Prolotherapy: Practices, Experiences and Observations Concerning Adverse Effects of Physician in Turkey

Yıl 2019, Cilt: 5 Sayı: 1, 54 - 59, 01.01.2019

Hakan Yaman İsmet Akcay Sedat Yildiz

https://doi.org/10.5455/umj.20190605072500

Öz

Background: Prolotherapy is a newly emerging field in Turkey and the aim of this study was survey physicians involved in prolotherapy concerning their practices, experiences and observations concerning adverse effects during prolotherapy administration in Turkey. Material Methods: The study was cross-sectional and observational in nature. A purposeful sample of physicians n=14 , who practiced prolotherapy wer invited to participate in this study. A questionnaire consisting of items on socio-demographics, training, and practice of prolotherapy was applied to these volunteering practitioners, who gave verbal consent before participating. Data of this study has been analyzed with descriptive analysis. Results: The participants mainly men 85.7% . Their age were 38.8 and were trained in the Turkish Prolotherapy Clinic, Istanbul 50.0% . All participants 100% mentioned, that prolotherapy is safe They were practicing prolotherapy since 3.6 years. Most participants n=13; 92.9% stated that they felt, that prolotherapy was safe for their patients. Problems like pain 100% , ecchymosis 64.3% , numbness 28.6% , and edema 14.3% were the most common observed problems at the site of injection. Four 28.6% participants observed at least one adverse incident after prolotheraphy injection. Two 14.3% stated, that their patient was hospitalized due to this incident. Their reasons for hospitalistion was pneumothorax and anaphylactic shock n=1; 7.1% . None 100% were sued for malpractice due to this adverse effects. Conclusion: The procedure-related risks should not be underestimated. Prolotherapy seems to be safe medical procedure in the extremities. Special caution should be given to areas like the thorax and spine. Prolotherapy performing physicians and practices should be prepared for anaphylaxia- or bleeding-related medical adverse conditions

Anahtar Kelimeler

Integrative medicine, complementary medicine, prolotherapy, injections, pain, Turkey

Kaynakça

• 1. Hauser RA, Lackner JB, Steilen-Matias D, Harris DK. A Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain. Clin Med Insights Arthritis Musculo skelet Disord. 2016 Jul 7;9:139-59
• 2. Hung CY, Hsiao MY, Chang KV, Han DS, Wang TG. Comparative effectiveness of dextrose prolotherapy versus control injections and exercise in the management of osteoarthritis pain: a systematic review and metaanalysis. J Pain Res. 2016 Oct 18;9:847-857
• 3. Yaman Hakan, Vural R. Prolotherapy: A New Method for Chronic Pain Management in Family Medicine. Ankara Med J, 2016;16(2):220-4
• 4. Sit RW, Chung VCh, Reeves KD, Rabago D, Chan KK, Chan DC, Wu X, Ho RS, WongSY. Hypertonic dextrose injections (prolotherapy) in the treatment of symptomaticknee osteoarthritis: A systematic review and meta-analysis. Sci Rep. 2016 May5;6:25247
• 5. Goswami A. Prolotherapy. J Pain Palliat Care Pharmac other. 2012;26:376–8
• 6. Dagenais S, Ogunseitan O, Haldeman S, Wooley JR, Newcomb RL. Side effects and adverse events related to intraligamentous injection of sclerosing solutions (prolo therapy) for back and neck pain: A survey of practitioners. Arch Phys MedRehabil. 2006 Jul;87(7):909-13
• 7. Dorman TA. Prolotherapy: a survey. J Orthop Med 1993;15:49-50
• 8. Rabago D, Slattengren A, Zgierska A. Prolotherapy in primary care practice.Prim Care. 2010 Mar;37(1):65-80
• 9. Rabago D, Zgierska A, Fortney L, Kijowski R, Mundt M, Ryan M, Grettie J, Patterson JJ. Hypertonic dextrose injections (prolotherapy) for knee osteoarthritis: results of a single-arm uncontrolled study with 1-year follow-up. J Altern Complement Med. 2012 Apr;18(4):408-14
• 10. DeChellis DM, Cortazzo MH. Regenerative medicine in the field of pain medicine: prolotherapy, platelet-rich plasma therapy, and stem cell therapy-theory and evidence. Tech Reg Anesth Pain Manag. 2011;15(2):74–80
• 11. Slattengren AH, Christensen T, Prasad S, Jones K. PURLs: Prolotherapy: a nontraditional approach to knee osteo arthritis. J Fam Pract. 2014 Apr;63(4):206-8
• 12. Hassan F, Trebinjac S, Murrell WD, Maffulli N. The effectiveness of prolotherapy in treating knee osteo arthritis in adults: a systematic review. Br Med Bull. 2017 Jun 1;122(1):91-108
• 13. Sanderson LM, Bryant A. Effectiveness and safety of prolotherapy injections for management of lower limb tendinopathy and fasciopathy: a systematic review. J Foot Ankle Res. 2015 Oct 20;8:57
• 14. Krstičević M, Jerić M, Došenović S, Jeličić Kadić A, Puljak L. Proliferative injection therapy for osteoarthritis: a systematic review. Int Orthop. 2017 Apr;41(4):671-679
• 15. Rabago D, Patterson JJ, Mundt M, Kijowski R, Grettie J, Segal NA, Zgierska A. Dextrose prolotherapy for knee osteoarthritis: a randomized controlled trial. Ann Fam Med. 2013 May-Jun;11(3):229-37.