A Rarely Seen Hepatic Tumor: Epithelioid Hemangioendothelioma

Yıl 2016, Cilt: 2 Sayı: 1, 59 - 62, 01.01.2016

Erdinc Nayir

https://doi.org/10.5455/umj.20160121062843

Öz

Introduction: Epithelioid Hemangioendothelioma EHE is a rarely seen tumor most frequently originating from vascular structures of different regions including liver, followed by stomach, spleen, lung, bone, soft tissue, and skin. Case Presentation: In this paper, a patient with multiple mass lesions in the liver with a diagnosis of EHE who underwent liver transplantation is presented. Conclusion: It has an intermediate degree of malignancy between benign hemangioma, and malignant hemangiosarcoma. It can manifest with nonspecific symptoms or hepatic failure. Generally it is seen as a diffuse hepatic disease. The most optimal treatment alternatives are liver resection, and transplantation.

Anahtar Kelimeler

Hemangioendothelioma, liver transplantation, liver tumor

Kaynakça

• Dong K, Wnag X, Feng JL et al. Pathological characteristics of liver biopsies in eight patients with hepatic epithelioid hemangio endothelioma. Int J Clin Exp Pathol 2015;8(9): 11015-23.
• Pregliasco AG, Wendum D, Goumard C et al. Hepatic epithelioid hemangioendothelioma. Clin Res Hepatol Gastroenterol 2015 Nov pii: S2210-7401(15)00254-5.
• Mehrabi A, Kashfi A, Fonouni H et al. Primary malignant hepatic epithelioid hemangioendothelioma: A comprehensive rewiew of the literature with emphasis on the surgical therapy. Cancer ;107:2108-21.
• Weiss SW, Enzinger FM. Epithelioid hemangioendothelioma: A vascular tumor often mistaken for a carcinoma. Cancer ;50:970-81 . Sangro B, Inaarrairaegui M, Fernandez-Ros N. Malignant epitheloid hemangioendothelioma of the liver successfully treated with sorafenib. Rare Tumors 2012;4:e34 .
• Caruso S, Miraglia R, Maruzelli L et al. An unusual presentation of malignant hepatic epithelioid hemangioendothelioma with left pleural and pulmonary localization.Pediatr Radiol 2008;38:1027-30
• Ji ZF, Shen XZ, Zhang DY et al. Hepatic epithelioid hemangio endothelioma: a report of six patients. J Dig Dis 2010;11:254-8.
• Tsuneyoshi M, Dorfman HD, Bauer TW. Epithelioid hemangio endothelioms of bone: a clinicopathologic, ultrastructural, and immunohistochemical study. Am J Surg Pathol 1986;10:754-64.
• Langrehr JM, Petersen I, Pfitzmann R, Lopez-Hanninen E. Malignant epithelioid hemangioendothelioma of the liver. Result of surgical treatment strategies. Chirurg 2005;76:1161-7.
• Lerut JP, Orlando G, Sempoux C et al. Hepatic hemangio endothelioma in adults: Excellent outcome following liver transplantation. Transpl Int 2004;17:202-07.
• Ben-Haim M, Roayaise S, Ye MQ et al. Hepatic epithelioid hemangioendothelioma: Resection or transplantation, which and when? Liver Transpl Surg 1999;5:526-31.
• Lerut JP, Orlando G, Adam R. The place of liver transplantation in the treatment of hepatic epitheloid hemangioendothelioma: report of the European liver transplant registry. Ann Surg. 2007 Dec;246(6):949-57.