Roeschlaw P, Bernt E, Gruber JW. Enzymatic determination of total cholesterol in serum. J Clin Chem Clin Biochem 1974;12:226-403
  • Grove TH. Effect of reagent pH on determination of HDL-C by precipitation with sodium-phosphotungstate-magnesium. Clin Chem 1979;25:560
  • Fossati P, Prencipe L. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 1982;28:2077-80
  • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502
  • Bhardwaj S, Bhattacharjee J, Bhatnagar MK, Iyagi S. Atherogenic index of plasma, Castelli risk index atherogenic co-efficient – new parameters in assessing cardiovascular risk. Int J Pharm Bio Sci. 2013;3:359-364
  • Ugbaja RN, Onunkwo BO, Omoniyi DA. Lead induced dyslipidemia: The comparative effects of ascorbate and chelation therapy. African Journal of Biotechnology. 2013;12(15):1845-1852
  • Sharma SV, Kumar P, Atam V, Verma A, Murthy RC. Lipid profiles with increased blood lead levels: Risk of cardiovascular disease in battery workers of Lucknow City. J Indian Acad Forensic Med 2012;34(4):328-331
  • Adejumo BI., Osagie I, Dimkpa U, Emmanuel AM. Lipid profile and atherogenic indices of commercial automobile battery recyclers (battery chargers), automobile mechanics and spray, Edo State, Nigeria. Nigerian Biomedical Science Journal. 2016;12(2):39-42
  • Dobiasova M. AIP-atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice. Vnitr Lek. 2006;52(1):64-71
  • Dobiasova M, Frohlich J, Sedova M, Cheung MC, Brown BG. Cholesterol esterification and atherogenic index of plasma correlate with lipoprotein size and findings on coronary angiography. J Lipid Res. 2011;52:566-571
  • Frejnagel S, Wroblewska M. Comparative effect of green tea chokeberry and honeysuckle polyphenols on nutrients and mineral absorption and digestibility in rats. Annals of Nutrition and Metabolism. 2010;56:163-169
  • Koo SI, and Noh SK. Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid- lowering effect. Journal of Nutritional Biochemistry. 2007; 18(3):179-183
  • Singh DK, Banerjee S, Porter TD. Green and black tea extracts inhibit HMG-CoA reductase and activate AMP-kinase to decrease cholesterol synthesis in hepatoma cells. Journal of Nutritional Biochemistry. 2009;20(10):816-822
  • Ge H, Liu J, Zhao W, Wang Y, He Q, Wu R, Li D, Xu J. Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols. Organic and Bimolecular Chemistry. 2014;12 (27):4941-4951
  • Zhou J, Kong C, Hou X, Zhang Z, He F. Green tea effects on the levels of serum glucose and lipid profiles. American Journal of Medical Sciences and Medicine. 2016;4(3):59-62.
  • Senger AE., Schwanke CHA, Gomes I, Vale Gottlieh MG. Effect of green tea (Camellia sinensis) consumption on the syndrome in elderly. Journal of utrition Health and Aging. 2012;16:738-742

Evaluation of Lipid Profile and Atherogenic Indices of Automobile Workers Before and after Green Tea Supplementation

Yıl 2020, , 119 - 124, 19.09.2020
https://doi.org/10.5455/umj.20200716093218

Öz

Introduction: The various toxic chemicals automobile workers (AMW) are exposed to may predispose them to some adverse cardiovascular outcomes by alteration of lipids and lipoproteins. However, dietary strategies may be useful in preventing this undesirable outcome.
Materials & Methods: The study aimed to assess the lipid profile and atherogenic indices of automobile workers. 78 male subjects aged 18 to 54 years, 33 automobile workers (AMW), and 45 control subjects were recruited for this study. 28 out of the 33 automobile workers received 150 ml of green tea daily for two months. 3ml of fasting blood samples were collected before and after one and two months of intervention. Total cholesterol (TC), high-density lipoprotein cholesterol (HDLc), and triglyceride (TG) were measured enzymatically while low-density lipoprotein cholesterol (LDLc) and atherogenic indices (Castelli’s risk index (CRI) 1 and 2, atherogenic coefficient (AC), atherogenic index of plasma (AIP), non-HDLc (nHDLc) were calculated.
Results: The median values of TC, LDLc, TG, CRI-1, CRI-2, AC, AIP, and nHDLc were significantly higher in the automobile workers when compared to the control (p<0.05), however, the median HDLc level was not significantly different in both groups (p=0.083). TC, LDLc, TG, CRI-1, CRI-2, AC, AIP, and nHDLc decreased significantly after one and two months of green tea intake whereas HDLc level increased significantly after two months of intake (p<0.05).
Conclusion: This study suggests that automobile workers are at higher risk of developing cardiovascular disorders, however, green tea supplements may possess anti-atherogenic properties for attenuating cardiovascular risk in these workers.

Kaynakça

  • Obi-Ezeani CN, Dioka CE, Meludu SC, Onuora IJ, Usman SO, Onyema-Iloh OB. Blood pressure and lipid profile in automechanics in relation to lead exposure. Indian J Occup Environ Med 2019;23:28-31
  • Agbecha A, Ameh AE. Atherogenic indices and smoking habits in cigarette smokers. Environmental Disease. 2018;3: 38-44
  • Yu S, Zhu L, Wang K, Yan Y, He J, Ren Y. Green tea consumption and risk of breast cancer. A systematic review and updated meta-analysis of case-control studies. Medicine. 2019;98(27):e16147
  • Ataee R, Ataie A Shahidian M, Gorgi AH. Role of green tea as anti-oxidative stress agent in neurodegenerative diseases. MOJ Toxicol. 2018;4(6):365-366
  • Onuora IJ, Meludu SC, Dioka CE, Obi-Ezeani CN, Usman SO. Evaluation of insulin, malondialdehyde and blood pressure in male obese individuals in Nnewi and subsequent effect of green tea supplementation. Asian Journal of Research in Medical and Pharmaceutical Sciences. 2018;3(3):1-7
  • Obi-Ezeani CN, Dioka CE, Meludu SC, Onuora IJ, Usman SO. Effect of green tea supplementation on blood cadmium and male sex hormone levels in automobile workers in Emene, Enugu State, Nigeria. J Adv Med Med Res 2018;27:1-7
  • Roeschlaw P, Bernt E, Gruber JW. Enzymatic determination of total cholesterol in serum. J Clin Chem Clin Biochem 1974;12:226-403
  • Grove TH. Effect of reagent pH on determination of HDL-C by precipitation with sodium-phosphotungstate-magnesium. Clin Chem 1979;25:560
  • Fossati P, Prencipe L. Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clin Chem 1982;28:2077-80
  • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 1972;18:499-502
  • Bhardwaj S, Bhattacharjee J, Bhatnagar MK, Iyagi S. Atherogenic index of plasma, Castelli risk index atherogenic co-efficient – new parameters in assessing cardiovascular risk. Int J Pharm Bio Sci. 2013;3:359-364
  • Ugbaja RN, Onunkwo BO, Omoniyi DA. Lead induced dyslipidemia: The comparative effects of ascorbate and chelation therapy. African Journal of Biotechnology. 2013;12(15):1845-1852
  • Sharma SV, Kumar P, Atam V, Verma A, Murthy RC. Lipid profiles with increased blood lead levels: Risk of cardiovascular disease in battery workers of Lucknow City. J Indian Acad Forensic Med 2012;34(4):328-331
  • Adejumo BI., Osagie I, Dimkpa U, Emmanuel AM. Lipid profile and atherogenic indices of commercial automobile battery recyclers (battery chargers), automobile mechanics and spray, Edo State, Nigeria. Nigerian Biomedical Science Journal. 2016;12(2):39-42
  • Dobiasova M. AIP-atherogenic index of plasma as a significant predictor of cardiovascular risk: from research to practice. Vnitr Lek. 2006;52(1):64-71
  • Dobiasova M, Frohlich J, Sedova M, Cheung MC, Brown BG. Cholesterol esterification and atherogenic index of plasma correlate with lipoprotein size and findings on coronary angiography. J Lipid Res. 2011;52:566-571
  • Frejnagel S, Wroblewska M. Comparative effect of green tea chokeberry and honeysuckle polyphenols on nutrients and mineral absorption and digestibility in rats. Annals of Nutrition and Metabolism. 2010;56:163-169
  • Koo SI, and Noh SK. Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid- lowering effect. Journal of Nutritional Biochemistry. 2007; 18(3):179-183
  • Singh DK, Banerjee S, Porter TD. Green and black tea extracts inhibit HMG-CoA reductase and activate AMP-kinase to decrease cholesterol synthesis in hepatoma cells. Journal of Nutritional Biochemistry. 2009;20(10):816-822
  • Ge H, Liu J, Zhao W, Wang Y, He Q, Wu R, Li D, Xu J. Mechanistic studies for tri-targeted inhibition of enzymes involved in cholesterol biosynthesis by green tea polyphenols. Organic and Bimolecular Chemistry. 2014;12 (27):4941-4951
  • Zhou J, Kong C, Hou X, Zhang Z, He F. Green tea effects on the levels of serum glucose and lipid profiles. American Journal of Medical Sciences and Medicine. 2016;4(3):59-62.
  • Senger AE., Schwanke CHA, Gomes I, Vale Gottlieh MG. Effect of green tea (Camellia sinensis) consumption on the syndrome in elderly. Journal of utrition Health and Aging. 2012;16:738-742
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Original Articles
Yazarlar

Chikaodili Nwando Obı-ezeanı Bu kişi benim 0000-0002-9581-0051

Samuel Chukwuemeka Meludu Bu kişi benim 0000-0001-5547-4156

Emmanuel Chudi Dıoka Bu kişi benim 0000-0002-5367-0943

Yayımlanma Tarihi 19 Eylül 2020
Gönderilme Tarihi 16 Temmuz 2020
Yayımlandığı Sayı Yıl 2020

Kaynak Göster

Vancouver Obı-ezeanı CN, Meludu SC, Dıoka EC. Evaluation of Lipid Profile and Atherogenic Indices of Automobile Workers Before and after Green Tea Supplementation. ULUTAS MED J. 2020;6(3):119-24.