Bir Köpekte Malignant Perikardiyal Mezotelyoma ve Perikardiyal Efüzyon

Yıl 2009, Cilt: 28 Sayı: 2, 73 - 82, 01.06.2009

Meriç Kocaturk Hakan Salcı Aylin Alasonyalılar - Demirer Nureddin Çelimli

Öz

Anahtar Kelimeler

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Bir Köpekte Malignant Perikardiyal Mezotelyoma ve Perikardiyal Efüzyon

Öz

Kliniğimize kilo kaybı, abdominal dilatasyon, kollaps ve egzersiz intoleransı şikâyetiyle getirilen 15 yaşlı, erkek, Terrier ırkı bir köpeğe malignant perikardiyal mezotelyomaya bağlı perikardiyal efüzyon (PE) tanısı konuldu. Klinik muayenesinde aritmi, zayıf femoral nabız, kardiyak seslerde boğukluk ve juguler dolgunluk belirlendi. EKG’de QRS ile ilgili küçük kompleks oluşumu ve elektrik alternans, toraks radyografisinde; kalbin siluetinde opasite artışı ve pulmoner ödem, ekokardiyografide; PE ve kardiyak tamponat, abdominal ultrasonografide de asites saptandı. Hematolojik ve serum biyokimyasal bulgular ile perikardiyosentez sıvısının sitolojik muayenesi nonspesifikti. İdiopatik PE tedavisine (ampisilin + prednizolon) yanıt alınamayan hastaya bir ay sonra parsiyel perikardiyektomi yapılmasına karar verildi. Postoperatif kardiyopulmoner arrest nedeni ile hastada eksitus letalis şekillendi. Nekropsi muayenesi sonrası doku örnekleri alındı. Perikardiyumdaki neoplastik kitle, makroskobik, mikroskobik ve immunohistokimyasal özellikleri ile perikardiyal epitelyal mezotelyoma olarak tanımlandı. Sonuç olarak EKG ve ekokardiyografinin PE tanımlamasında yüksek doğruluk derecesinde kullanılabilecekleri, mezotelyoma gibi perikardiyal kitlelerin tanısında yetersiz kalınılabileceği gözlendi. İleri yaşlı PE’li köpeklerin tanısal sürecinde mezotelyomanın da düşünülmesi gerektiği kanısına varıldı

Anahtar Kelimeler

Perikardiyal efüzyon, mezotelyoma, köpek

Kaynakça

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