Öz
Yerli ırk, 16 yaşlı bir kısrak, genital
bölgede sebebi bilinmeyen ve iyileşmeyen yara şikayeti ile kliniğimize
getirildi. Kısrağın genel durumu iyiydi ancak genital bölgenin muayenesinde
vulvada anüsün alt yarımını kapsayan, fibrotik üremeyle karakterize, yaygın
açık bir yara belirlendi. Biyopsi alınarak numuneler patoloji laboratuarına
gönderildi. Histopatolojik inceleme sonucu alınan numunelerden yassı hücreli karsinom
tanısı konuldu. Tedavi için önerilen kemoterapi seçenekleri, kısrağın yaşı ve
sağaltımın maliyeti dolayısıyla hasta sahibi tarafından kabul edilmedi. Sunulan
bu olgu ile bir kısrakta vulvar yassı hücreli karsinomun klinik ve
histopatolojik bulgularının rapor edilmesi ve kliniğimizde çok sık
karşılaşılmayan bu neoplazi için olası sağaltım seçeneklerinin tartışılması
amaçlanmıştır.
Anahtar Kelimeler
Kaynakça
- Brewer, C.A., Blessing, J.A., Nagourney, R.A., McMeekin, D.S., Lele, S., Zweizig, S.L. 2006. Cisplatin plus gemcitabine in previously treated squamous cell carcinoma of the cervix: A phase II study of the Gynecologic Oncology Group. Gynecol. Oncol., 100, 385-388.
- Cunningham, M.J., Goyer, R.P., Gibbons, S.K., Kredentser, D.C., Malfetano, J.H., Keys, H. 1997. Primary radiation, cisplatin, and 5-fluorouracil for advanced squamous carcinoma of the vulva. Gynecol. Oncol., 66, 258-261.
- Eifel, P.J., Morris, M., Burke, T.W., Levenback, C., Gershenson, D.M. 1995. Prolonged continuous infusion cisplatin and 5-fluorouracil with radiation for locally advanced carcinoma of the vulva. Gynecol. Oncol., 59, 51-56.
- Fortier, L.A., Mac Harg, M.A. 1994. Topical use of 5-fluorouracil for treatment of squamous cell carcinoma of the external genitalia of horses: 11 cases. J. Am. Vet. Med. Assoc, 205 (8), 1183-5
- Joyce, J.B. 2013. Treatment of a large vulvar squamous cell carcinoma by radical excision and injectable cisplation. Erişim:http://www.itarget.com.br/newclients/abraveq2012/down/2012/weva/124.pdf
- Perrier, M., Schwarz, T., Gonzalez, O., Brounts, S. 2010. Squamous cell carcinoma invading the right temporomandibular joint in a Belgian mare. Can. Vet. J., 51, 885-887.
- Scheck, J.L. 2005. Treatment of an ocular squamous cell carcinoma in a stallion with atrial fibrillation. Can. Vet. J., 46, 922-924.
- Smith, M.A., Levine, D.G., Getman, L.M., Parente, E.J., Engiles, J.B. 2009. Vulvar squamous cell carcinoma in situ within viral papillomas in an aged Quarter Horse mare. Equine Vet. Educ., 21(1), 11-16.
- Taylor, S., Haldorson, G. 2013. A review of equine mucocutaneous squamous cell carcinoma. Equine Vet. Educ., 25 (7), 374-378.
- Theon, A.P., Pascae, J.R., Carlson, G.P., Krag, D.N. 1993. Intratumoral chemotherapy with cisplatin in oily emulsion in horses. J. Am. Vet. Med. Assoc., 202(2), 261-7.
- Wilson, D.A. 1994. Management of perianal squamous cell carcinoma with permanent colostomy in a mare. J. Am. Vet Med. Assoc., 205(10), 1430-1.
Öz
A native
breed, 16 years old mare was presented to our clinics with the complaint of an
idiopathic and non-healing wound on the genital region. General condition of
the mare was normal, but an extensive open wound on the vulva, which was
extending to ventral part of the anus, characterized by fibrotic proliferation
was observed in the examination of the genital region. The biopsy was taken and
the samples were sent to pathology laboratory. As a result of histopathological
examination, squamous cell carcinoma was diagnosed. The suggested chemotherapy
options for treatment were refused by the patient owner because of the age of
the horse and the cost of treatment. With this case presentation, reporting of
the clinical and histopathological result of vulvar squamous cell carcinoma and
possible treatment options for this rare case in a mare was aimed.
Kaynakça
- Brewer, C.A., Blessing, J.A., Nagourney, R.A., McMeekin, D.S., Lele, S., Zweizig, S.L. 2006. Cisplatin plus gemcitabine in previously treated squamous cell carcinoma of the cervix: A phase II study of the Gynecologic Oncology Group. Gynecol. Oncol., 100, 385-388.
- Cunningham, M.J., Goyer, R.P., Gibbons, S.K., Kredentser, D.C., Malfetano, J.H., Keys, H. 1997. Primary radiation, cisplatin, and 5-fluorouracil for advanced squamous carcinoma of the vulva. Gynecol. Oncol., 66, 258-261.
- Eifel, P.J., Morris, M., Burke, T.W., Levenback, C., Gershenson, D.M. 1995. Prolonged continuous infusion cisplatin and 5-fluorouracil with radiation for locally advanced carcinoma of the vulva. Gynecol. Oncol., 59, 51-56.
- Fortier, L.A., Mac Harg, M.A. 1994. Topical use of 5-fluorouracil for treatment of squamous cell carcinoma of the external genitalia of horses: 11 cases. J. Am. Vet. Med. Assoc, 205 (8), 1183-5
- Joyce, J.B. 2013. Treatment of a large vulvar squamous cell carcinoma by radical excision and injectable cisplation. Erişim:http://www.itarget.com.br/newclients/abraveq2012/down/2012/weva/124.pdf
- Perrier, M., Schwarz, T., Gonzalez, O., Brounts, S. 2010. Squamous cell carcinoma invading the right temporomandibular joint in a Belgian mare. Can. Vet. J., 51, 885-887.
- Scheck, J.L. 2005. Treatment of an ocular squamous cell carcinoma in a stallion with atrial fibrillation. Can. Vet. J., 46, 922-924.
- Smith, M.A., Levine, D.G., Getman, L.M., Parente, E.J., Engiles, J.B. 2009. Vulvar squamous cell carcinoma in situ within viral papillomas in an aged Quarter Horse mare. Equine Vet. Educ., 21(1), 11-16.
- Taylor, S., Haldorson, G. 2013. A review of equine mucocutaneous squamous cell carcinoma. Equine Vet. Educ., 25 (7), 374-378.
- Theon, A.P., Pascae, J.R., Carlson, G.P., Krag, D.N. 1993. Intratumoral chemotherapy with cisplatin in oily emulsion in horses. J. Am. Vet. Med. Assoc., 202(2), 261-7.
- Wilson, D.A. 1994. Management of perianal squamous cell carcinoma with permanent colostomy in a mare. J. Am. Vet Med. Assoc., 205(10), 1430-1.
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Olgu sunumları |
| Yazarlar | |
| Yayımlanma Tarihi | 25 Aralık 2017 |
| Yayımlandığı Sayı | Yıl 2017 Cilt: 36 Sayı: 1-2 |